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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Videogame Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Development of a Videogame Prototype Targeting Cigarette and Marijuana Smoking, and Tobacco Product Prevention Among Young Adolescents

NCT03107936
View directory record Official record
Conditions
Smoking
Interventions
smokeSCREEN game
Behavioral
Lead sponsor
Yale University
Other
Eligibility
10 Years to 16 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
4
States / cities
Hamden, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 18, 2018 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional

Clinical Trial of a Serious Game for Individuals With SCI/D

NCT02341950
View directory record Official record
Conditions
Spinal Cord Injury, Spinal Cord Involvement, Spina Bifida, Transverse Myelitis, Polio and Post-polio Syndrome, Syringomyelia, Spinal Stenosis, Spinal Neoplasms, Spinal Cord Diseases
Interventions
SCI Hard
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 29 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 21, 2019 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Digital Intervention to Prevent the Initiation of Opioid Misuse in Adolescents in School-based Health Centers

NCT04941950
View directory record Official record
Conditions
Opioid Misuse
Interventions
PlaySmart, Video Game Control
Behavioral · Other
Lead sponsor
Tyra Boomer
Other
Eligibility
16 Years to 19 Years
Enrollment
533 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
15
States / cities
Bridgeport, Connecticut • Durham, Connecticut • East Hartford, Connecticut + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 25, 2026, 7:45 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Unilateral M1 Anodal tDCS to Enhance Learning in a Gross Movement Videogame Task

NCT07447882
View directory record Official record
Conditions
Motor Activity
Interventions
tDCS
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 45 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Exergaming: A Research Study Testing a Videogame Intervention to Increase Physical Activity for Families

NCT00889122
View directory record Official record
Conditions
Obesity
Interventions
Exergame (DDR)
Behavioral
Lead sponsor
MaineHealth
Other
Eligibility
9 Years to 17 Years
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Scarborough, Maine
Source: ClinicalTrials.gov public record
Updated Aug 3, 2010 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional Results available

Assessing a Novel Virtual Environment That Assists With Activities of Daily Living

NCT05418296
View directory record Official record
Conditions
Dementia, Alzheimer Disease, Neurodegenerative Diseases
Interventions
A novel digital health device
Device
Lead sponsor
mandy
Industry
Eligibility
Up to 110 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Elk Grove, California • Oakland, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 25, 2026, 7:45 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Videogame-based Incentives for Smoking Cessation

NCT01761760
View directory record Official record
Conditions
Smoking Cessation
Interventions
Videogame-based smoking cessation intervention
Behavioral
Lead sponsor
Rowan University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Glassboro, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional Results available

Electroencephalogram (EEG) Study of Inattention Following Treatment With AKL-T01

NCT03844269
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
AKL-T01
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
8 Years to 12 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Rafael, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Sep 25, 2026, 7:45 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

EndeavorOTC® Research Study in College Students

NCT06376032
View directory record Official record
Conditions
Attention, Cognition, University Students
Interventions
EndeavorOTC®
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Cheektowaga, New York • Putney, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Sep 25, 2026, 7:45 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Video Game Play to Alleviate Adolescent Anxiety

NCT05923944
View directory record Official record
Conditions
Anxiety, Anxiety Disorders and Symptoms
Interventions
Eco-Rescue, Bejelewed 3
Behavioral
Lead sponsor
School of Health Sciences Geneva
Other
Eligibility
11 Years to 15 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Interactive Game for HIV Prevention in Early Adolescents

NCT01666496
View directory record Official record
Conditions
HIV, Risk Reduction
Interventions
Experimental Video Game, Off the Shelf Video Game
Behavioral
Lead sponsor
Yale University
Other
Eligibility
11 Years to 14 Years
Enrollment
333 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sensitivity of Project: EVO Monitor Cognitive Measurements to Pharmacological Agents

NCT02822937
View directory record Official record
Conditions
Healthy
Interventions
Methylphenidate, Triazolam, Project: EVO, Placebo
Drug · Other
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
40 Years to 55 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 6, 2016 · Synced Sep 25, 2026, 7:45 PM EDT
Recruiting Phase 2 Interventional

A Digital Intervention for Post-Stroke Depression and Executive Dysfunction

NCT05507138
View directory record Official record
Conditions
Executive Dysfunction, Depression, Stroke
Interventions
AKL-T01, Metacognitive Strategy Training
Device · Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
50 Years to 79 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 25, 2026, 7:45 PM EDT
Active, not recruiting No phase listed Observational

EndeavorOTC™ Prospective Product Registry

NCT06109051
View directory record Official record
Conditions
ADHD
Interventions
EndeavorOTC
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
Not listed
Enrollment
198 participants
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional Results available

Software Treatment for Actively Reducing Severity of ADHD

NCT02674633
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity
Interventions
AKL-T01, AKL-T09
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
8 Years to 12 Years
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
20
States / cities
Dothan, Alabama • Scottsdale, Arizona • Newport Beach, California + 17 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Phase 4 Interventional Results available

PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness

NCT03950427
View directory record Official record
Conditions
Smoking Cessation, Smoking, Tobacco, Mental Illness, Tobacco Use Disorder
Interventions
Videogame-based physical activity, Sedentary videogame, Bupropion, Counseling
Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Phase 1 Interventional

Reducing Aggression in Children and Adolescent on an Inpatient Unit

NCT01377948
View directory record Official record
Conditions
Anger, Aggression
Interventions
ACT with RAGE-Control
Behavioral
Lead sponsor
Gonzalez-Heydrich, Joseph, M.D.
Individual
Eligibility
8 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 11, 2012 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional

Software Treatments for Actively Reducing Severity of Cognitive Deficits in MDD (STARS-MDD)

NCT03310281
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
HOLD: Videogame
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
25 Years to 55 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Garden Grove, California • North Miami, Florida • Charleston, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional

Augmenting Patching Treatment for Amblyopia With Physical Exercise

NCT03822806
View directory record Official record
Conditions
Amblyopia
Interventions
Physical Exercise in addition to Patching
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
5 Years to 16 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility & Characterization of Project: EVO Monitor Cognitive Measurements

NCT02792296
View directory record Official record
Conditions
Healthy
Interventions
Project: EVO Monitor
Other
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
40 Years to 55 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
2
States / cities
Little Rock, Arkansas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 6, 2016 · Synced Sep 25, 2026, 7:45 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Toolkit for Experiential Well-beiNg in Dementia (TEND)

NCT06257563
View directory record Official record
Conditions
Dementia, Alzheimer Disease
Interventions
Isle of TEND Intervention
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Implementation and Dissemination of an Evidence-Based Tobacco Product Use Prevention Videogame Intervention With Adolescents

NCT03815591
View directory record Official record
Conditions
Smoking Cessation, Smoking
Interventions
smokeSCREEN web-based game
Device
Lead sponsor
Yale University
Other
Eligibility
10 Years to 16 Years
Enrollment
560 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Engagement and Aging Mind

NCT05924490
View directory record Official record
Conditions
Age-related Cognitive Decline
Interventions
Real-time strategy-based videogame training, Semantic Knowledge training
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
50 Years and older
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Sep 25, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Formative Research for an HIV Videogame for Young Black Women

NCT02685410
View directory record Official record
Conditions
HIV Prevention, STI Prevention
Interventions
One Night Stan Prototype
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 24 Years · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 12, 2017 · Synced Sep 25, 2026, 7:45 PM EDT