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ClinicalTrials.gov public records Last synced Oct 8, 2026, 1:35 AM EDT

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Showing 25–48 of 175 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Usual Care smoking cessation Clear all
Completed Phase 2 Interventional

Reduction of Smoking in Cardiac Disease Patients

NCT00469885
View directory record Official record
Conditions
Cardiovascular Disease, Tobacco Use Disorder
Interventions
Nicotine replacement, Motivational counseling
Drug · Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
2
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of a Couple-Focused mHealth Symptom Self-management Program

NCT03489057
View directory record Official record
Conditions
Prostate Cancer
Interventions
Prostate Cancer Education and Resources for Couples (PERC), usual care plus NCI website
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
40 Years to 75 Years
Enrollment
560 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Creating Smokefree Living Together for Chinese Household Pairs

NCT01592682
View directory record Official record
Conditions
Smoking, Smoke Exposure
Interventions
Smokefree counseling
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Phase 4 Interventional Results available

A Comparative Effectiveness RCT of Optimized Cessation Treatments

NCT02301403
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine patch, in-person counseling and quitline counseling, Preparation Nicotine Mini-Lozenges, Combination NRT (nicotine patch + nicotine mini-lozenges), Intensive In-Person Cessation Counseling, Extended Maintenance Counseling Calls, Automated Adherence Calls
Drug · Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
623 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 13, 2020 · Synced Oct 8, 2026, 1:35 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness of a Multi-Level Smoking Cessation Program for High-Risk Women in Rural Communities

NCT04340531
View directory record Official record
Conditions
Tobacco-Related Carcinoma
Interventions
Best Practice, Survey Administration, Tobacco Cessation Counseling, Training
Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 64 Years
Enrollment
810 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
4
States / cities
Lexington, Kentucky • Columbus, Ohio • Charlottesville, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Capitalizing on a Teachable Moment to Promote Smoking Cessation

NCT02276664
View directory record Official record
Conditions
Smoking Cessation
Interventions
Self-Help (SHI), Usual Care (UC)
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Proactive Outreach for Smokers in VA Mental Health

NCT01737281
View directory record Official record
Conditions
Smoking
Interventions
Proactive outreach, Usual care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
1,938 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
4
States / cities
Tampa, Florida • Minneapolis, Minnesota • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2019 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional Results available

Proactive Tobacco Treatment for Veterans

NCT00608426
View directory record Official record
Conditions
Smoking Cessation, Smoking Tobacco
Interventions
Proactive Outreach with choice of telephone or in-person smoking cessation services
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 80 Years
Enrollment
6,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
5
States / cities
Tampa, Florida • Minneapolis, Minnesota • Jackson, Mississippi + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2015 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional Results available

Comparing Smoking Cessation Interventions Among Underserved Patients Referred for Lung Cancer Screening

NCT04798664
View directory record Official record
Conditions
Smoking Cessation
Interventions
Removal of Financial Barriers, Financial Incentives, Mobile Health Application
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
3,228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
5
States / cities
Oakland, California • Detroit, Michigan • Danville, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Postpartum Return to Smoking

NCT00917943
View directory record Official record
Conditions
Smoking
Interventions
Tailored Counseling Intervention Arm
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
386 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 10, 2013 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional Results available

Financial Incentives for Smoking Cessation Among Mothers

NCT05740098
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Best Practices, Financial Incentives, Nicotine Replacement Therapy
Behavioral · Drug
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older · Female only
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jul 28, 2023 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional

Quit IT: Preliminary Testing of a Web-based, 3D Coping Skills Game to Increase Quitting Self-Efficacy for Maintaining Smoking Abstinence Following Hospitalization

NCT02099097
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
web-based video game (Quit IT), Questionnaires, Salvia sample
Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 30, 2020 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Connect to Quit for Smoking

NCT01299896
View directory record Official record
Conditions
Smoking, Smoking Cessation
Interventions
Coordinated Care, Usual Care
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
633 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 22, 2016 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Phase 4 Interventional

