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Showing 1–24 of 129 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Transcutaneous Spinal Cord Stimulation Clear all
Completed Not applicable Interventional

Brain and Nerve Stimulation for Hand Muscles in Spinal Cord Injury and ALS

NCT02469675
View directory record Official record
Conditions
Spinal Cord Injury (SCI), Amyotrophic Lateral Sclerosis (ALS)
Interventions
Transcranial magnetic stimulation, Median nerve stimulation, Cervical transcutaneous stimulation
Device
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
21 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2018 · Synced Sep 2, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury

NCT07210411
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Tests of sympathetic inhibition, Tests of above level sympathetic activation, Testing of below level sympathetic activation, Epidural stimulation, Transcutaneous stimulation
Diagnostic Test · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Stimulation-based Therapy to Improve Balance in DCM

NCT07298460
View directory record Official record
Conditions
Degenerative Cervical Myelopathy
Interventions
Transcutaneous spinal cord stimulation, Balance and Gait Training
Device · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
50 Years to 90 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 2, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Spinal Cord Stimulation for Functional Recovery in Humans With Tetraplegia

NCT05157282
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
TESS, Training, Motor Task, sham-TESS
Device · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Non-Invasive Spinal Cord Stimulation After Injury

NCT03998527
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Transcutaneous Electrical Spinal Cord Stimulation (TcESCS)
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 99 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2029
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Active, not recruiting Not applicable Interventional

AMPLIFY Study: Transcutaneous Spinal Direct Current Stimulation to Enhance Locomotor Rehabilitation After SCI

NCT05700942
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
High Dose Intervention-tsDCS, Low Dose Intervention-tsDCS
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional

Safety of Transcutaneous Electrical Stimulation Potentiating Recovery in Acute Spinal Cord Injury Syndromes

NCT07090473
View directory record Official record
Conditions
Acute Spinal Cord Injury (SCI), Acute Spinal Cord Injury of Traumatic Origin (tSCI)
Interventions
transcutaneous spinal cord stimulation, sham transcutaneous spinal cord stimulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Not yet recruiting Not applicable Interventional

The Effect of Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation on Bone Strength.

NCT07325149
View directory record Official record
Conditions
Secondary Osteoporosis, Sarcopenia
Interventions
Exoskeleton-Assisted Walking (EAW) + active Transcutaneous Spinal Cord Stimulation (tSCS), Exoskeleton-assisted walking (EAW) + sham Transcutaneous Spinal Cord Stimulation (tSCS)
Device
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
21 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2033
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional

Evaluating Safety and Feasibility of Transcutaneous Spinal Cord Stimulation Following Traumatic and Non-Traumatic Spinal Cord Injury: A Pilot Study

NCT06520020
View directory record Official record
Conditions
Spinal Cord Stimulation, Electric Stimulation Therapy, Traumatic Spinal Cord Injury, Cervical Myelopathy
Interventions
Transcutaneous Spinal Cord Stimulation (Tc-SCS)
Device
Lead sponsor
Francis Farhadi
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Transcutaneous Electrical Spinal Cord Stimulation for Lower Limbs

NCT01949285
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Transcutaneous Electrical Spinal Cord Stimulation
Device
Lead sponsor
NeuroEnabling Technologies, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Sep 2, 2026, 5:32 AM EDT
Suspended Not applicable Interventional

Non-Invasive Electrical and Magnetic Neuromodulation in Persons With Chronic Spinal

NCT05994846
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases
Interventions
RISES-T System
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Sep 2, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional

Brain-Controlled Spinal Stimulation Walking Therapy After Incomplete Spinal Cord Injury (SCI)

NCT06406855
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
BCI-TSCS
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Rehab and Mechanical Ventilation

NCT07427121
View directory record Official record
Conditions
Inspiratory Strength Training (IST), Transcutaneous Spinal Stimulation, Sham Spinal Stimulation
Interventions
Spinal cord stimulation, Inspiratory Strength Training, Sham Stimulation
Device · Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
25 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Not yet recruiting Not applicable Interventional

BreEStim in Managing Neuropathic Pain After Spinal Cord Injury (SCI)

NCT07659743
View directory record Official record
Conditions
Pain Management
Interventions
Active BreEStim Treatment, Sham BreEStim Treatment, The TENS Treatment
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
22 Years to 80 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Transcutaneous Tibial Nerve Stimulation for Spinal Cord Injury Neurogenic Bladder

NCT04350359
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Variable-dose TTNS Protocol 5 x week, Fixed-dose TTNS Protocol, Variable-dose TTNS Protocol 2 x week
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional

Safety and Feasibility of Paired Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) With Upper Limb Rehabilitation in Incomplete Spinal Cord Injury

NCT06543277
View directory record Official record
Conditions
Chronic Incomplete Cervical Spinal Cord Injury (SCI)
Interventions
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Sep 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

Transcutaneous Electrical Spinal Stimulation to Restore Upper Extremity Functions in Spinal Cord Injury

NCT03184792
View directory record Official record
Conditions
Spinal Cord Injury Cervical, Upper Extremity Dysfunction
Interventions
Transcutaneous spinal stimulation, Physical therapy
Device · Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

Combining tsDCS and Exoskeleton Gait Training on Spinal Excitability in SCI

NCT02862080
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
cathode tsDCS, Ekso, anode tsDCS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 19, 2021 · Synced Sep 2, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcutaneous Spinal Cord Stimulation for Chronic Low Back Pain

NCT05265000
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
tSpinalStim
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transcutaneous Spinal Cord Neuromodulation to Normalize Autonomic Phenotypes

NCT04858178
View directory record Official record
Conditions
Spinal Cord Injuries, Autonomic Imbalance, Autonomic Dysreflexia, Orthostatic; Hypotension, Neurogenic
Interventions
Tests of sympathetic inhibition, Tests of sympathetic activation, Testing of autonomic dysreflexia, Transcutaneous spinal cord stimulation
Diagnostic Test · Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 30 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Sep 2, 2026, 5:32 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Device for Bladder Control for Men With SCI

NCT07668063
View directory record Official record
Conditions
Neurogenic Bladder
Interventions
Noninvasive electrical stimulation device to improve bladder control
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Male only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Not listed Not applicable Interventional

Non-invasive Spinal Stimulation as an Adjuvant Therapy for Trunk Control After Pediatric SCI

NCT05091463
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Biostim-5/Neostim transcutaneous spinal stimulator
Device
Lead sponsor
University of Louisville
Other
Eligibility
3 Years to 12 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 23, 2024 · Synced Sep 2, 2026, 5:32 AM EDT
Active, not recruiting Not applicable Interventional

Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce Spasticity

NCT05429736
View directory record Official record
Conditions
Incomplete Spinal Cord Injury, Spasticity, Muscle
Interventions
Motor Skill Training (MST), Transcutaneous Spinal Stimulation (TSS)
Behavioral · Device
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Restoring Arm and Hand Function With Non-invasive Spinal Stimulation

NCT01906424
View directory record Official record
Conditions
Paralysis, Spinal Cord Injury
Interventions
Transcutaneous Electrical Spinal Cord Stimulation
Device
Lead sponsor
NeuroEnabling Technologies, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
2
States / cities
Los Angeles, California • San Juan Capistrano, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Sep 2, 2026, 5:32 AM EDT