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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Trauma-focused Cognitive Behavioral Therapy Clear all
Recruiting Not applicable Interventional

Systematic Redesign of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT)

NCT06941428
View directory record Official record
Conditions
Trauma, Psychological, Trauma and Stressor Related Disorders
Interventions
Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), School-Adapted TF-CBT (S-TF)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
7 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Not applicable Interventional

Online Coping Skills Counseling for Problem Gambling and Trauma

NCT03145792
View directory record Official record
Conditions
Gambling Disorder, Trauma, Psychological, Problem Gambling, Posttraumatic Stress Disorder
Interventions
Seeking Safety, CBT for Pathological Gambling
Behavioral
Lead sponsor
University of Windsor
Other
Eligibility
18 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Newton Center, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 29, 2025 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Not applicable Interventional

Study of Interpersonal Therapy and Complicated Grief Treatment in Adults 50 Years and Older

NCT01244295
View directory record Official record
Conditions
Complicated Grief
Interventions
Complicated Grief Treatment, Interpersonal Therapy
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
50 Years to 95 Years
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 15, 2014 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Not applicable Interventional

Evaluation of the Veterans' In-home Program

NCT01831830
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
The Veterans' In-home Program
Behavioral
Lead sponsor
Corporal Michael J. Crescenz VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 23, 2015 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Hybrid Type 2 Trial of Trauma-Focused Cognitive Behavioral Therapy and a Pragmatic Individual-Level Implementation Strategy

NCT04451161
View directory record Official record
Conditions
Evidence-Based Practices, CBT, School Health Services, Trauma, Psychological
Interventions
Beliefs and Attitudes for Successful Implementation in Schools (BASIS), Trauma-Focused Cognitive-Behavioral Therapy, Treatment as Usual, Attention Control
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
7 Years to 85 Years
Enrollment
292 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Phase 2Phase 3 Interventional

RECONsolidation of Traumatic Memories to ResOLve Post Traumatic Stress Disorder (RECONTROLPTSD)

NCT03827057
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Traumatic Brain Injury
Interventions
Reconsolidation of Traumatic Memories (RTM), Prolonged Exposure (PE)
Behavioral
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Sep 28, 2026, 6:04 PM EDT
Active, not recruiting Not applicable Interventional

Re-entry Continuum for Brain Injury

NCT04386681
View directory record Official record
Conditions
Traumatic Brain Injury, Recidivism
Interventions
Reentry Continuum for Brain Injury (RCBI)
Behavioral
Lead sponsor
Rehabilitation Hospital of Indiana
Other
Eligibility
18 Years and older · Male only
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Greencastle, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Not applicable Interventional Results available

Brief Restructuring Intervention Following Trauma Exposure

NCT02808468
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Alcohol Use Disorders
Interventions
Brief Cognitive Therapy
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Sep 28, 2026, 6:04 PM EDT
Recruiting Not applicable Interventional

Examining the Efficacy of Short-Term Intensive PTSD Treatment on Psychological and Cognitive Impairment Symptoms

NCT07680517
View directory record Official record
Conditions
PTSD, Cognitive Performance
Interventions
Cognitive Processing Therapy, Eye-Movement Desensitization and Reprocessing
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Fayetteville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Phase 1Phase 2 Interventional

Colorado Women's TC Project

NCT00249561
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Recovery by Choice, The Intensive Outpatient Program (IOP)
Behavioral
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 19, 2011 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Not applicable Interventional

Treating Insomnia & Nightmares After Trauma: Impact on Symptoms & Quality of Life

NCT01009112
View directory record Official record
Conditions
Nightmares, Insomnia, Posttraumatic Stress Disorder
Interventions
PTSD + IRT/CBT-I, PTSD + Supportive Care Therapy
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Phase 2 Interventional Results available

Effect of D-cycloserine on Treatment of Posttraumatic Stress Disorder (PTSD) in Youth

NCT01157416
View directory record Official record
Conditions
Posttraumatic Stress Disorders, PTSD
Interventions
D-cycloserine, Placebo pill, CBT
Drug · Behavioral
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
7 Years to 12 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Not applicable Interventional

Cognitive Processing Intervention for Trauma, HIV/STI Risks, and Substance Use Among Native Women