The Long-Term Quitting (Smoking Cessation) Study

NCT02564315
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine Mini-Lozenge for 11 Months, Preparation Phase Behavioral Reduction Counseling, Preparation Phase Recycling Counseling, Preparation Phase Control Treatment, Cessation Phase Supportive Counseling, Cessation Phase Skill Training Counseling, Cessation Phase Brief Information, Cessation Phase Nicotine Patch + Nicotine Mini-Lozenge
Drug · Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
1,154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 17, 2020 · Synced Oct 8, 2026, 1:35 AM EDT
Not listed Not applicable Interventional

Intervening to Promote Tobacco Cessation Following Psychiatric Hospitalization

NCT05672914
View directory record Official record
Conditions
Smoking Cessation
Interventions
Tablet-based sustained care
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Phase 4 Interventional Results available

Smartphone Intervention for Smoking Cessation and Improving Adherence to Treatment Among HIV Patients

NCT03999411
View directory record Official record
Conditions
Smoking, Smoking Cessation, HIV
Interventions
Nicoderm C-Q Transdermal Product, Adherence to Antiretroviral Therapy Counseling, Behavioral Smoking Cessation Counseling, "Crave-to-Quit" app, vDOT "emocha" app
Drug · Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 28, 2024 · Synced Oct 8, 2026, 1:35 AM EDT
Enrolling by invitation Not applicable Interventional

Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation Treatment

NCT05627674
View directory record Official record
Conditions
Smoking, Smoking Cessation, Tobacco Use Cessation
Interventions
Usual Care, RiskProfile-Clin, RiskProfile-Gen
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
915 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional

Integrated Stepped Care for Unhealthy Alcohol Use in HIV

NCT01410123
View directory record Official record
Conditions
Liver Diseases, Alcoholic, Alcoholism, HIV, Hepatitis C
Interventions
Integrated Stepped Care (ISC), Treatment as Usual
Other
Lead sponsor
Yale University
Other
Eligibility
21 Years and older
Enrollment
319 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Oct 8, 2026, 1:35 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Quitxt Mobile Text Messaging Cessation Research Study

NCT05958667
View directory record Official record
Conditions
Smoking Cessation
Interventions
Quitxt text messaging or Chat, Usual care
Behavioral · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 29 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional

Lifestyle Modification Program to Reduce Risk of Coronary Heart Disease in Latina Women With Diabetes

NCT00233259
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Diabetes Mellitus, Type 2
Interventions
Mediterranean Diet, Physical Activity, Stress Management, Social Support, Smoking Cessation, Control group
Behavioral · Other
Lead sponsor
Oregon Research Institute
Other
Eligibility
30 Years to 75 Years · Female only
Enrollment
273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 25, 2011 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional Results available

Nonsmokers Helping Smokers Quit

NCT02010697
View directory record Official record
Conditions
Smoking Cessation
Interventions
Messages targeting nonsmokers, Messages targeting smokers
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
3,125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Phase 3 Interventional Results available

Metabolism Informed Smoking Treatment: The MIST RCT

NCT04590404
View directory record Official record
Conditions
Smoking
Interventions
Post-discharge automated phone calls (IVR) with option to connect with a tobacco coach., Nicotine Replacement Therapy, Varenicline, Metabolism Informed Smoking Treatment (Nicotine metabolite ratio (NMR)-based selection of pharmacotherapy)
Behavioral · Drug · Other
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
18 Years and older
Enrollment
606 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional

Tobacco Treatment Medical Education in 10 Medical Schools

NCT01905618
View directory record Official record
Conditions
Tobacco Use Disorder, Smoking Cessation
Interventions
Web-based curriculum on tobacco dependence treatment, Tobacco Counseling Role Play, Preceptor Training and Teaching Medical Students, Booster Session
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
13
States / cities
Birmingham, Alabama • Stanford, California • Washington D.C., District of Columbia + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Oct 8, 2026, 1:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Technology to Help Low-income and Latino Smokers Quit

NCT02666482
View directory record Official record
Conditions
Smoking Cessation
Interventions
Stop Smoking SF Web App - baseline
Behavioral
Lead sponsor
i4Health
Other
Eligibility
18 Years to 99 Years
Enrollment
1,107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 15, 2018 · Synced Oct 8, 2026, 1:35 AM EDT