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Showing 121–144 of 182 matching trials from the live ClinicalTrials.gov search.
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Nicotine and Pavlovian Bias

NCT06027723
Conditions
Nicotine Vaping, Nicotine Dependence
Interventions
Nicotine, Placebo
Drug · Other
Lead sponsor
University of Southern California
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Recruiting Phase 1 Interventional Accepts healthy volunteers

Effect of Cannabis on E-Cigarette Use Behavior

NCT06609109
Conditions
Cannabis Use, Tobacco Use, Electronic Cigarette Use
Interventions
THC High Dose, THC Low Dose, THC 0mg, E-Cigarette Full Nicotine, E-Cigarette Placebo Nicotine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Vaping Teens, Vaping Behaviors, Vaping Cessation, Tobacco Use Disorder
Interventions
E-cigarette Cessation Manual
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
14 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Miami, Florida
Conditions
E-cigarette Use
Interventions
C-11 labeled nicotine, PET/CT imaging
Drug · Radiation
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Impact of E-cigarette Use on the Body

NCT04972513
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Biospecimen Collection, Nitric Oxide Breath Test, Oscillometry, Spirometry, Survey Administration, Endothelial function
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
15 Years to 25 Years
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
E Cigarette Use
Interventions
adapted vaping cessation intervention
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Diego, California
Completed Not applicable Interventional Accepts healthy volunteers

Trial for Harm Reduction With Incentives & Vaping E-cigarettes

NCT06111053
Conditions
Obesity, Smoking Cessation
Interventions
ENDS, CI, No ENDS, NI
Other
Lead sponsor
Brown University
Other
Eligibility
21 Years to 99 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Withdrawn Not applicable Interventional Accepts healthy volunteers

Peer-to-peer Tobacco and ENDS Prevention

NCT03491865
Conditions
Substance Use
Interventions
REAL media Plus curriculum
Behavioral
Lead sponsor
Real Prevention, LLC
Industry
Eligibility
13 Years to 16 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Clifton, New Jersey
Completed Not applicable Interventional Accepts healthy volunteers Results available

Graphic Messages to Prevent E-Cigarette Use Among Black and Latino Adolescents

NCT04899999
Conditions
Vaping
Interventions
Financial reward graphic message, Health reward graphic message, Self-efficacy graphic message, Social norms graphic message
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
12 Years to 17 Years
Enrollment
362 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Rochester, New York
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Smoking and Vaping in Families

NCT02500238
Conditions
Smoking
Interventions
Saliva sample, Urine Sample, Toe nail clippings, Breath carbon monoxide test
Other
Lead sponsor
University of Florida
Other
Eligibility
6 Years to 17 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Gainesville, Florida • Oklahoma City, Oklahoma
Conditions
Tobacco Dependence Caused by Cigarettes
Interventions
NJOY ACE commercial e-cigarette
Device
Lead sponsor
University of Nevada, Reno
Other
Eligibility
21 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Reno, Nevada
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impact of E-Cigarette Prevention Messages on Adolescents

NCT05985538
Conditions
Vaping Behavior
Interventions
Vaping prevention text messages, Wellness behaviors text messages
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
13 Years to 20 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Perceptions of Vaping Products

NCT06868368
Conditions
Abuse Tobacco, Exposure
Interventions
Biospecimen Collection, Survey Administration, Vaping Topography, Participant's Own Preferred E-cigarette, Nicotine E-cigarette, 6-methyl-nicotine (metatine) e-cigarette
Other · Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 34 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Columbus, Ohio
Recruiting No phase listed Observational Accepts healthy volunteers

Early Detection of Vaping-related Vascular Diseases

NCT05454267
Conditions
Vaping, Blood Vessel Injury
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 40 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Miami, Florida
Conditions
Nicotine Dependence, Nicotine Vaping
Interventions
(S)-Nicotine, (R)- nicotine, Racemic nicotine
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Francisco, California
Completed No phase listed Observational Accepts healthy volunteers Results available

E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease

NCT03863509
Conditions
Tobacco Use, E-Cigarette Use, Cardiovascular Diseases, Pulmonary Disease
Interventions
Cigarettes, E-Cigarettes
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers Results available

Menthol and Mint Experimental Tobacco Marketplace (ETM) Study

NCT04879225
Conditions
Cigarette Smoking, Vaping
Interventions
Tobacco e-liquids, Menthol and Tobacco e-liquids, Mint, Menthol and Tobacco e-liquids, All e-liquid flavors
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Avoidance, Biospecimen Collection, Cigarette Smoking, Eye Movement Measurement, Healthcare Activity, Questionnaire Administration, Refrain from Smoking, Vaping, Standardized E-Cigarette Nicotine Administration
Behavioral · Procedure · Other + 1 more
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 50 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Text Message Quit Vaping Intervention for Adolescents

NCT04919590
Conditions
Vaping, Cessation, Tobacco
Interventions
This is Quitting, Assessment only control, Waitlist control
Behavioral · Other
Lead sponsor
Truth Initiative
Other
Eligibility
13 Years to 17 Years
Enrollment
1,681 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Vaping THC From Electronic Cigarettes

NCT02955329
Conditions
Marijuana Dependence
Interventions
Nicotine, Cannabis, PAX Loose Leaf Vaporizer
Drug · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
San Francisco, California
Conditions
Smoking, Tobacco Use
Interventions
Ventilated cigarettes only, Unventilated cigarettes only, Access to Experimental Marketplace: Ventilated cigarettes + alternative nicotine delivery systems, Access to Experimental Marketplace: Unventilated cigarettes + ANDS
Other
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Minneapolis, Minnesota • Columbus, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Social Media Support Groups for Adolescent Vaping Cessation

NCT07540780
Conditions
Vaping, Vaping Cessation, Nicotine Dependence
Interventions
Social Media Intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Villainous Vape: Advancing Vaping Prevention Among Adolescents Through a Comic Book

NCT07737080
Conditions
Vaping Behaviors
Interventions
Health Impacts of E-cigarettes, Mind Matters: The Body's Response to Nicotine, Tobacco, and Vaping, The Villainous Vape
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
12 Years to 17 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Establishing the Effect of Flavor on the Addictive Potential of Electronic Cigarettes

NCT03905928
Conditions
Tobacco Dependence
Interventions
Nicotine Containing ECIG with tobacco flavor, Nicotine Containing ECIG with Strawberry Vanilla Flavor, Placebo ECIG with Tobacco Flavor, Placebo ECIG with Strawberry Vanilla Flavor
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years to 60 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania