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ClinicalTrials.gov public records Last synced Nov 7, 2026, 12:50 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2617–2640 of 3,107 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Treatment of depression Clear all

Conditions: Oropharyngeal Cancer, Head and Neck Cancer
Interventions: Questionnaire, Depression Intervention; Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 185 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Post Intensive Care Unit Syndrome
Interventions: App Intervention; Behavioral
Lead sponsor: Kent State University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Akron, Ohio

Conditions: Maternal Depression, Child Behavior Problem
Interventions: Attachment and Biobehavioral Catch up, Attachment and Biobehavioral Catch up Plus Depression Treatment; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 2 Years and older · Female only
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Parkinson's Disease
Interventions: Aerobic walking, Usual care with PD specific health education; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 40 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 2
States / cities: Iowa City, Iowa

Conditions: Behavioral Economics, Gifts, Financial, Point
Interventions: Neuroflow app: Mental health and wellbeing resources for adults; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 107 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Major Depression
Interventions: Psilocybin, modafinil, zolpidem, pimavanserin; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2031
U.S. locations: 4
States / cities: San Diego, California • San Francisco, California • Minneapolis, Minnesota + 1 more

Conditions: Major Depressive Disorder
Interventions: Vilazodone; Viibryd, Paroxetine; Paxil; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 60 Years and older
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Major Depressive Disorder
Interventions: Escitalopram; Drug
Lead sponsor: Forest Laboratories; Industry
Eligibility: 7 Years to 11 Years
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 16
States / cities: Dothan, Alabama • San Diego, California • Santa Ana, California + 13 more

Conditions: Major Depressive Disorder
Interventions: SPD489 (Lisdexamfetamine dimesylate) + Antidepressant; Drug
Lead sponsor: Shire; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 1,570 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 140
States / cities: Birmingham, Alabama • Scottsdale, Arizona • Little Rock, Arkansas + 113 more

Conditions: Mood Disorders, Anxiety Disorders
Interventions: Virtual implementation protocol, e-learning toolkit; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Leominster, Massachusetts

Conditions: Chronic Medical Conditions, Depression
Interventions: FACE-PC; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 60 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Major Depressive Disorder, Depression
Interventions: Transcranial Magnetic Stimulation; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Lung Diseases, Medication Compliance
Interventions: Fluticasone propionate 230mcg for 3 Months, Current Treatment or no treatment, Salmeterol 21mcg for 3 Months; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Sleep Problems, Depressive Disorder and Anxiety Disorders
Interventions: Melatonin lotion, Placebo lotion; Other
Lead sponsor: University of Redlands; Other
Eligibility: 18 Years to 21 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Redlands, California

Conditions: Depressive Disorder, Major
Interventions: JNJ-67953964, Placebo; Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 181 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 28
States / cities: Tucson, Arizona • Little Rock, Arkansas • Glendale, California + 23 more

Conditions: Atrial Fibrillation
Interventions: Catheter ablation; Procedure
Lead sponsor: Texas Cardiac Arrhythmia Research Foundation; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 152 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Diabetic Foot Ulcer
Interventions: CARE-D-Foot-Nav, Standard of care; Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Seasonal Affective Disorder (SAD), Winter Depression, Major Depressive Disorder, Recurrent, With Seasonal Pattern
Interventions: Cognitive-Behavioral Therapy (CBT), Light Therapy (LT); Behavioral · Device
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 177 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Bipolar Depression
Interventions: lurasidone + (lithium or divalproex), Placebo + (lithium or divalproex); Drug
Lead sponsor: Sumitomo Pharma America, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 348 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 27
States / cities: Little Rock, Arkansas • Anaheim, California • Chino, California + 21 more

Conditions: Psychotic Depression
Interventions: Aripiprazole; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Bipolar Disorder
Interventions: Simvastatin, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Depressive Disorder, Major
Interventions: Computer-tailored intervention; Behavioral
Lead sponsor: Pro-Change Behavior Systems; Other
Eligibility: 18 Years and older
Enrollment: 902 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 2
States / cities: Chicago, Illinois • Newton, Massachusetts

Conditions: Cystic Fibrosis, Depression, Anxiety
Interventions: Cognitive Behavioral Therapy (CBT); Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 12 Years to 17 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 3
States / cities: Kansas City, Kansas • Boston, Massachusetts • New York, New York

Conditions: Depressive Disorder, Major
Interventions: BI 1569912, Placebo; Drug
Lead sponsor: Boehringer Ingelheim; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 243 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 21
States / cities: Tucson, Arizona • Oceanside, California • Orange, California + 17 more

Search by objective public record fields.

Depression and Adherence in Head and Neck Cancer

Self-care App for Family Members of ICU Patients.

Attachment and Biobehavioral Catch-up and Depression Treatment

Aerobic Exercise in Parkinson's Disease

Investigating How Incentives Impact Engagement With an Online Mental Health Application (Neuroflow)

Psilocybin for Depression in Veterans

Vilazodone for Treatment of Geriatric Depression

Safety Study of Escitalopram in Children 7 to 11 Years of Age With Major Depressive Disorder

SPD489 Adult Major Depressive Disorder (MDD) Open-label Safety and Tolerability Rollover Extension Study

Online Training for Addressing Perinatal Depression

FACE-PC: Family-Centered Care for Older Adults With Depression and Chronic Medical Conditions in Primary Care

Mechanism of Action of Transcranial Magnetic Stimulation

Uncontrolled Lower Respiratory Symptoms in the WTC Survivor Program

The Impact of Melatonin Lotion on Sleep and Mental Health

A Study to Explore the Efficacy of JNJ-67953964 in the Treatment of Depression

Impact of Anxiety on Cardiac Substrate Modification in Women With Atrial Fibrillation Undergoing Catheter Ablation

Comprehensive Assistance and Resources for Effective Diabetic Foot Navigation

Cognitive-behavioral Therapy vs. Light Therapy for Preventing SAD Recurrence

Lurasidone - A 6-week Study of Patients With Bipolar I Depression (Add-on)

The Combination of Aripiprazole and Antidepressants in Psychotic Major Depression

Simvastatin Augmentation of Lithium Treatment in Bipolar Depression

An Expert System to Reduce Depression in Primary Care

Pilot Study of a CF-specific CBT Intervention for Adolescents

A Study to Test Different Doses of BI 1569912 in People With Depression Who Take Anti-depressive Medicine