- Conditions
- Postsurgical Pain Management
- Interventions
- TLC590, Ropivacaine
- Drug
- Lead sponsor
- TLC Biopharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 2
- States / cities
- Bellaire, Texas • Houston, Texas
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Total Knee Arthroplasty, Opioid Use
- Interventions
- Dronabinol 5mg Cap, Placebo oral tablet
- Drug · Other
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 114 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Total Knee Arthroplasty
- Interventions
- Clinical decision support tool (CDS tool)
- Other
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 40 Years to 90 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 2
- States / cities
- Aurora, Colorado • Pittsburgh, Pennsylvania
- Conditions
- Postoperative Urinary Retention, Total Hip Arthroplasty, Total Knee Arthroplasty
- Interventions
- Indwelling foley catheter, No foley catheter
- Device · Other
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 388 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Infection
- Interventions
- Not listed
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 111 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Anesthesia, Local, Pain, Postoperative
- Interventions
- Short-term ON-Q, Short-term ON-Q, Long-term ON-Q, Long-term ON-Q
- Device · Drug
- Lead sponsor
- AdventHealth
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Orlando, Florida
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- JNJ-70033093 25 mg, JNJ-70033093 50 mg, JNJ-70033093 100 mg, JNJ-70033093 200 mg, Placebo, Enoxaparin 40 mg
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 1,242 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 9
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 6 more
- Conditions
- Anesthesia
- Interventions
- Continuous Adductor Canal Catheter (ACC), Adductor Canal block with sham catheter
- Device
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 94 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Total Knee Arthroplasty, Knee Replacement, Knee Replacement Arthroplasty, Knee Osteoarthritis
- Interventions
- Smart Knee Implant
- Device
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Knee Arthropathy
- Interventions
- Cement, Cementless, Manual Surgery, Robotic Surgery
- Procedure · Other
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Obesity, Knee Osteoarthritis
- Interventions
- InBody Band 2
- Device
- Lead sponsor
- University of Iowa
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Pain
- Interventions
- bupivacaine liposome injectable suspension, Placebo
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 232 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 14
- States / cities
- Mobile, Alabama • Englewood, Colorado • Miami, Florida + 9 more
- Conditions
- Osteoarthritis of Knee, Edema, Wounds and Injuries
- Interventions
- ODIN1, Standard Care, Diagnostic Device Testing
- Device · Other
- Lead sponsor
- Bioelectric Research Corporation
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016
- U.S. locations
- 2
- States / cities
- Las Vegas, Nevada
- Conditions
- Osteoarthritis, Knee
- Interventions
- Verasense
- Device
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 2
- States / cities
- Bronxville, New York • New York, New York
- Conditions
- Osteoarthritis
- Interventions
- Home PT via web-based platform, Home PT via paper manual, outpatient PT
- Other
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2016
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Total Hip Replacement, Total Knee Replacement
- Interventions
- post op communication software
- Device
- Lead sponsor
- Concentra AI, inc
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 652 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 3
- States / cities
- Phoenix, Arizona • Wichita, Kansas • Baltimore, Maryland
- Conditions
- Total Knee Arthroplasty
- Interventions
- Dexamethasone 4mg, Dexamethasone 8 Mg/mL Injectable Suspension, Dexamethasone 16mg
- Drug
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 438 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 10
- States / cities
- Redwood City, California • San Francisco, California • Chicago, Illinois + 5 more
- Conditions
- Pain, Nociceptive Pain
- Interventions
- FDG radiotracer, PET/MRI, PET/CT imaging
- Drug · Device
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 128 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Arthritis, Knee Osteoarthritis, Arthropathy of Knee
- Interventions
- Stated-Preferences Evaluation Instrument
- Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 348 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities, Rheumatoid Arthritis
- Interventions
- PERSONA Total Knee, Vanguard Total Knee, NexGen Total Knee
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 181 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 5
- States / cities
- Vail, Colorado • Westminster, Colorado • Springfield, Illinois + 2 more
- Conditions
- Osteoarthritis, Pain, Postoperative
- Interventions
- Liposomal bupivacaine, Bupivacaine plus dexamethasone
- Drug
- Lead sponsor
- Albany Medical College
- Other
- Eligibility
- 40 Years to 70 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Albany, New York
- Conditions
- Total Knee Replacement
- Interventions
- hand mixed vancomycin, hand mixed tobramycin, pre-mixed tobramycin
- Drug · Device
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Osteoarthritis
- Interventions
- Physical activity feedback with group meetings, Control
- Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 50 Years to 75 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Osteoarthritis
- Interventions
- Tranexamic Acid (TXA), ε-Aminocaproic Acid (EACA)
- Drug
- Lead sponsor
- Miller Orthopedic Specialists
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 194 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Council Bluffs, Iowa