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ClinicalTrials.gov public records Last synced Nov 7, 2026, 10:38 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2545–2568 of 3,107 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Treatment of depression Clear all

Conditions: Mild Cognitive Impairment
Interventions: Not listed
Lead sponsor: Pamlab, Inc.; Industry
Eligibility: 55 Years to 89 Years
Enrollment: 700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Springfield, Massachusetts

Conditions: Cancer, Depression
Interventions: Ketamine, Placebo; Drug · Other
Lead sponsor: Scott A. Irwin, MD, PhD; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Bipolar Disorder
Interventions: Uridine; Drug
Lead sponsor: University of Utah; Other
Eligibility: 13 Years to 18 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Depression
Interventions: Cognitive Therapy, Medications; Behavioral · Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 452 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2014
U.S. locations: 3
States / cities: Chicago, Illinois • Philadelphia, Pennsylvania • Nashville, Tennessee

Conditions: Depression
Interventions: Depression Care Management (DCM), Enhanced Care; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 60 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: White Plains, New York

Conditions: Delirium, Pain, Back, Spinal Fusion, Thoracolumbar Interfascial Plane Block
Interventions: Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Blood Test, 3D CAM Delirium Severity Scoring, Generalized Anxiety Disorder 7-item (GAD-7) scale, Numerical Rating Score (NRS), PROMIS-Pain Interference, Oswestry Disability Index (ODI), Saint Louis University Mental Status Examination (SLUMs), Delirium Rating Scale-Revised-98 (DRS), Telephone Interview for Cognitive Status - Modified (TICS-M), Opioid Equivalents measured by Morphine Milligram Equivalents (MME), Patient Health Questionnaire depression scale (PHQ-8), Pain Catastrophizing, Fear Avoidance Beliefs Questionnaire (FABQ), Opioid Side Effects and Likeability Questionnaire, Daily Pain Trajectory, Tampa Scale of Kinesiophobia, Quality of Recovery 15; Drug · Diagnostic Test · Other
Lead sponsor: University of Iowa; Other
Eligibility: 65 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Bipolar Disorder, Depression
Interventions: Sertraline, Lithium carbonate; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 65 Years
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 3
States / cities: Los Angeles, California • Palo Alto, California • Mason, Ohio

Conditions: Combat Related Symptoms, Irritability, Anger
Interventions: cranial electrotherapy stimulation (CES) with Alpha-Stim, placebo; Procedure
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 2
States / cities: Fort Hood, Texas • Fort Sam Houston, Texas

Conditions: Multiple Sclerosis, Multiple Sclerosis (MS)
Interventions: My MS Toolkit; Device
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Opiate Dependence, Suicidal Ideation, Depression, Opioid Use, Opioid-Related Disorders, Opioid-use Disorder, Major Depressive Disorder
Interventions: Accelerated intermittent theta-burst stimulation (aiTBS); Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Depression, Postpartum
Interventions: Mother-Infant Group Psychotherapy, Interpersonal Psychotherapy; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older · Female only
Enrollment: 147 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2008
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Intervention, Control
Interventions: Dyadic Intervention, Patient Only Intervention; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 21 Years and older
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2026
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Major Depression
Interventions: electroconvulsive therapy, electroconvulsive therapy plus propofol, propofol; Procedure · Drug
Lead sponsor: Loma Linda University; Other
Eligibility: 45 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Multiple Sclerosis, Pilates Exercise, Walking, Balance, Fatigue in Multiple Sclerosis, Pain Management, Quality of Life, Depression, Cognition, Fatigue
Interventions: Pilates; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Cognitive Impairment, no Dementia (CIND)
Interventions: Aerobic Exercise, DASH diet, Health education control; Behavioral · Other
Lead sponsor: Duke University; Other
Eligibility: 55 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Post-Traumatic Stress Disorder
Interventions: Yoga treatment; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 108 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Anxiety Disorders, Depression
Interventions: Unified Protocol for Adolescents (UP-A); Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 12 Years to 18 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Depression
Interventions: Peer-assisted computerized CBT, Enhanced usual care; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 330 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 3
States / cities: Ann Arbor, Michigan • Battle Creek, Michigan • Detroit, Michigan

Conditions: Anxiety, Depression, Stress Disorders, Post Traumatic
Interventions: Collaborative Care for Women Veterans; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older · Female only
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 3
States / cities: San Diego, California • West Los Angeles, California • Portland, Oregon

Conditions: Anxiety Disorders, Depression
Interventions: Coping Cat/CAT Project, Primary and Secondary Coping Enhancement Therapy; Behavioral
Lead sponsor: Rutgers University; Other
Eligibility: 7 Years to 17 Years
Enrollment: 247 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2020
U.S. locations: 1
States / cities: Piscataway, New Jersey

Conditions: Chronic Disease
Interventions: Intervention: Integrative Community Therapy-based Psychodrama, Control: Improvisational Theatre; Behavioral
Lead sponsor: Geisinger Clinic; Other
Eligibility: 5 Years to 19 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Wilkes-Barre, Pennsylvania

Conditions: Anxiety Disorders and Symptoms, Depression
Interventions: Positive Valence System Treatment; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 55 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Brain Injury
Interventions: extubation, continued intubation; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Postpartum Depression
Interventions: Mothers and Babies Virtual Group Intervention; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 16 Years and older · Female only
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Search by objective public record fields.

A Retrospective Analysis of Cerefolin NAC® in Cognitively Impaired Patients

Study of Oral Ketamine Versus Placebo for Treating Depression in Patients Undergoing Treatment for Cancer

Oral Uridine for Treatment of Bipolar Depression in Adolescents

Prevention of Recurrence in Depression With Drugs and CT

Treatment for Depressed Primary Care Patients

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

Bipolar II Depression: Lithium, SSRI, or the Combination

Cranial Electrotherapy Stimulation (CES) for Soldiers With Combat-Related Symptoms

My MS Toolkit: An Internet-Based Depression Self-Management Program for Adults Living With Multiple Sclerosis

Accelerated Intermittent Theta-Burst Stimulation for Opiate Use Disorder

Group Therapy for Postpartum Depression

A Sleep Intervention for Cancer Patients and Their Caregivers

The Effect on Cognition of Terminating ECT Induced Seizures With Propofol

The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis

ENLIGHTEN: Exercise and NutritionaL Interventions for coGnitive and Cardiovascular HealTh ENhancement

Evaluation of a Yoga Intervention for Post-Traumatic Stress Disorder

A Waitlist-Controlled Trial of the Unified Protocol for the Treatment of Emotional Disorders in Adolescents

Veteran Peer-Assisted Computerized Cognitive Behavioral Therapy for Depression

Collaborative Care for Women Veterans

Process and Outcomes in CBT for Anxious and Depressed Youth

Theatre in Adolescents With Chronic Medical Conditions (CMCs)

Positive Valence System Enhancement Treatment for Anxiety and Depression: Clinical Efficacy and Neural Changes

A Prospective Trial of Elective Extubation in Brain Injured Patients.

Preventing Postpartum Depression in Immigrant Latinas