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Showing 1–24 of 379 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Weight gain Clear all
Terminated Phase 2 Interventional Results available

Megestrol Acetate in Treating Weight Loss or Anorexia in Young Patients With Malignancies Who Are Undergoing Radiation Therapy and/or Chemotherapy

NCT01200602
View directory record Official record
Conditions
Anorexia, Weight Changes
Interventions
megestrol acetate, clinical observation
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
Up to 21 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 24, 2015 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Not applicable Interventional Results available

A Trial to Determine Weight Gain Benefits of Caloric Supplementation for NAS Infants

NCT04419857
View directory record Official record
Conditions
Neonatal Abstinence Syndrome
Interventions
High-calorie formula
Dietary Supplement
Lead sponsor
Yale University
Other
Eligibility
Not listed
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Balance: A Pragmatic Trial of a Digital Health Intervention to Prevent Weight Gain in Primary Care

NCT03003403
View directory record Official record
Conditions
Obesity, Overweight, Overnutrition, Nutrition Disorders, Signs and Symptoms
Interventions
Intervention Program
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
443 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treating Prediabetes in the First Trimester

NCT01926457
View directory record Official record
Conditions
Prediabetes, Gestational Diabetes
Interventions
Treatment of Prediabetes
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2018 · Synced Sep 11, 2026, 3:24 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Pedometer Use to Prevent Excessive Pregnancy Weight Gain in Overweight Women

NCT01469260
View directory record Official record
Conditions
Overweight, Obesity, Pregnancy
Interventions
Pedometer
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 20, 2021 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing the Feasibility and Preliminary Effect of Summer Camp

NCT04085965
View directory record Official record
Conditions
Childhood Obesity Prevention
Interventions
Boys and Girls Club summer day camp
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
6 Years to 12 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Naltrexone and Varenicline: Weight Gain and Tolerability in Cigarette Smokers

NCT00502216
View directory record Official record
Conditions
Smoking, Nicotine Dependence
Interventions
Naltrexone, Varenicline
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise-Based Obesity Simulation and Weight Bias

NCT07430891
View directory record Official record
Conditions
Weight Bias, Health Professions Education, Implicit Bias
Interventions
Exercise with Obesity Simulation Suit, Exercise-only, Control
Behavioral
Lead sponsor
University of Wisconsin, River Falls
Other
Eligibility
18 Years to 30 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
River Falls, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Phase 2 Interventional Results available

A Study to Assess the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adults With Schizophrenia or Bipolar Disorder Treated With Antipsychotic Medications

NCT03818256
View directory record Official record
Conditions
Antipsychotic-induced Weight Gain (AIWG)
Interventions
Miricorilant, Placebo
Drug
Lead sponsor
Corcept Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
27
States / cities
Bentonville, Arkansas • Little Rock, Arkansas • Culver City, California + 23 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparative Effectiveness Study Evaluating the Effects of Thermogenic Supplements on Body Composition

NCT01423019
View directory record Official record
Conditions
Weight Loss
Interventions
Advantra Z, Advantra Z + Naringin + Hesperiden, Sugar pill
Dietary Supplement · Other
Lead sponsor
Integrative Health Technologies, Inc.
Network
Eligibility
21 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2012 · Synced Sep 11, 2026, 3:24 PM EDT
Recruiting Not applicable Interventional

Open vs. Blind Weighing Study In Adolescents and Young Adult With Eating Disorders

NCT06085092
View directory record Official record
Conditions
Eating Disorders, Anorexia Nervosa
Interventions
Open weighing, Blind weighing
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
12 Years to 24 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparative Effectiveness of Adding Weight Control to Smoking Cessation Quitlines

NCT01867983
View directory record Official record
Conditions
Cigarette Smoking, Overweight, Obesity
Interventions
Weight gain prevention and smoking cessation, Smoking cessation
Behavioral
Lead sponsor
Consumer Wellness Solutions
Industry
Eligibility
18 Years and older
Enrollment
2,540 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Phase 4 Interventional Results available

