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ClinicalTrials.gov public records Last synced Oct 21, 2026, 8:01 AM EDT

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Showing 601–624 of 741 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Wake Clear all
Recruiting Not applicable Interventional

Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and Moderators

NCT04722341
View directory record Official record
Conditions
Colorectal Cancer, Breast Cancer
Interventions
Time-Restricted Eating (TRE), Control
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Birmingham, Alabama • West Hollywood, California
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 21, 2026, 8:01 AM EDT
Completed Phase 3 Interventional

Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)

NCT04652882
View directory record Official record
Conditions
Sleep Wake Disorders, Sleep Disorders, Circadian Rhythm, Chronobiology Disorders
Interventions
Tasimelteon, Placebo
Drug
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
11
States / cities
Los Angeles, California • Redwood City, California • Aurora, Colorado + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 21, 2026, 8:01 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Dose-dependent Impact of Daytime Lighting on Evening Responses to Light

NCT04882280
View directory record Official record
Conditions
Sleep
Interventions
Light
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2022 · Synced Oct 21, 2026, 8:01 AM EDT
Not yet recruiting Not applicable Interventional

Fitbit-Tracked Micromovement for Cardiometabolic Health in Rural Women

NCT07704749
View directory record Official record
Conditions
Cardiometabolic Risk Factors
Interventions
RISE-W Micro-Movement Program
Behavioral
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 21, 2026, 8:01 AM EDT
Completed Not applicable Interventional Results available

Clinical Assessment of a Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lens

NCT04476784
View directory record Official record
Conditions
Myopia
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
5
States / cities
Maitland, Florida • Bloomington, Illinois • Pittsburg, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2021 · Synced Oct 21, 2026, 8:01 AM EDT
Completed Phase 1 Interventional

Biomarkers of Fast Acting Therapies in Major Depression

NCT02165449
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Ketamine
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 64 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 21, 2026, 8:01 AM EDT
Recruiting Not applicable Interventional

Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia

NCT05527652
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hypertonia, Muscle, Nasal Airway Obstruction, Tolerance, Trisomy 21, Down Syndrome
Interventions
Self-Supporting Nasopharyngeal Airway (ssNPA)
Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 21 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 21, 2026, 8:01 AM EDT
Completed Phase 4 Interventional

Light Sedation or Intubated General Anesthesia in Patients With Brain Cancer Undergoing Craniotomy

NCT02193568
View directory record Official record
Conditions
Adult Brain Tumor
Interventions
Arm I (light sedation), Arm II (intubated general anesthesia), Arm II (intubated general anesthesia), Arm I (light sedation)
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
19 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Oct 21, 2026, 8:01 AM EDT
Completed Not applicable Interventional

Mindfulness Therapy on Disrupted Sleep in Bipolar Disorder

NCT01764035
View directory record Official record
Conditions
Bipolar Disorder, Insomnia, Hypersomnia, Sleep Problems
Interventions
Body Scan (BS) Meditation Intervention, Brief Supportive Psychotherapy (SP)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2016 · Synced Oct 21, 2026, 8:01 AM EDT
Completed No phase listed Observational

Using Smartphone Sensor Technology to Characterize Ambulatory Patterns of Participants With Peripheral Artery Disease

NCT04124315
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Accelerometry, Daynamica app
Other
Lead sponsor
University of Minnesota
Other
Eligibility
40 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 21, 2026, 8:01 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Does Circadian Misalignment Have Sex-Specific Effects on Metabolism?

NCT07441265
View directory record Official record
Conditions
Circadian Misalignment, Sex Differences
Interventions
Day shift, Night shift
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 40 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 21, 2026, 8:01 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

INSIGHT: Insomnia, Nightmares, and Sympathetic Hyperactivity Intervention

NCT07288593
View directory record Official record
Conditions
Nightmare, Insomnia, PTSD, TBI, Sleep Disorder (Disorder), REM Behavior Disorder
Interventions
NightWare smartwatch configured to detect physiological signs of sympathetic activation during sleep, such as heart-rate spikes and movement patterns., Sham (No Treatment)
Device
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 62 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Bethesda, Maryland • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 21, 2026, 8:01 AM EDT
Not listed No phase listed Observational

The PROGRAM-study: Awake Mapping Versus Asleep Mapping Versus No Mapping for Glioblastoma Resections

