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Showing 1–24 of 4,397 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers

A Hybrid Effectiveness-Implementation Trial of Group CBT in Urban Schools

NCT02651402
Conditions
Anxiety Disorders
Interventions
FRIENDS for Life, Adapted FRIENDS, Train-the-Trainer, Train-the-Trainer Plus
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 99 Years
Enrollment
495 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Results available

Scalar Closed Loop Intraoperative Study

NCT03270657
Conditions
Parkinson Disease
Interventions
IPG; RC+S
Device
Lead sponsor
Dennis Turner, M.D.
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Completed No phase listed Observational Results available

Dose Reduction and Discontinuation With Anti-Fibrotic Medications

NCT05779007
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
Pirfenidone, Nintedanib
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
2,778 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Ridgefield, Connecticut
Conditions
Emergency Contraception
Interventions
Etonogestrel implant with Oral Levonorgestrel emergency contraception 1.5mg, Etonogestrel implant with oral placebo
Drug · Device
Lead sponsor
Lori Gawron
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
790 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Enrolling by invitation Phase 4 Interventional

Precision Care for Major Depressive Disorder

NCT06580041
Conditions
Major Depressive Disorder, Depression, Depressive Disorder, Major
Interventions
Pramipexole, Methylphenidate, Phenelzine, Mindfulness-based Stress Sensitivity Therapy (MBSST), Complicated Grief Treatment (CGT), Care as usual (CAU) plan
Drug · Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
San Francisco, California
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Testing Family Firearm Secure Storage Training (FFAST) to Prevent Suicide

NCT07692854
Conditions
Lethal Means Safety, Brief Intervention, Concern Significant Others
Interventions
The Family Firearms Secure storage Training (FFAST) Intervention, Health and Stress Counseling
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Terminated Not applicable Interventional Accepts healthy volunteers Results available

TOGETHER: A Couple's Model to Enhance Relationships and Economic Stability

NCT04227405
Conditions
No Condition
Interventions
Connection to community services through case management, TOGETHER Workshop, Employment Support Services
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years and older
Enrollment
584 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
3
States / cities
College Park, Maryland • Gaithersburg, Maryland • Falls Church, Virginia
Conditions
Premature Birth
Interventions
Interpregnancy Care
Behavioral
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
13 Years to 44 Years · Female only
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
3
States / cities
Jackson, Mississippi
Conditions
Hypertension
Interventions
SERVE OC Intervention, Enhanced Standard Intervention
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
5 Years and older
Enrollment
483 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Irvine, California
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Disrupting SRFOH to Improve Substance Use and Mental Health Outcomes for Parents in Rural Regions

NCT06560866
Conditions
Substance-Related Disorders
Interventions
Just Care for Families
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
Not listed
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Eugene, Oregon
Conditions
Prostate Cancer
Interventions
external beam radiation therapy, brachytherapy, questionnaires
Radiation · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
6
States / cities
Basking Ridge, New Jersey • Commack, New York • Harrison, New York + 3 more
Conditions
Obesity, Overweight, Weight Loss
Interventions
self-monitoring of body weight, self-monitoring of diet, weekly personalized feedback + lessons + action plans
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)

NCT04134767
Conditions
Substance Use, HIV Infections, HCV Infection, Sexually Transmitted Infections (Not HIV or Hepatitis), Overdose, Drug, Opioid Use
Interventions
Health Linkage, Overdose Education
Behavioral
Lead sponsor
April M Young
Other
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Completed Phase 3 Interventional Results available

Homeless Care Management App

NCT03399500
Conditions
Substance Use Disorders, Mental Health Impairment, Health Behavior, Adherence, Patient
Interventions
In-Person Case Management at Homeless Recovery Program, Unlimited Smartphone, Smartphone Based Case Management (SPCM) app
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
403 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Oklahoma City, Oklahoma • Dallas, Texas
Conditions
Adolescent Behavior, Psychosocial Functioning, Coping Behavior, Help-Seeking Behavior, Utilization, Health Care, Depression, Anxiety, Stress Disorders, Post-Traumatic, Emotion Regulation, Child Welfare
Interventions
Stronger Youth Networks and Coping (SYNC)
Behavioral
Lead sponsor
Portland State University
Other
Eligibility
16 Years to 20 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Alcohol Use Disorder, Recovery Outcomes, Digital Health
Interventions
Digital recovery support services
Behavioral
Lead sponsor
Brandeis University
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Alcohol Use Disorder
Interventions
Peer recovery coaching (PRC), Brief Intervention (SBIRT)
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
18 Years to 75 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Greenville, South Carolina • Seneca, South Carolina
Conditions
High-risk Prostate Cancer, Prostate Cancer
Interventions
HSV-Tk, Valacyclovir, Bicalutamide, Leuprolide Acetate, Brachytherapy, External beam radiotherapy, Radical prostatectomy
Drug · Radiation · Procedure
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Houston, Texas
Conditions
Venous Ulcer of Leg
Interventions
IVUS, Continued Compression Therapy/Stockings
Diagnostic Test · Other
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
8
States / cities
Darien, Connecticut • Winter Park, Florida • Chicago, Illinois + 5 more
Not listed Not applicable Interventional Accepts healthy volunteers

GETSmart: Guided Education and Training Via Smart Phones to Promote Resilience

NCT02170194
Conditions
Subthreshold PTSD
Interventions
Resilience Enhancement Training via Smart Phone, Daily Text Messages
Behavioral
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Sarcoma
Interventions
Non-Metastatic and Resectable, Metastatic and Un-resectable, No evidence of disease, under surveillance, ALT or WDLS
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
Charlotte, North Carolina • Winston-Salem, North Carolina
Terminated Phase 2 Interventional Results available

Phase II of Neoadjuvant and Adjuvant Capmatinib in NSCLC

NCT04926831
Conditions
Non-small Cell Lung Cancer
Interventions
capmatinib
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 90 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
6
States / cities
La Jolla, California • Sacramento, California • Fairfax, Virginia
Completed No phase listed Observational Accepts healthy volunteers

Examining Effects of Ocrevus on Cognitive Fatigue Using fMRI

NCT04448977
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
Ocrevus
Drug
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 64 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
West Orange, New Jersey
Conditions
Polycystic Kidney, Autosomal Dominant
Interventions
Tolvaptan
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
11
States / cities
Denver, Colorado • Jacksonville, Florida • Atlanta, Georgia + 8 more