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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:49 AM EDT

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Showing 553–576 of 741 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Wake Clear all
Terminated No phase listed Observational Accepts healthy volunteers

Cerebral Blood Flow Evaluation With Trancranial Doppler After Interscalene Nerve Block

NCT04642612
View directory record Official record
Conditions
Regional Anesthesia, Horner Syndrome, Cerebral Blood Flow
Interventions
TCD Measurement
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2021 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Not applicable Interventional

Effect of Therapeutic Light on Sleep, Circadian Rhythm, and Global Function in Women With Alzheimer's

NCT02502045
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Morning Simulated Sunlight, Non-therapeutic Red Light
Device
Lead sponsor
Yale University
Other
Eligibility
65 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Farmington Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 20, 2017 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Deep Versus Awake Tracheal Extubation in Adults

NCT05361850
View directory record Official record
Conditions
Airway Complication of Anesthesia, Respiratory Complications of Care
Interventions
Extubation
Procedure
Lead sponsor
United States Navy
Federal
Eligibility
18 Years to 64 Years
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms

NCT05276739
View directory record Official record
Conditions
Light Exposure, Meal Timing
Interventions
Bright Light, Time-restricted eating, Dim light, 12-h meal window
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 30 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Not applicable Interventional

Electrophysiologic Changes in Blacks Treated With CBT for Insomnia

NCT02741336
View directory record Official record
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Self-Monitoring
Behavioral
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
30 Years to 50 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Oct 21, 2026, 4:49 AM EDT
Not listed Not applicable Interventional

Incentive Spirometry in Non-critically Ill Hospitalized Patients With Acute Respiratory Failure

NCT02873000
View directory record Official record
Conditions
Pulmonary Complication, Dyspnea, Pneumonia, COPD, CHF, Atelectasis, PE
Interventions
Incentive Spirometry
Behavioral
Lead sponsor
Jewish Hospital, Cincinnati, Ohio
Other
Eligibility
65 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 21, 2026, 4:49 AM EDT
Not listed Phase 2Phase 3 Interventional

Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Previously Untreated Corneal Ulcers

NCT05255107
View directory record Official record
Conditions
Keratitis, Corneal Ulcer
Interventions
Standard of Care Therapy + CXL + Riboflavin 0.23% L Solution, Standard of Care Therapy + Sham CXL + Artificial Tears
Combination Product · Other
Lead sponsor
Peschke GmbH
Industry
Eligibility
18 Years and older
Enrollment
468 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Littleton, Colorado • Fort Myers, Florida • Tampa, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2022 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Not applicable Interventional Results available

Sleep Extension or Regularity to Reduce Diabetes Risk

NCT06128265
View directory record Official record
Conditions
Overweight or Obesity
Interventions
Sleep Extension, Sleep Regularity
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 50 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Not applicable Interventional

The Effect of Maternal Scent on Sleep Wake States

NCT04301453
View directory record Official record
Conditions
Development, Infant
Interventions
Maternal Scent
Other
Lead sponsor
Columbia University
Other
Eligibility
30 Weeks to 36 Weeks
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 26, 2022 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Sleep Health, Inflammation, and Emotion Study

NCT02270619
View directory record Official record
Conditions
Depression
Interventions
Endotoxin, Partial sleep deprivation, Placebo, Uninterrupted sleep
Biological · Behavioral · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years to 80 Years · Female only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 18, 2021 · Synced Oct 21, 2026, 4:49 AM EDT
Terminated Phase 1 Interventional Results available

The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study

NCT05229653
View directory record Official record
Conditions
Endometriosis, Post Operative Pain
Interventions
Ketamine, Placebo
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Tolvaptan in Subjects With Chronic Kidney Disease Between Late Stage 2 to Early Stage 4 Due to Autosomal Dominant Polycystic Kidney Disease

NCT02160145
View directory record Official record
Conditions
Chronic Kidney Disease, Autosomal Dominant Polycystic Kidney Disease
Interventions
Tolvaptan (OPC-41061), Placebo
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
1,370 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
82
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 73 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Oct 21, 2026, 4:49 AM EDT
Completed No phase listed Observational

Awakening-Breathing Coordination, Delirium Monitoring/Management & Early Mobility (ABCDE) Protocol

NCT01413009
View directory record Official record
Conditions
ICU Delirium, Immobility
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 15, 2023 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Phase 2 Interventional Results available

Memory Improvement Through Nicotine Dosing (MIND) Study

NCT02720445
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Nicotine Transdermal Patch, Placebo Patch
Drug
Lead sponsor
University of Southern California
Other
Eligibility
55 Years to 90 Years
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
36
States / cities
Scottsdale, Arizona • North Little Rock, Arkansas • Downey, California + 31 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Light Treatment for Sleep/Wake Disturbances in Alzheimer's Disease

NCT00946530
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
Bright light, Control
Device
Lead sponsor
Stanford University
Other
Eligibility
55 Years to 100 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Microbiome and Resilience to Sleep and Circadian Disruption

NCT03747367
View directory record Official record
Conditions
Sleep Deprivation, Circadian Dysregulation, Stress
Interventions
Insufficient Sleep, Prebiotic, Placebo
Behavioral · Dietary Supplement
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 45 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 21, 2026, 4:49 AM EDT
Terminated Not applicable Interventional

Feasibility of Music Therapy for Spontaneous Breathing Trials

NCT05008328
View directory record Official record
Conditions
Spontaneous Breathing Trial, Intubation, Mechanical Ventilation, Music Therapy
Interventions
Music therapy plus standard care during an SBT, Standard care during an SBT
Other · Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 21, 2026, 4:49 AM EDT
Recruiting Not applicable Interventional

Decoding and Selective Modulation of Human Memory During Awake/Sleep Cycles

NCT05452122
View directory record Official record
Conditions
Memory, Delayed
Interventions
Auditory and Electrical Stimulation
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 21, 2026, 4:49 AM EDT
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Hand Sanitizer Use for Herpes Simplex Virus-1

NCT06135844
View directory record Official record
Conditions
Virus, HSV-1, Herpes Simplex 1, Herpes Simplex Labialis
Interventions
Purell Hand Sanitizer, Medical Grade Mineral Oil
Drug
Lead sponsor
Leciel Bono
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
3
States / cities
Pocatello, Idaho • St. George, Utah
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 21, 2026, 4:49 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Family-Based Meal Timing for Cancer Prevention Among Native Hawaiian and Other Pacific Islanders: FAMTIME

NCT07262593
View directory record Official record
Conditions
Cancer Prevention
Interventions
Time Restricted Eating (TRE), Medically Tailored Meals (MTM)
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 21, 2026, 4:49 AM EDT
Not listed Not applicable Interventional

Physical Activity and Quality of Life in Fibrotic Lung Diseases After Initiating Anti-fibrotic Therapy and Pulmonary Rehabilitation

NCT05866198
View directory record Official record
Conditions
Lung Diseases, Interstitial
Interventions
Actigraph CP Insight Watch
Diagnostic Test
Lead sponsor
University of South Florida
Other
Eligibility
40 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 15, 2023 · Synced Oct 21, 2026, 4:49 AM EDT
Recruiting Not applicable Interventional

Study of Enterra Programming with Nocturnal Cycling in Gastroparetics

NCT05980455
View directory record Official record
Conditions
Gastroparesis, Gastroparesis Nondiabetic, Gastroparesis Due to Diabetes Mellitus
Interventions
Enterra® Therapy System
Device
Lead sponsor
Enterra Medical, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Louisville, Kentucky • Coon Rapids, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Not applicable Interventional

Effect of Sleep on the Recovery of Patients Admitted to the ICU

NCT04111900
View directory record Official record
Conditions
Critical Illness, Circadian Dysregulation, Delirium
Interventions
Sleep/Circadian Friendly
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Simulated Dawn Med Students

NCT02088593
View directory record Official record
Conditions
Depression, Anxiety, Fatigue, Sleepiness, Sleep Disruption
Interventions
Simulated Dawn Light Box, Sleep Hygiene instructions
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Oct 21, 2026, 4:49 AM EDT