NCT04708171
View directory record Official record
Conditions
Glioblastoma
Interventions
Awake mapping under local anesthesia, Asleep mapping under general anesthesia, Resection under general anesthesia without mapping
Procedure
Lead sponsor
Erasmus Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
453 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
San Francisco, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2022 · Synced Oct 21, 2026, 8:01 AM EDT
Recruiting No phase listed Observational

Comparison of Two Sedation Regimens for Awake Fiberoptic Intubation

NCT05736198
View directory record Official record
Conditions
Awake Fiberoptic Intubation, Difficult Airway
Interventions
Dexmedetomidine
Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2034
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 21, 2026, 8:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Critical Smoke Alarm Characteristics to Awaken Children From Stage 4 Sleep

NCT01169155
View directory record Official record
Conditions
Smoke Inhalation Injury, Burns
Interventions
Smoke Alarm Stimuli
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
5 Years to 84 Years
Enrollment
834 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 5, 2019 · Synced Oct 21, 2026, 8:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults

NCT03751020
View directory record Official record
Conditions
Depression, Suicidality, Substance Abuse, HIV, Minority Stress
Interventions
Expressive Writing (EW) Intervention, Self-Affirmation (SA) Intervention, Control
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 29 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
3
States / cities
New Haven, Connecticut • Worcester, Massachusetts • Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 28, 2020 · Synced Oct 21, 2026, 8:01 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Automated Insulin Delivery in Elderly With Type 1 Diabetes (AIDE T1D)

NCT04016662
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Tandem t:slim X2 with HCL or PLGS
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
65 Years and older
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
4
States / cities
Orlando, Florida • Rochester, Minnesota • Syracuse, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Oct 21, 2026, 8:01 AM EDT
Recruiting Phase 3 Interventional

A Study to See if Tolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)

NCT04782258
View directory record Official record
Conditions
Autosomal Recessive Polycystic Kidney (ARPKD)
Interventions
Tolvaptan Suspension, Tolvaptan Tablets
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
28 Days to 18 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
12
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • Chicago, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 21, 2026, 8:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Light Timing Study

NCT04753190
View directory record Official record
Conditions
Chronobiology, Light, Sleep, Circadian Rhythm, Adolescence
Interventions
Baseline Sleep Satiation and Phase Stabilization, Gradually Shifted Sleep
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 20 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 21, 2026, 8:01 AM EDT
Withdrawn Phase 2 Interventional

Safety and Effectiveness Study of CPI-613 to Treat Refractory or Relapsed Leukemia and Myelodysplastic Syndrome

NCT01520805
View directory record Official record
Conditions
Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)
Interventions
CPI-613
Drug
Lead sponsor
Cornerstone Pharmaceuticals
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Cranbury, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 29, 2016 · Synced Oct 21, 2026, 8:01 AM EDT
Completed Phase 4 Interventional Results available

Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.

NCT02970669
View directory record Official record
Conditions
Heart Failure, Reduced Ejection Fraction
Interventions
sacubitril/valsartan (LCZ696), enalapril, matching placebo sacubitril/valsartan (LCZ696), matching placebo enalapril
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 80 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
23
States / cities
Fort Payne, Alabama • Beverly Hills, California • Stockton, California + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Oct 21, 2026, 8:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Detection of Sleep Stages and Arousals Using Neural Network Classifiers

NCT07136272
View directory record Official record
Conditions
Sleep Disordered Breathing (SDB), Sleep Apnea
Interventions
SSAM, Polysomnography, EnsoSleep
Device · Diagnostic Test
Lead sponsor
Pathway Medtech, LLC.
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
3
States / cities
Burlingame, California • Irvine, California • La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 21, 2026, 8:01 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

Northera Improves Postural Tachycardia Syndrome (POTS) and Postural Vasovagal Syncope (VVS)

NCT02558972
View directory record Official record
Conditions
Postural Tachycardia Syndrome (POTS), Vasovagal Syncope (VVS), Fainting
Interventions
Northera (Droxidopa), Placebo
Drug
Lead sponsor
New York Medical College
Other
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
Hawthorne, New York
Source: ClinicalTrials.gov public record
Updated May 23, 2025 · Synced Oct 21, 2026, 8:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of Light Therapy for Fatigue N-of-1 Trials

NCT04707846
View directory record Official record
Conditions
Fatigue
Interventions
Bright Blue Light Commercial AYO Light Therapy Device, Dim Blue Light Commercial AYO Light Therapy Device
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 59 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 21, 2026, 8:01 AM EDT