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ClinicalTrials.gov public records Last synced Oct 22, 2026, 10:07 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 139 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Upper extremity manipulation Clear all
Active, not recruiting Not applicable Interventional

A Novel Program Using Ride-on Toys to Improve Upper Extremity Function in Children With Hemiplegia

NCT06579027
View directory record Official record
Conditions
Hemiplegia, Cerebral Palsy, Children, Only
Interventions
SPEED Training, CRAFT Training
Device · Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
3 Years to 8 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 22, 2026, 10:07 PM EDT
Completed Early Phase 1 Interventional

Behavioral and Pharmacological Reconsolidation Interference in Misophonia

NCT05928689
View directory record Official record
Conditions
Misophonia
Interventions
Propranolol Hydrochloride tablet, Reminder, Counterconditioning, Placebo
Drug · Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 22, 2026, 10:07 PM EDT
Active, not recruiting Not applicable Interventional

Interventions for English Language Learners At-Risk for ADHD

NCT05918991
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Daily Report Card, Language Intervention
Behavioral · Other
Lead sponsor
Florida International University
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 22, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Evaluation of a Novel Integrative and Intensive Virtual Rehabilitation Program for Service Members Post TBI

NCT02899468
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
BrightBrainer Virtual Reality (BBVR) Rehabilitation System
Device
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 67 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 27, 2018 · Synced Oct 22, 2026, 10:07 PM EDT
Terminated Not applicable Interventional

Ketogenic Diet in Patients With Heart Failure

NCT04235699
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
Nutritional and Dietary Manipulation
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Oct 22, 2026, 10:07 PM EDT
Completed Phase 3 Interventional Results available

Assisted Movement Neuro-rehabilitation: VA Multi-site Clinical Trial

NCT00223808
View directory record Official record
Conditions
Cerebrovascular Disorders, Hemiplegia
Interventions
Robot-Low, Robot-High, Control
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
4
States / cities
Palo Alto, California • West Los Angeles, California • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2014 · Synced Oct 22, 2026, 10:07 PM EDT
Completed Not applicable Interventional

The Effect of Combining Spinal Manipulation and Dry Needling in Individuals With Low Back Pain

NCT05802901
View directory record Official record
Conditions
Non-specific Low Back Pain
Interventions
Spinal manipulation, Dry needling, Spinal manipulation and dry needling
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 22, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Specific and Shared Mechanisms Associated With Treatment for Chronic Neck Pain

NCT05940012
View directory record Official record
Conditions
Chronic Neck Pain
Interventions
Manual Therapy
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Oct 22, 2026, 10:07 PM EDT
Recruiting Not applicable Interventional

Chiropractic Care for Episodic Migraine

NCT06229834
View directory record Official record
Conditions
Episodic Migraine
Interventions
Chiropractic Care, Headache Health Education
Procedure · Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 22, 2026, 10:07 PM EDT
Completed Not applicable Interventional Results available

Comparative Effectiveness of Acute Low Back Pain Management

NCT01726803
View directory record Official record
Conditions
Low Back Pain
Interventions
Early Physical Therapy with Usual Care, Usual Care
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 9, 2018 · Synced Oct 22, 2026, 10:07 PM EDT
Recruiting Not applicable Interventional

Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy

NCT06383091
View directory record Official record
Conditions
Total Thyroidectomy
Interventions
Anterior Neck Manual Therapy, Pain Neuroscience Education, Neck Stretches, Scar massage, Voice Exercises, Placebo Anterior Neck Manual Therapy, Placebo Pain Neuroscience Education, Placebo Neck Stretches
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Baltimore, Maryland • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 22, 2026, 10:07 PM EDT
Not listed Not applicable Interventional

B Vitamin Supplementation to Chiropractic Management of Chronic LBP: Pilot Clinical Trial (VCLBP)

NCT06576739
View directory record Official record
Conditions
Recurrent Low Back Pain
Interventions
Spinal Manipulation
Procedure
Lead sponsor
University of Western States
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Oct 22, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Cervical and Upper Thoracic Mobilization and Manipulation for Mechanical Neck Pain