Methylphenidate for the Treatment of Gait Impairment in Parkinson's Disease

NCT00526630
View directory record Official record
Conditions
Parkinson's Disease, Gait Impairment
Interventions
Methylphenidate (MPD), Placebo
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
35 Years to 85 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced Sep 11, 2026, 3:24 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Blossom Project: "BlossomUP" Methods to Decrease Sedentary Time in Pregnancy

NCT02909725
View directory record Official record
Conditions
Sedentary Lifestyle, Diabetes Mellitus, Gestational
Interventions
Limit accumulation of sedentary time, Walk, Normal daily routine; Usual Care
Other
Lead sponsor
Iowa State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Ames, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 20, 2016 · Synced Sep 11, 2026, 3:24 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Does Dietary and Lifestyle Counseling Prevent Excessive Weight Gain During Pregnancy? A Randomized Controlled Trial

NCT00792480
View directory record Official record
Conditions
Obesity, Pregnancy
Interventions
Dietary and lifestyle counseling
Behavioral
Lead sponsor
Carolinas Medical Center
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 17, 2008 · Synced Sep 11, 2026, 3:24 PM EDT
Active, not recruiting Phase 4 Interventional

Sequential Multiple Assignment Randomized Trial for Bipolar Depression

NCT06433635
View directory record Official record
Conditions
Bipolar I Disorder, Depression
Interventions
Cariprazine, Aripiprazole/Escitalopram combination, Quetiapine, Lurasidone
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
2,726 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
17
States / cities
Birmingham, Alabama • Bloomington, Indiana • Baltimore, Maryland + 13 more
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Not applicable Interventional

Impact of a Personal Digital Assistant (PDA) - Based Dietary Adherence Intervention on Interdialytic Weight Gain and Blood Pressure in Hemodialysis Patients

NCT00447408
View directory record Official record
Conditions
End-Stage Renal Disease
Interventions
Standard hemodialysis dietary instruction, Behavioral counseling plus PDA-based self-monitoring of diet
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 27, 2010 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Study of a Prebiotic Supplement to Mitigate Excessive Weight Gain Among Physicians in Residency

NCT04498455
View directory record Official record
Conditions
Weight Gain Trajectory, Metabolic Syndrome
Interventions
Prebiotin
Dietary Supplement
Lead sponsor
Baylor University
Other
Eligibility
Not listed
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Aug 16, 2020 · Synced Sep 11, 2026, 3:24 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Addressing Anxiety and Stress for Healthier Eating in Teens

NCT05038033
View directory record Official record
Conditions
Obesity, Overweight, Anxiety, Mental Disorders, Body Weight, Eating Behavior, Feeding and Eating Disorders
Interventions
Interpersonal Psychotherapy (IPT), Cognitive Behavioral Theory (CBT)
Behavioral
Lead sponsor
The Metis Foundation
Other
Eligibility
12 Years to 17 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Fort Collins, Colorado • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 7, 2021 · Synced Sep 11, 2026, 3:24 PM EDT
Terminated Not applicable Interventional

Pilot Study of Dietary Modification of Appetite Set Point in Obesity

NCT00726271
View directory record Official record
Conditions
Obesity
Interventions
light olive oil, fish oil capsules, flax seed oil capsules
Dietary Supplement
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Sep 11, 2026, 3:24 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Predictors of Maternal Weight Gain and Neonatal Body Composition

NCT00634764
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 17, 2018 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Excessive Gestational Weight Gain Via Short Mobile Messages in WIC

NCT04330976
View directory record Official record
Conditions
Gestational Weight Gain
Interventions
Nutrition and physical activity intervention, Control
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older · Female only
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Apr 1, 2020 · Synced Sep 11, 2026, 3:24 PM EDT
Completed Phase 2 Interventional Results available

Strategies to Reduce Antipsychotic-Associated Weight Gain in Youth

NCT00617240
View directory record Official record
Conditions
Weight Gain
Interventions
metformin, placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
10 Years to 17 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 10, 2014 · Synced Sep 11, 2026, 3:24 PM EDT
Completed No phase listed Observational

Investigation of Diagnostic Improvement Gained Through Optimization of MR Methods for Breast Cancer Detection

NCT02411760
View directory record Official record
Conditions
Breast Neoplasms
Interventions
3 Tesla Magnetic Resonance Imaging
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Sep 11, 2026, 3:24 PM EDT