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Showing 1–24 of 317 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Weight Loss and Weight Maintenance Clear all
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Healthy Eating and Active Living Taught at Home (HEALTH) Dissemination & Implementation (D&I)

NCT03758638
View directory record Official record
Conditions
Obesity
Interventions
Healthy Eating & Active Living Taught at Home, Usual Care
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Financial Coaching and Lifestyle Intervention for Diabetes Prevention in Low-income Families

NCT05944549
View directory record Official record
Conditions
Weight Loss
Interventions
Financial coaching using TrustPlus, Brighter Bites, Noom
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Sep 26, 2026, 10:38 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Does Dapagliflozin Promote Favorable Health Benefits That Are Independent Of Weight Loss?

NCT02520518
View directory record Official record
Conditions
Weight Loss
Interventions
Dapagliflozin, Placebo, Weight maintenance, Ad libitum dietary intake, Dietary restriction
Drug · Behavioral
Lead sponsor
Christopher Bell
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 2, 2019 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Caloric Titration Method of Weight Loss and Maintenance

NCT03553160
View directory record Official record
Conditions
Healthy
Interventions
Frequent Self-Weighing
Other
Lead sponsor
Cornell University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Jun 11, 2018 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional

UPHS Weight Loss Study

NCT01800591
View directory record Official record
Conditions
Obesity
Interventions
Financial incentive
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 70 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2015 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimal Timing of Exercise Initiation Within a Lifestyle Weight Loss Program

NCT01985568
View directory record Official record
Conditions
Obesity
Interventions
Sequential BT, Standard BT
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 26, 2026, 10:38 AM EDT
Recruiting Not applicable Interventional

SMART to Optimize an Intervention to Maintain Health Improvements After Cardiac Rehabilitation

NCT06886789
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiac Rehabilitation
Interventions
Text Messaging, Fully Automated Online Program, Low-Intensity Cardiac Rehabilitation Maintenance Program, High Intensity Cardiac Rehabilitation Maintenance Program
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Phase 4 Interventional

Effects of Glucosamine and Chondroitin Supplementation in Women With Knee Osteoarthritis Participating in an Exercise and Weight Loss Program

NCT01271218
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Diet, Exercise
Other
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Jan 5, 2011 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Weight Loss on Hepatic and Muscle Lipid Content and on Insulin Sensitivity on Obese Adolescents With NAFLD

NCT00585299
View directory record Official record
Conditions
Fatty Liver, Insulin Resistance
Interventions
Low-fat diet, Traditional diet
Other
Lead sponsor
Yale University
Other
Eligibility
10 Years to 21 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 16, 2014 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Personalized Telehealth Intervention for Health and Weight Loss in Postpartum Women

NCT01751230
View directory record Official record
Conditions
Postpartum Weight Retention
Interventions
WIC E-Moms
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 23, 2021 · Synced Sep 26, 2026, 10:38 AM EDT
Completed No phase listed Observational

Energy Expenditure and Weight Loss Maintenance

NCT03422380
View directory record Official record
Conditions
Obesity, Weight Change, Body, Weight Loss, Physical Activity
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Timeline
2009 – 2012
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 4, 2018 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Parents and Children Together Preventing Diabetes (PACT PD)

NCT01819493
View directory record Official record
Conditions
Diabetes Prevention
Interventions
Lifestyle Intervention, Standard Family-Based intervention
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
8 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Sep 26, 2026, 10:38 AM EDT
Active, not recruiting Phase 3 Interventional

A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term

NCT07011667
View directory record Official record
Conditions
Obesity
Interventions
CagriSema (Cagrilintide B and Semaglutide I), Placebo matched to CagriSema (Cagrilintide B and Semaglutide I)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
609 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
46
States / cities
Costa Mesa, California • San Diego, California • Walnut Creek, California + 41 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 26, 2026, 10:38 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Blood Glucose Differences Between Left Arm and Right Arm Using a Continuous Glucose Monitor

NCT04102657
View directory record Official record
Conditions
Diabetes
Interventions
Intermittent Fasting, Free-Living Diet, Left Arm Exercise, Right Arm Exercise
Other
Lead sponsor
University of the Pacific
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Stockton, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Sep 26, 2026, 10:38 AM EDT
Active, not recruiting Not applicable Interventional

The Inspiring Action to Prevent Diabetes Intervention

NCT06001801
View directory record Official record
Conditions
PreDiabetes
Interventions
Diabetes Prevention Program, INSPIRA
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diabetes Prevention Program Pilot Study

NCT00729079
View directory record Official record
Conditions
Diabetes Prevention
Interventions
DPP
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 11, 2015 · Synced Sep 26, 2026, 10:38 AM EDT
Active, not recruiting Phase 2Phase 3 Interventional

GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot Trial

NCT06162715
View directory record Official record
Conditions
Severe Obesity, Obesity, BMI Greater Than 30
Interventions
Tirzepatide, Standard of Care post-gastric bypass
Drug · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
25 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional

A Test of Nutritional Interventions to Enhance Weight Loss Maintenance

NCT01065974
View directory record Official record
Conditions
Overweight, Obesity, Weight Loss Maintenance
Interventions
Behavior Therapy, Meal Replacements, Nutritrol
Behavioral · Dietary Supplement
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 65 Years
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 8, 2017 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance

NCT02380963
View directory record Official record
Conditions
Overweight, Obesity, Weight Loss
Interventions
Colorado Diet with soy protein foods., Colorado Diet with monetary payments
Dietary Supplement · Behavioral
Lead sponsor
DuPont Nutrition and Health
Industry
Eligibility
18 Years to 55 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 3, 2019 · Synced Sep 26, 2026, 10:38 AM EDT
Not listed Not applicable Interventional

Online Obesity Treatment in Primary Care (Rhode Island, USA)

NCT03488212
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Training to Identify Eligible Patients and Direct them to Online Obesity Treatment Program, Training to Motivate and Support Patients' Weight Loss, Online Behavioral Weight Loss Intervention, Control Intervention for Weight Loss Maintenance and Weight Gain Prevention, Monthly Lessons and Feedback Intervention for Weight Loss Maintenance and Weight Gain Prevention, Refresher Courses for Weight Loss Maintenance and Weight Gain Prevention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 19, 2020 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intermittent Fasting, Caloric Restriction and Body Composition in Obese Men and Women

NCT02525419
View directory record Official record
Conditions
Weight Loss
Interventions
Weight Loss Phase, HP-IF, HH
Behavioral
Lead sponsor
Skidmore College
Other
Eligibility
30 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Saratoga Springs, New York
Source: ClinicalTrials.gov public record
Updated Aug 23, 2015 · Synced Sep 26, 2026, 10:38 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Modifying Obesogenic Homes: Impact on Weight Maintenance

NCT00200330
View directory record Official record
Conditions
Obesity
Interventions
Behavioral weight loss treatment, Behavioral and home environment weight loss treatment
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 17, 2007 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional

EMPOWER Men to Reduce Weight and Inhibit Prostate Cancer Progression

NCT04266431
View directory record Official record
Conditions
Prostatic Neoplasm
Interventions
EMPOWER
Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

ForgIng New Paths to Prevent DIabeTes (FINDIT)

NCT02747108
View directory record Official record
Conditions
Prediabetes
Interventions
Blood Test Group Intervention, Brochure Group Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
315 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Sep 26, 2026, 10:38 AM EDT