NCT02036905
View directory record Official record
Conditions
Neck Pain
Interventions
Cervical and thoracic mobilization, cervical and thoracic manipulation
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Solon, Ohio • Havertown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2016 · Synced Oct 22, 2026, 10:07 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Exercise in College Students With ADHD

NCT03666416
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Effects of; Exertion, Working Memory, Change in Sustained Attention
Interventions
Sprint Interval Training
Behavioral
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years to 29 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Oct 22, 2026, 10:07 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cannabis Association With Sleep Study

NCT06982950
View directory record Official record
Conditions
Sleep
Interventions
Manipulation of Sleep Duration
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years to 29 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 22, 2026, 10:07 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Use of Osteopathic Medical Manipulation to Decrease the Incidence and Severity of Post-Operative Sore Throat

NCT03720301
View directory record Official record
Conditions
Pharyngitis, Dysphonia
Interventions
Osteopathic Manipulation Treatment, Sham
Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2018 · Synced Oct 22, 2026, 10:07 PM EDT
Active, not recruiting Not applicable Interventional

rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke

NCT03870672
View directory record Official record
Conditions
Stroke, Hemiplegia, Cerebrovascular Accident (CVA), Hemiparesis
Interventions
Contralaterally Controlled Functional Electrical Stimulation, New rTMS approach, Conventional rTMS approach, Sham rTMS approach
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 22, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Changes in Quadriceps Function Following Local or Distant Interventions in Individuals With Patellofemoral Pain

NCT01434966
View directory record Official record
Conditions
Patellofemoral Pain Syndrome, Chondromalacia Patellae, Anterior Knee Pain Syndrome
Interventions
Lumbopelvic Manipulation, TENS- Spine, TENS- Knee
Other
Lead sponsor
Creighton University
Other
Eligibility
15 Years to 50 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 14, 2015 · Synced Oct 22, 2026, 10:07 PM EDT
Completed Not applicable Interventional Results available

Utilizing Gaming Mechanics to Optimize Telerehabilitation Adherence in Persons With Stroke

NCT03985761
View directory record Official record
Conditions
Stroke
Interventions
Home Telerehabilitation using HoVRS
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
40 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 22, 2026, 10:07 PM EDT
Recruiting Not applicable Interventional

Comparing Acupuncture vs. Sham Acupuncture for the Management of Hot Flashes in Prostate Cancer Patients Receiving Hormone Therapy

NCT07594002
View directory record Official record
Conditions
Accupuncture, Prostate Cancer, Hormone Therapy, Hot Flashes
Interventions
Real Acupuncture, Sham Acupuncture
Device
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 22, 2026, 10:07 PM EDT
Not listed Not applicable Interventional

Thrust Manipulation vs. Non-thrust Mobilizations for Mechanical Neck Pain

NCT02619500
View directory record Official record
Conditions
Neck Pain
Interventions
Home Exercise Program, Patient advice, encouragement, and education, Thrust Manipulation, Non-thrust Mobilizations
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 12, 2016 · Synced Oct 22, 2026, 10:07 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Comparative Study: Non-Surgical Spinal Decompression and Spinal Manipulative Therapy- Utilizing a Quantifiable Musculoskeletal Functional Assessment Risk Analysis Tool (MSDR®) in Patients With Chronic Low Back Pain

NCT00732394
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
MSDR
Other
Lead sponsor
MedAppraise, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Clearwater, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2008 · Synced Oct 22, 2026, 10:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Daily Habits & Consumer Preferences Study

NCT05402137
View directory record Official record
Conditions
Obesity
Interventions
Weight stigma intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 22, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Comparing Manipulation, Rehabilitation and Combination of the Two in the Treatment of Knee Osteoarthritis

NCT01188837
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Full Kinetic Chain Manipulative Therapy, Full Kinetic Chain Rehabilitation, Full Kinetic Chain Manipulative Therapy with Rehabilitation
Other
Lead sponsor
Cleveland Chiropractic College
Other
Eligibility
38 Years to 80 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 9, 2012 · Synced Oct 22, 2026, 10:07 PM EDT