- Conditions
- Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms, Opioid Use Disorder (OUD), Stimulant Use Disorder, Stimulant Use & Co-occuring Opioid Use Disorders, Co-occurring Mental and Substance Use Disorders, Medications for Opioid Use Disorder
- Interventions
- Cognitive Processing Therapy (CPT), Written Exposure Therapy (WET)
- Other
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 338 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 2
- States / cities
- Little Rock, Arkansas
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Showing 25–48
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- Conditions
- Post Traumatic Stress Disorder
- Interventions
- Prolonged Exposure
- Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Nightmares, Insomnia, Posttraumatic Stress Disorder
- Interventions
- PTSD + IRT/CBT-I, PTSD + Supportive Care Therapy
- Behavioral
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Grief, Depressive Symptoms, Trauma, Psychological
- Interventions
- Accelerated Resolution Therapy
- Behavioral
- Lead sponsor
- University of South Florida
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 54 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Tampa, Florida
- Conditions
- Post Traumatic Stress Disorders, Unsafe Sex, Substance Use Disorders
- Interventions
- Cognitive Processing Therapy-Cognitive
- Behavioral
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Toppenish, Washington
- Conditions
- TBI
- Interventions
- Sildenafil citrate, Functional Near Infared Spectroscopy, Hypercapnia Challenge
- Drug · Device · Other
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 26 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Post Traumatic Stress Disorder
- Interventions
- Partnered Prolonged Exposure (PPE), Prolonged Exposure (PE)
- Behavioral
- Lead sponsor
- United States Department of Defense
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 420 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 4
- States / cities
- Phoenix, Arizona • San Diego, California • Minneapolis, Minnesota + 1 more
- Conditions
- PTSD, Marital Relationship
- Interventions
- CBCT for PTSD, Prolonged Exposure
- Behavioral
- Lead sponsor
- Toronto Metropolitan University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 3
- States / cities
- Fort Hood, Texas • Fort Sam Houston, Texas • San Antonio, Texas
- Conditions
- Posttraumatic Stress Disorder
- Interventions
- Prolonged Exposure Therapy, Pharmacotherapy with paroxetine or venlafaxine XR
- Behavioral · Drug
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 304 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2026
- U.S. locations
- 7
- States / cities
- Birmingham, Alabama • Menlo Park, California • San Diego, California + 4 more
- Conditions
- Posttraumatic Stress Disorder, Depressive Symptoms, Burn Out, Anxiety, Work Related Stress
- Interventions
- WET
- Behavioral
- Lead sponsor
- University of Texas at Austin
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Cigarette Smoking, Nicotine Dependence, Post-traumatic Stress Disorder, Tobacco Use Disorder
- Interventions
- Varenicline, Medication Management Counseling, Prolonged Exposure
- Drug · Behavioral
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 142 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2015
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Conflict, Interparental, Trauma, Psychological
- Interventions
- intensive trauma-focused therapy
- Behavioral
- Lead sponsor
- Trauma Institute & Child Trauma Institute
- Other
- Eligibility
- 6 Years to 16 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2019
- U.S. locations
- 1
- States / cities
- Northampton, Massachusetts
- Conditions
- Alcohol Use Disorder, Substance Use Disorders
- Interventions
- Indigenous Recovery Planning
- Behavioral
- Lead sponsor
- Montana State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 201 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Poplar, Montana
- Conditions
- Posttraumatic Stress Disorder
- Interventions
- Trauma-Focused Cognitive Behavioral Therapy
- Behavioral
- Lead sponsor
- Delaware Division of Prevention and Behavioral Health Services
- Government
- Eligibility
- 7 Years to 17 Years
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2012
- U.S. locations
- 1
- States / cities
- Wilmington, Delaware
- Conditions
- Post Traumatic Stress Disorder
- Interventions
- Psilocybin, Trauma-focused psychotherapy, Standard psychological support
- Drug · Other
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Post Traumatic Stress Disorder
- Interventions
- Transcranial Direct Current Stimulator, Written Exposure Therapy
- Device · Other
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Substance Use Disorders, Posttraumatic Stress Disorder
- Interventions
- Written Exposure Therapy, Neutral Topic Writing
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- West Haven, Connecticut
- Conditions
- Stress Disorders, Post-Traumatic, Anxiety Disorders, Mental Disorder, Traumatic Disorder
- Interventions
- Prolonged Exposure
- Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 109 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2023
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Posttraumatic Stress Disorder, Spinal Cord Injuries
- Interventions
- Prolonged Exposure Therapy
- Behavioral
- Lead sponsor
- Baylor Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2026
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- PTSD
- Interventions
- Prolonged Exposure Therapy for Posttraumatic Stress Disorder
- Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Posttraumatic Stress Disorder, Substance Use Disorders
- Interventions
- Narrative Exposure Therapy
- Behavioral
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- 16 Years to 25 Years
- Enrollment
- 124 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- PTSD, Opioid-use Disorder, Substance Use Disorders
- Interventions
- Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE)
- Behavioral
- Lead sponsor
- Christal L Badour
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Posttraumatic Stress Disorder (PTSD), Substance Use Disorders (SUD), Comorbidity, Trauma and Stressor Related Disorders
- Interventions
- Massed Prolonged Exposure Therapy (M-PE), Standard outpatient SUD care
- Behavioral
- Lead sponsor
- Rutgers, The State University of New Jersey
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 168 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
- Conditions
- Depressive Symptoms, Emotional Depression, Depression, Parent Child Relationship, Parent-Child Relationship, Parent-Child Relations, Stress Disorder, Post Traumatic, PTSD, Parenting, Child Behavior, Emotional Regulation, Emotion Regulation
- Interventions
- Parenting-STAIR Modular (PSTAIR-M), Treatment as Usual (TAU)
- Behavioral
- Lead sponsor
- New York University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 243 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 4
- States / cities
- Colorado Springs, Colorado • Silver Spring, Maryland • Lawton, Oklahoma + 1 more