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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:53 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 857 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Tobacco Treatment Clear all

Conditions: Smoking
Interventions: Mindfulness, Quit Line; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Nicotine Dependence, Opiate Dependence
Interventions: Intensive, tailored intervention, NJ Quitline Referral; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Smoking
Interventions: Web+Mobile, Web Only; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 1,266 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Tobacco Cessation
Interventions: Tailored behavioral counseling, Tobacco cessation pharmacotherapy; Behavioral · Drug
Lead sponsor: Iowa City Veterans Affairs Medical Center; Federal
Eligibility: 18 Years to 99 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Smoking, Nicotine Dependence
Interventions: Naltrexone, Bupropion; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Tobacco Dependence
Interventions: C-Raven Virtual Tobacco Cessation Counseling, Nicotine Replacement Product, Community Health Worker, Lung Cancer Screening; Behavioral · Drug · Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 50 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Tobacco Use, Tobacco Use Cessation
Interventions: Tobacco counseling resources; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 4,800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Smokeless Tobacco Cessation
Interventions: #EnufSnuff.TXT- First Responder, Enough Snuff Intervention; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Tobacco Use Disorder
Interventions: Internet-delivered continuing professional development, No intervention arm; Behavioral · Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years and older
Enrollment: 190 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Tobacco Use, Smoking, Smoking Cessation
Interventions: Cognitive-Motivational Feedback, Staff Tobacco Quit Line Referral Implementation Support, Consumer Incentives for Immediate Referral to a Tobacco Quit Line; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Smoking, Body Weight
Interventions: Smoking Cessation, Smoking Cessation plus Weight Loss; Behavioral
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years to 35 Years
Enrollment: 330 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Tobacco Use Disorder, Smoking Cessation
Interventions: Web-based curriculum on tobacco dependence treatment, Tobacco Counseling Role Play, Preceptor Training and Teaching Medical Students, Booster Session; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 13
States / cities: Birmingham, Alabama • Stanford, California • Washington D.C., District of Columbia + 10 more

Conditions: Smoking Cessation
Interventions: Non-invasive vagus nerve stimulator plus nicotine replacement patches, nicotine replacement patches; Combination Product · Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Cigarette Smoker, Current Every Day Smoker, Student
Interventions: APPSPIRE, Focus Group, Survey Administration; Behavioral · Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years to 24 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2020
U.S. locations: 2
States / cities: Houston, Texas

Conditions: Cigarette Smoking, Tobacco Smoking, Smoking, Tobacco
Interventions: nicotine patch plus nicotine gum/lozenge, Intensive Alcohol Intervention; Drug · Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 75 Years
Enrollment: 352 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Secondhand Smoke
Interventions: Nicotine polacrilex, Electronic Cigarette, Dissolvable Tobacco Lozenge; Drug
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 65 Years
Enrollment: 89 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Adherence, Tobacco Use Cessation, Alcohol & Drug Use, Nicotine Transdermal System
Interventions: Lifestyle counseling; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 25 Years
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 3
States / cities: Jacksonville, Florida • Rochester, Minnesota

Conditions: Smoking Cessation, Smoking, Nicotine Dependence
Interventions: Varenicline, Nicotine lozenge, Nicotine Patch; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 99 Years
Enrollment: 1,086 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 2
States / cities: Madison, Wisconsin • Milwaukee, Wisconsin

Conditions: Diabetic Foot Ulcer
Interventions: CARE-D-Foot-Nav, Standard of care; Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use
Interventions: Screening; Other
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Smoking, Smoking Cessation
Interventions: Nicotine Patch, Tobacco Quit Line Program; Drug · Behavioral
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years and older
Enrollment: 1,298 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2014
U.S. locations: 2
States / cities: Memphis, Tennessee • Lackland Air Force Base, Texas

Conditions: Smoking Cessation
Interventions: Ganaxolone, Nicotine Patch; Drug
Lead sponsor: Jed E. Rose; Other
Eligibility: 18 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 4
States / cities: Charlotte, North Carolina • Durham, North Carolina • Raleigh, North Carolina + 1 more

Conditions: Smoking, Nicotine Dependence, Mental Disorders
Interventions: Cognitive / Motivational Individual Sessions, Attention Control Individual Sessions, Nicotine Patch, Group Curriculum; Behavioral · Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 99 Years
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Coronary Artery Disease, Smoking Cessation
Interventions: genotype-guided therapy, Nicotine patch, Smoking cessation counseling; Other · Drug · Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: St Louis, Missouri

Search by objective public record fields.

Meriter Mindfulness Training for Smokers Program and Study

Developing a Smoking Cessation Intervention for Methadone Maintained Smokers

Web and Mobile Smoking Cessation

A Stepped Care Approach to Treating Tobacco Use in Rural Veterans

Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain

C-Raven, a Virtual Tobacco Cessation Intervention in the Community

Automating Tobacco Cessation in Primary Care

Smokeless Tobacco Cessation Intervention for Firefighters

Dental Tobacco Control.Net:Improving Practice

Salvation Army Tobacco Quit Line Referral Implementation Trial

Treating Adults at Risk for Weight Gain With Interactive Technology

Tobacco Treatment Medical Education in 10 Medical Schools

A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation

APPSPIRE App in Preventing Students From Smoking

Enhancing Smoking Cessation in the Homeless Population

Preliminary Investigation of Novel Methods to Reduce Children's Secondhand Smoke Exposure

Smoking Cessation for Young Adults Who Binge Drink - 1

A Comparative Effectiveness & Long Term Health Study in Wisconsin Smokers

Comprehensive Assistance and Resources for Effective Diabetic Foot Navigation

TAPS-ESP: Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use Electronic Spanish Platform

Evaluating a Telephone-Based Smoking Cessation Program Among People in the Military (The AFIII Study)

Proof-Of-Concept Investigation With a Neurosteroid Analog (Ganaxolone) as a Smoking Cessation Candidate

Helping Those With Mental Illness Quit Smoking

PRISM-GENOMICS-Smoking Cessation for Patients With Coronary Artery Disease Undergoing Cardiac Catheterization or Having a Heart Attack at Barnes Hospital in St. Louis Mo