NCT01849029
View directory record Official record
Conditions
Post Traumatic Stress Disorders, Unsafe Sex, Substance Use Disorders
Interventions
Cognitive Processing Therapy-Cognitive
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Toppenish, Washington
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Not applicable Interventional

Implementation of an Evidence Based Post-Traumatic Stress Disorder (PTSD) Treatment in Public Sector Settings

NCT01488539
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
STAIR/NT treatment, Treatment as Usual (TAU)
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
5
States / cities
Farmington, Connecticut • Washington D.C., District of Columbia • Atlanta, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2023 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Not applicable Interventional

Adapting Alcohol Behavioral Couple Therapy for Service Members in Post-Deployment

NCT03589521
View directory record Official record
Conditions
Alcohol Abuse
Interventions
ABCT_Military
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Phase 3 Interventional

Individual PE vs Couples' CBT for Combat-Related Posttraumatic Stress Disorder

NCT02336971
View directory record Official record
Conditions
PTSD, Marital Relationship
Interventions
CBCT for PTSD, Prolonged Exposure
Behavioral
Lead sponsor
Toronto Metropolitan University
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
3
States / cities
Fort Hood, Texas • Fort Sam Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Sep 28, 2026, 6:04 PM EDT
Not yet recruiting Not applicable Interventional

Mindfulness Therapy for Chronic Pain After Intimate Partner Violence

NCT07700355
View directory record Official record
Conditions
Chronic Pain
Interventions
Mindfulness-Based Cognitive Therapy for Trauma-Informed Pain (MBCT-TIP), Health Enhancement Program (HEP)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Not applicable Interventional

Connecticut Child STEPs

NCT03153904
View directory record Official record
Conditions
Anxiety, Depression, Trauma, Behavior Problems
Interventions
Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, and Conduct Problems, Monitoring and Feedback System
Behavioral · Other
Lead sponsor
Harvard University
Other
Eligibility
7 Years to 15 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Sep 28, 2026, 6:04 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD

NCT04961190
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Prolonged Exposure Therapy, Pharmacotherapy with paroxetine or venlafaxine XR
Behavioral · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
304 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
7
States / cities
Birmingham, Alabama • Menlo Park, California • San Diego, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 28, 2026, 6:04 PM EDT
Active, not recruiting Not applicable Interventional

Evaluation of RRFT for Co-occurring SUD and PTSD Among Teens

NCT05384223
View directory record Official record
Conditions
Substance Use Disorders, PTSD
Interventions
RRFT (Risk Reduction through Family Therapy), ENCOMPASS (Integrated Treatment for Adolescents and Young Adults)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
13 Years to 75 Years
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Phase 2 Interventional

Stellate Ganglion Block to Augment Trauma-focused Therapy Among Veterans With PTSD

NCT05107752
View directory record Official record
Conditions
PTSD, Trauma and Stressor Related Disorders, Trauma, Psychological, Post Traumatic Stress Disorder
Interventions
Cognitive Processing Therapy (CPT), Stellate Ganglion Block
Behavioral · Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Not applicable Interventional

Substance Abuse and Trauma in Incarcerated Women

NCT01413984
View directory record Official record
Conditions
Substance Abuse, Trauma, Post Traumatic Stress Disorder, Integrated Treatment, Incarcerated Women
Interventions
Helping Women Recover/Beyond Trauma
Behavioral
Lead sponsor
University of Tulsa
Other
Eligibility
18 Years and older · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Taft, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 17, 2014 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Phase 2 Interventional Results available

Treatment of Smoking Among Individuals With PTSD

NCT00937235
View directory record Official record
Conditions
Cigarette Smoking, Nicotine Dependence, Post-traumatic Stress Disorder, Tobacco Use Disorder
Interventions
Varenicline, Medication Management Counseling, Prolonged Exposure
Drug · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 13, 2017 · Synced Sep 28, 2026, 6:04 PM EDT
Completed Phase 4 Interventional Results available

CPT-SMART for Treatment of PTSD and Cigarette Smoking

NCT03978442
View directory record Official record
Conditions
Smoking, Stress Disorders, Post-Traumatic
Interventions
Smoking Cessation Cognitive Behavioral Therapy (CBT), Bupropion, Cognitive Processing Therapy, Smoking Abstinence Reinforcement Therapy, Yoked Contingency Management
Behavioral · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 28, 2026, 6:04 PM EDT