- Conditions
- Chronic Pancreatitis, Chronic Pain
- Interventions
- Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
- Diagnostic Test
- Lead sponsor
- Anna Evans Phillips
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2031
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland • Pittsburgh, Pennsylvania
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Showing 25–48
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- Conditions
- Diabetic Foot Ulcers (DFUs), Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)
- Interventions
- Miro3D Wound Matrix, Standard of Care (SOC)
- Device · Other
- Lead sponsor
- Reprise Biomedical, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 3
- States / cities
- Coconut Creek, Florida • Tamarac, Florida • New York, New York
- Conditions
- Hip Dysplasia, Legg-Calvâe-Perthes Disease, Avascular Necrosis of Hip
- Interventions
- Long-term Follow-up Surveys
- Other
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Cushing's Disease, Cushing Syndrome, Cushing Disease
- Interventions
- Cushing's QoL (Quality of Life Questionnaire), Nottingham Health Profile (NHP), Hospital Anxiety and Depression Scale (HADS), Perceived Stress Scale (PSS), Barratt's Impulsivity Scale (BIS), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), State Food Craving Questionnaire-State (FCQ-S), Trait Food Craving Questionnaire-Trait (FCQ-T), Visual Analogue Scale (VAS), Sensitivity to Reinforcement of Addictive and other Primary Rewards (STRAP-R) food variant
- Other
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Other
- Eligibility
- 14 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2026
- U.S. locations
- 7
- States / cities
- Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
- Conditions
- Pain
- Interventions
- Cryoanalgesia, Standard of Care
- Device · Drug
- Lead sponsor
- AtriCure, Inc.
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 84 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 5
- States / cities
- Los Angeles, California • Ann Arbor, Michigan • Royal Oak, Michigan + 2 more
- Conditions
- Pain, Pregnancy
- Interventions
- painDETECT Questionnaire, Pain Catastrophizing Scale, Pain Intensity Scale, Pain Interference Scale, Pain Behavior Scale, Beck Depression Inventory, Visual Analogue Scale, Patient's Global Impression of Change Scale & Clinical Global Impression-Global Improvement Scale, Transcranial Magnetic Stimulation
- Behavioral · Device
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 18 Years to 45 Years · Female only
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Pain, Anxiety
- Interventions
- Virtual Reality, Standard Procedure Thyroid Biopsy, Standard Procedure PICC Placement
- Device · Procedure
- Lead sponsor
- Temple University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 107 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Normal Physiology, Healthy Volunteers, Pain
- Interventions
- Medoc thermal stimulator, Electric shock stimulator, Cold water bath, Pain assessment performance feedback
- Device · Behavioral
- Lead sponsor
- National Center for Complementary and Integrative Health (NCCIH)
- NIH
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 700 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2027
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Labor Pain
- Interventions
- 50% Nitrous Oxide/50% Oxygen
- Drug
- Lead sponsor
- West Penn Allegheny Health System
- Other
- Eligibility
- 18 Years and older · Female only
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Neuroma Amputation
- Interventions
- Observational
- Other
- Lead sponsor
- Oregon Health and Science University
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Portland, Oregon
- Conditions
- Dry Eye, Neuropathic Pain
- Interventions
- Hyperosmolar Response, Proparacaine Challenge Test, Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) Optional; only for Contact Lens Wearers, Ocular Pain Assessment Survey (OPAS), Visual Analogue Questionnaire
- Other
- Lead sponsor
- Tufts Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 16
- States / cities
- Azusa, California • Pomona, California • San Francisco, California + 10 more
- Conditions
- Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb, Osteoarthritis Shoulder, Pain, Chronic, Tendonitis Elbow, Tendonitis Shoulder, Tendonitis;Achilles, Tenosynovitis
- Interventions
- Artery Embolization
- Procedure
- Lead sponsor
- Vascular Solutions of North Carolina
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2029
- U.S. locations
- 2
- States / cities
- Cary, North Carolina • Winchester, Tennessee
- Conditions
- Healthy Participants
- Interventions
- Volitional Contractions (VOL), Neuromuscular Electrical Stimulation (NMES), Noxious Electrical Stimulation (NXES)
- Other · Device
- Lead sponsor
- University of New England
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Portland, Maine
- Conditions
- Pain, Back
- Interventions
- Auricular acupuncture, Visual Analog Scale for Pain, Roland-Morris Disability Questionnaire
- Device · Behavioral
- Lead sponsor
- Korey Kennelty
- Other
- Eligibility
- 18 Years to 115 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Vulvar Cancers, Vulva Neoplasm, Vulvar Dysplasia
- Interventions
- J-Tip, Lidocaine HCl 1%
- Device · Drug
- Lead sponsor
- Tufts Medical Center
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 106 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Collapse of Thoracic Vertebra, Collapse of Lumbar Vertebrae
- Interventions
- Dexmedetomidine
- Drug
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 142 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Opioid Use, Prescription Drug Abuse and Dependency, Surgery, Postoperative Pain
- Interventions
- No opioids at discharge
- Behavioral
- Lead sponsor
- Albany Medical College
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 350 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2024
- U.S. locations
- 1
- States / cities
- Albany, New York
- Conditions
- Low Back Pain, Myofascial Pain Syndrome Lower Back
- Interventions
- Treatment of Myofascial Pain Syndrome in the low back. This intervention will be based on outcomes of the medications listed below., Evaluation of functional ability using a patient centered functional score known as the Modified Oswestry Disability Index (MODI). The intervention will be based on outcomes of medications below., Following up with participants 60-72 hours after treatment in the Emergency Department. This intervention will be based on outcomes of the medications listed below.
- Drug
- Lead sponsor
- Madigan Army Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 180 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Tacoma, Washington
- Conditions
- Thyroid Eye Disease (TED), Graves Ophthalmopathy, Thyroid Associated Ophthalmopathies
- Interventions
- Smartphone-based AI self-monitoring application (Glandy CAS/EXO/LID)
- Device
- Lead sponsor
- THYROSCOPE INC.
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- San Jose, California
- Conditions
- Chronic Pain Syndrome, Chronic Daily Headache, Functional Abdominal Pain Syndrome, Musculoskeletal Pain Disorder, CRPS (Complex Regional Pain Syndromes)
- Interventions
- Offset analgesia
- Other
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 10 Years to 17 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Waltham, Massachusetts
- Conditions
- Migraine
- Interventions
- MRI, Thermal Stimuli, Pressure stimuli, Pain ratings, Pressure pain thresholds (PPT), Conditioned pain modulation (CPM) efficiency, Hormonal assessment, Migraine-related measures, Neural assessments, Pubertal status
- Device · Behavioral · Diagnostic Test
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 10 Years to 13 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2030
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Head and Neck Squamous Cell Carcinoma
- Interventions
- Buprenorphine, Tramadol, Oral Mucositis (OM) Pain App
- Drug · Device
- Lead sponsor
- Medical College of Wisconsin
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Opioid Tapering
- Interventions
- Treatment as Usual (TAU), Telephonic Support (TS) Providers, DOTS Intervention
- Other
- Lead sponsor
- Montefiore Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Contraception
- Interventions
- IUD insertion, Povidone-Iodine, Chlorhexidine, Oxygen, Nitrous oxide
- Procedure · Drug · Other
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 12 Years and older · Female only
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico