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ClinicalTrials.gov public records Last synced Oct 3, 2026, 6:19 PM EDT

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Showing 25–40 of 40 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Trier social stress test Clear all
Completed No phase listed Observational Accepts healthy volunteers

Stress and Coping in Caregivers of Younger Patients With Cancer

NCT02725385
View directory record Official record
Conditions
Anxiety, Depression
Interventions
Laboratory Biomarker Analysis, Physiologic Testing, Questionnaire Administration
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Oct 3, 2026, 6:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity

NCT07244809
View directory record Official record
Conditions
Adverse Childhood Experience, Endothelial Function (FMD), Endothelial Injury, Mitochondrial Function, Oxidative Stress, Psychosocial Influence on Cardiovascular Disease
Interventions
Mitoquinone mesylate (MitoQ), Placebo
Dietary Supplement
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 29 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 3, 2026, 6:19 PM EDT
Recruiting Not applicable Interventional

Cognitive Vulnerability to Stress in Individuals at Risk for Alzheimer's Disease

NCT05795634
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer Disease
Interventions
Trier Social Stress Test
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 3, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining Cortisol and Alpha Amylase in a Healthy Sample of Youth and Adults

NCT02490280
View directory record Official record
Conditions
Anxiety
Interventions
Trier Social Stress Test
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
11 Years to 34 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 3, 2015 · Synced Oct 3, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Influence of Melatonin on Cardiovascular and Thermoregulatory Responses to Stress

NCT07138443
View directory record Official record
Conditions
Stress, Mental Stress
Interventions
Melatonin 3 MG Oral Tablet, Placebo Oral Tablet
Dietary Supplement
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 70 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 3, 2026, 6:19 PM EDT
Completed Not applicable Interventional Results available

Stress and Marijuana Cue-elicited Craving and Reactivity

NCT00613405
View directory record Official record
Conditions
Cannabis Use Disorders
Interventions
Stress + cue exposure, No stress + cue exposure
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 30, 2013 · Synced Oct 3, 2026, 6:19 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Essential Oil Inhalation and Acute Stress Response in Healthy Adults

NCT07473544
View directory record Official record
Conditions
Psychological Stress
Interventions
Essential Oil Inhalation, Placebo Aroma Stick
Other
Lead sponsor
dōTERRA International
Industry
Eligibility
18 Years to 45 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pleasant Grove, Utah
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 3, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maternal Emotions and Diet in Pregnancy

NCT03278392
View directory record Official record
Conditions
Pregnancy Related, Stress, Psychological, Glucose Intolerance During Pregnancy
Interventions
Trier Social Stress Test, Placebo Non-stress task
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Oct 3, 2026, 6:19 PM EDT
Terminated Not applicable Interventional

Acute Stress Response in Migraine Sufferers

NCT03099070
View directory record Official record
Conditions
Migraine Headache
Interventions
Stress, Fasting
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 23, 2023 · Synced Oct 3, 2026, 6:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Depression, Aging, Stress and Heart Health Study

NCT05570721
View directory record Official record
Conditions
Menopause, Depression, Heart Disease in Women, Stress
Interventions
Trier Social Stress Test
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
44 Years to 55 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 3, 2026, 6:19 PM EDT
Active, not recruiting No phase listed Observational

Targeted Realtime Assessment of Chronic Pain in Youth

NCT06867757
View directory record Official record
Conditions
Chronic Pain, Musculoskeletal Pain
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
14 Years to 24 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 3, 2026, 6:19 PM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers

Internalized Stress in Relation to Alcohol Consumption

NCT06091189
View directory record Official record
Conditions
Stress, Physiological, Ethanol Intoxication, Distress, Emotional
Interventions
Relevant Trier Social Stressor Test (TSST), Ethanol, Placebo Trier Social Stressor Test (TSST), Placebo Beverage, Irrelevant Trier Social Stressor Test (TSST)
Behavioral · Drug
Lead sponsor
Texas Tech University
Other
Eligibility
21 Years to 29 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 3, 2026, 6:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neuroendocrine and Immune Response to Stress in Schizophrenia

NCT01975584
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Trier Social Stress Test
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 64 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 27, 2019 · Synced Oct 3, 2026, 6:19 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

MicroRNA Correlates of Childhood Maltreatment and Suicidality

NCT04923685
View directory record Official record
Conditions
Major Depressive Disorder, Suicidal Ideation
Interventions
Trier Social Stress Test
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 60 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Birmingham, Alabama • Huntsville, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 3, 2026, 6:19 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurophysiology, Estrogen, and Stress Exposure in the Emergence of Depression in Adolescent Girls

NCT03450135
View directory record Official record
Conditions
Adolescent Development, Stress, Emotional Disturbances
Interventions
Trier Social Stress Test, Emotional go/no-go task
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
11 Years to 14 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Oct 3, 2026, 6:19 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Stress-induced Drinking in Emerging Adults: the Role of Trauma History

NCT01363180
View directory record Official record
Conditions
Trauma, Posttraumatic Stress Disorder
Interventions
Trier Social Stress Test (TSST), No stress condition
Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 30 Years
Enrollment
197 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Oct 3, 2026, 6:19 PM EDT