Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 9, 2026, 9:26 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
Conditions
Healthy Volunteers
Interventions
[11C] raclopride, liquid nutritive stimulus, Tasteless Oral Stimulus Solution, Minimally Processed Diet, Ultra Processed Diet, Baseline Diet
Drug · Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 45 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Prostate Cancer Metastatic Disease
Interventions
Hypocaloric anti-inflammatory diet
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Male only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Los Angeles, California
Conditions
Celiac Disease in Children, Nutrition Disorder, Child
Interventions
Gluten-Free Diet Education
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Healthy Diet, Obesity
Interventions
Ultra-processed food, high energy density (UPF HL), Ultra-processed food, both low (UPF LL), Ultra-processed food, both high (UPF HH), Unprocessed food diet (UNF LL)
Other
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 60 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Obesity and Overweight
Interventions
Diet containing 80% ultra processed foods, Diet containing 20% ultra processed foods
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
25 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Withdrawn Not applicable Interventional

HEART Kitchen Pilot

NCT07037121
Conditions
Cardiovascular Diseases, Type 2 Diabetes, Obesity and Obesity-related Medical Conditions
Interventions
Whole Food Plant Based Diet Jumpstart
Behavioral
Lead sponsor
Reya Andrews
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Food Allergy
Interventions
Education and Opportunities on Early Introduction, Clinician Supervised Feeding of Known Allergenic Food
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
4 Months to 11 Months
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Stanford, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

The UnProcessed Pantry Project (UP3)

NCT04241133
Conditions
Diet, Healthy, Diet Habit, Disease, Chronic, Health Behavior, Rural Health
Interventions
The UnProcessed Pantry Project (UP3)
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Bozeman, Montana
Conditions
Depression
Interventions
Low UPF Meals (Study Provided), Low UPF Nutritional Guidance, Low UPF Snacks (Study Provided)
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Ultra Processed Versus Unprocessed Diets on Energy Intake

NCT03407053
Conditions
Healthy Diet
Interventions
Ultra-processed diet, Unprocessed diet
Dietary Supplement
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Analysis of MicroBial Metabolites After Eating Refined Food

NCT04308473
Conditions
Dietary Habits
Interventions
Ultra-processed Food Meal, Whole Food Meal
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Testing Ultra-processed Warning Labels in United States

NCT07533877
Conditions
Diet, Consumer Behavior, Nutrition Labeling
Interventions
Label exposure in mock-up UPF products
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
7,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Metabolomics-Driven Insights Into Ultra-Processed Foods

NCT07717970
Conditions
Diet, Food and Nutrition
Interventions
UPF Test Diet A: Starchy, refined grains, UPF Test Diet B: Meat, fish, and bread products, UPF Diet C: Dairy products, including cheese and cream
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Not yet recruiting No phase listed Observational

Dietary Tracking in Heart Failure

NCT07649148
Conditions
Heart Failure, NYHA Class II Heart Failure, NYHA Class III Heart Failure
Interventions
Limiting Ultraprocessed Food (UPF) in Diet
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2040
U.S. locations
1
States / cities
Cleveland, Ohio
Withdrawn Not applicable Interventional Accepts healthy volunteers

Dietary Guidelines for Americans-Ultra Processed Study

NCT07252037
Conditions
Overweight , Obesity, Class I Obesity
Interventions
Low-processed DGA Diet, Ultra-processed DGA Diet
Other
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Grand Forks, North Dakota
Completed Not applicable Interventional Accepts healthy volunteers

Protein-Distinct Macronutrient-Equivalent Diet 2

NCT05581953
Conditions
Healthy Aging
Interventions
Omnivorous, No meat
Other
Lead sponsor
South Dakota State University
Other
Eligibility
65 Years and older
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Brookings, South Dakota
Conditions
Healthy Diet
Interventions
Traditional Diet, Modern Diet
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
35 Years to 60 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional

Diet and Depression

NCT06252701
Conditions
Depression, Major Depressive Disorder, Weight Gain, Obesity, Metabolic Syndrome
Interventions
Reduction of Ultra-processed foods
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Conditions
Food Addiction
Interventions
Low UP (meals provided), Low UP (self-guided), Active Control
Other
Lead sponsor
University of Michigan
Other
Eligibility
22 Years to 60 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Ultra-processed Food Consumption and Health Pilot Study

NCT07318064
Conditions
Obesity & Overweight
Interventions
Purple Diet, Ultra-processed diet
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 50 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Completed Not applicable Interventional Accepts healthy volunteers

Determinants and Outcomes of High vs. Low Ultra-processed Feeding

NCT06310603
Conditions
Healthy Nutrition
Interventions
Low-Processed Food Diet
Other
Lead sponsor
Oklahoma State University
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Stillwater, Oklahoma
Conditions
Crohn's Disease, Active, Crohn's Disease (CD), Diet Interventions
Interventions
Catered Anti-Inflammatory Diet, Diet Guidance for Usual Diet
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
16 Years to 75 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Miami, Florida
Conditions
Ultra-Processed Food Intake, Obesity & Overweight
Interventions
Introductory Educational Workshop, Standard Dietary Change (ON/OFF), Cognitive Dissonance Strategies (ON/OFF)
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
18 Years to 70 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Springfield, Oregon
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Testing Ultra-processed Warning Labels and Not-Ultra-processed Labels in United States

NCT07863570
Conditions
Ultra-processed Labels
Interventions
NIB: Label exposure in mock-up UPF and Not-UPF products, NIB+UPFWL: Label exposure in mock-up UPF and Not-UPF products, NIB+Not-UPF Black: Label exposure in mock-up UPF and Not-UPF products, NIB+Not-UPF Green: Label exposure in mock-up UPF and Not-UPF products
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
12,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland