Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 21, 2026, 3:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Vaginal Film Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Exploratory Pharmacodynamic Study of Tenofovir-Based Products

NCT02722343
View directory record Official record
Conditions
HIV
Interventions
Tenofovir intravaginal ring, Truvada
Drug
Lead sponsor
CONRAD
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2016 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Multicenter, Open-Label, Non-Comparative Study of the Safety and Contraceptive Efficacy of the Woman's Condom

NCT01223313
View directory record Official record
Conditions
Contraception
Interventions
Woman's Condom
Device
Lead sponsor
Premier Research
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
511 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
10
States / cities
Los Angeles, California • Baltimore, Maryland • New York, New York + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Randomized Cross-Over Study of Self-Insertion of Two Placebo Vaginal Film Formulations

NCT04391036
View directory record Official record
Conditions
Safety, Acceptability
Interventions
High Eudragit® Content Vaginal Film, Low Eudragit® Content Vaginal Film
Device
Lead sponsor
Katherine Bunge
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 21, 2022 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety Study of Monoclonal Antibodies to Reduce the Vaginal Transmission of HSV and HIV

NCT02579083
View directory record Official record
Conditions
HIV, Herpes Simplex Infections
Interventions
MB66, Placebo Film
Drug
Lead sponsor
KBio Inc
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

An Exploratory Study of ZB-06 as a Vaginal Contraceptive Film

NCT04731818
View directory record Official record
Conditions
Contraception
Interventions
ZB-06
Biological
Lead sponsor
KBio Inc
Industry
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Sep 21, 2026, 3:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Acceptability Study of Vaginal Films for HIV Prevention

NCT01231763
View directory record Official record
Conditions
HIV Infections, Anti-Infective Agents
Interventions
No intervention (not applicable)
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 8, 2011 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Safety and Pharmacokinetics of Two Vaginal Film Formulations Containing the Integrase Inhibitor MK-2048

NCT04319718
View directory record Official record
Conditions
Pharmacokinetics, Safety
Interventions
MK-2048 High Eudragit Vaginal Film, MK-2048 Low Eudragit Vaginal Film
Combination Product
Lead sponsor
Hillier, Sharon, PhD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 2, 2023 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Assessing the Safety of Dapivirine Gel and Film Formulations

NCT01548560
View directory record Official record
Conditions
HIV Infections
Interventions
Dapivirine Vaginal Film, Dapivirine Vaginal Gel
Drug
Lead sponsor
International Partnership for Microbicides, Inc.
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 7, 2017 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Phase I Trial to Assess the Safety of Tenofovir Gel and Film Formulations: FAME 04

NCT01989663
View directory record Official record
Conditions
HIV
Interventions
1% vaginally applied tenofovir gel, Tenofovir film- 10mg, Tenofovir Film-40 mg, HEC Placebo Gel, Placebo Vaginal Film
Drug · Other
Lead sponsor
CONRAD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 26, 2016 · Synced Sep 21, 2026, 3:52 AM EDT
Recruiting Not applicable Interventional

Silicone Gel vs. Estrogen Vaginal Cream for the Management of Genitourinary Syndrome of Menopause

NCT05672901
View directory record Official record
Conditions
Genitourinary Syndrome of Menopause
Interventions
StrataMGT, Estrace 0.01% Vaginal Cream
Device · Drug
Lead sponsor
Stratpharma AG
Industry
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Laguna Hills, California • Miami, Florida • Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vaginal Film Administration and Placement Study: FLAG

NCT02908503
View directory record Official record
Conditions
Healthy Women
Interventions
Placebo Film
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 4, 2018 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Development of Adherence Biomarkers for Multiple Microbicide and Multipurpose Prevention Technology (MPT) Dosage Forms

NCT02569697
View directory record Official record
Conditions
HIV
Interventions
HEC Placebo gel, Placebo Intravaginal Ring, Placebo Vaginal Film, Placebo Vaginal Insert
Other
Lead sponsor
CONRAD
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2016 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Comparison of Tenofovir Vaginal Gel and Film Formulations

NCT02280109
View directory record Official record
Conditions
Healthy, HIV
Interventions
Tenofovir Gel, Tenofovir Film
Drug
Lead sponsor
CONRAD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 27, 2016 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Phase 4 Interventional Results available

Effect of Tenofovir on Genital Herpes Simplex Virus (HSV) Shedding

NCT01448616
View directory record Official record
Conditions
Herpes Simplex Type II
Interventions
TDF, Placebo Vaginal Gel, Vaginal TFV Gel, Placebo Tablets
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Sep 21, 2026, 3:52 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Phase 1 Study of Intravaginal KB15A

NCT07222020
View directory record Official record
Conditions
Healthy Subjects
Interventions
KB15A Vaginal Film, Placebo Vaginal Film
Drug
Lead sponsor
ZabBio Inc.
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 21, 2026, 3:52 AM EDT
Active, not recruiting Phase 2 Interventional

REVIVE: Replens Versus Intra-Vaginal Estrogen for the Treatment of Vaginal Dryness on Aromatase Inhibitor Therapy

NCT01984138
View directory record Official record
Conditions
Estrogen Receptor Positive Breast Cancer, Breast Cancer
Interventions
ESTRING, Replens, Vagifem
Drug
Lead sponsor
Polly A. Niravath, MD
Other
Eligibility
18 Years and older · Female only
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Formative Study to Explore the Sensory Perceptions of Vaginal Product Users

NCT01334827
View directory record Official record
Conditions
Microbicide Delivery System Acceptability
Interventions
high volume gel, low volume gel, vaginal film
Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 21, 2026, 3:52 AM EDT
Active, not recruiting Phase 3 Interventional

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

NCT04214067
View directory record Official record
Conditions
Endometrial Endometrioid Adenocarcinoma, Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8, Stage II Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Interventions
Biospecimen Collection, Brachytherapy, Computed Tomography, External Beam Radiation Therapy, Magnetic Resonance Imaging, Pembrolizumab, Quality-of-Life Assessment, Questionnaire Administration, X-Ray Imaging
Procedure · Radiation · Biological + 1 more
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older · Female only
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
275
States / cities
Birmingham, Alabama • Clovis, California • Concord, California + 195 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study of the Safety and Acceptability of a Placebo Vaginal Film: FAME101

NCT03537092
View directory record Official record
Conditions
Safety of Vaginal Film Use
Interventions
Vaginal Film
Device
Lead sponsor
Katherine Bunge
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 12, 2020 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Phase 3 Interventional Results available

The Vaginal Health Trial

NCT02516202
View directory record Official record
Conditions
Atrophy of Vagina, Menopause, Dyspareunia (Female)
Interventions
Vagifem, Replens, Placebo tablet, Placebo gel
Drug · Device · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
45 Years to 70 Years · Female only
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Minneapolis, Minnesota • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Peripheral Neuromodulation on Vaginal Blood Flow - Study 2

NCT06999265
View directory record Official record
Conditions
Female Sexual Dysfunction, Female Sexual Dysfunction Due to Physical Condition
Interventions
Transcutaneous electrical nerve stimulation - Tibial Nerve, Transcutaneous electrical nerve stimulation - Genital Nerve, Neutral and Erotic Film Clip Alternation
Device · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Sep 21, 2026, 3:52 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

MATRIX-002: Trial to Assess Acceptability and Safety of Two Placebo Vaginal Films

NCT06046053
View directory record Official record
Conditions
Safety, Acceptability, Usability
Interventions
Placebo Vaginal Film with Square Corners, Placebo Vaginal Film with Rounded Corners
Drug
Lead sponsor
Rohan, Lisa, PhD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 18, 2024 · Synced Sep 21, 2026, 3:52 AM EDT