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ClinicalTrials.gov public records Last synced Oct 17, 2026, 11:46 PM EDT

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Showing 865–888 of 893 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Weight loss diet Clear all
Recruiting Phase 2 Interventional

A Mobile Intervention to Reduce Pain and Improve Health-III

NCT06623669
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis, Obesity and Overweight, Inactivity
Interventions
MORPH, Measurement Only
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
65 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 17, 2026, 11:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing the Efficacy of a Spousal Support Enhanced Weight Loss Program on Weight Loss Among African American Men

NCT02458053
View directory record Official record
Conditions
Overweight, Weight Loss, Obese
Interventions
Attends with partner, Couples Skill Training, Face to face group sessions, Self Monitor, Notebook, Feedback
Behavioral · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 14, 2017 · Synced Oct 17, 2026, 11:46 PM EDT
Recruiting Phase 3 Interventional

AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

NCT07571005
View directory record Official record
Conditions
Obesity, Overweight, Obstructive Sleep Apnoea
Interventions
NNC0487-0111, Placebo (matched to NNC0487-0111)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
17
States / cities
San Diego, California • Miami, Florida • Naples, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 17, 2026, 11:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

New DIETs: New Dietary Interventions Enhancing the Treatment for Weight Loss

NCT01742572
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Diet
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 17, 2026, 11:46 PM EDT
Completed Not applicable Interventional

Development of a Telehealth Obesity Intervention for Patients With MS: Modifying Diet and Exercise in MS

NCT04255953
View directory record Official record
Conditions
Multiple Sclerosis, Obesity
Interventions
behavioral telehealth, Treatment as Usual
Behavioral · Other
Lead sponsor
Jared Bruce
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Oct 17, 2026, 11:46 PM EDT
Recruiting Not applicable Interventional

Remotely Delivered, Community-Aligned Weight Loss Interventions Among Breast Cancer Survivors, ¡Vida! Trial

NCT05930483
View directory record Official record
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
Interventions
¡Vida! program, ¡Vida! Plus [¡Vida! + Experiential Learning (EL)], Health Coaching, Mailed Toolkits
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
640 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 17, 2026, 11:46 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing Self-Monitoring Feedback Delivery for the Treatment of Overweight and Obesity

NCT07227051
View directory record Official record
Conditions
Obesity & Overweight, Obesity (Disorder)
Interventions
Feedback on Calorie Goal Attainment, Feedback on Dietary Quality, Feedback on Physical Activity Goal Attainment, Goal Setting Prompt
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 17, 2026, 11:46 PM EDT
Completed Phase 2 Interventional

WALNUTS for POWER: Polyphenols, Omega-3 Fatty Acids, Weight Loss, and EneRgy

NCT03824652
View directory record Official record
Conditions
Prostate Cancer
Interventions
walnuts, usual diet, phone counseling with dietitian
Other
Lead sponsor
Stephen Freedland
Other
Eligibility
18 Years and older · Male only
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 17, 2026, 11:46 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

CRAVE Study: Comparing Craving Responses and Diet Quality of GLP1 Receptor Agonist Users

NCT06467604
View directory record Official record
Conditions
Obesity
Interventions
Surveys, Indirect Calorimetry, Body composition, Anthropometrics
Behavioral · Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Needham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 17, 2026, 11:46 PM EDT
Completed Phase 4 Interventional Results available

Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects

NCT05548647
View directory record Official record
Conditions
Obesity
Interventions
Behavioral Treatment, Placebo, Semaglutide 2.4 MG/0.75 ML Subcutaneous Solution [WEGOVY]
Behavioral · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 17, 2026, 11:46 PM EDT
Completed Not applicable Interventional

Behavioral CVD Prevention Using Informatics

NCT02752464
View directory record Official record
Conditions
Health Behavior
Interventions
Counseling, feedback report
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Oct 17, 2026, 11:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Weight Loss on Hepatic and Muscle Lipid Content and on Insulin Sensitivity on Obese Adolescents With NAFLD

NCT00585299
View directory record Official record
Conditions
Fatty Liver, Insulin Resistance
Interventions
Low-fat diet, Traditional diet
Other
Lead sponsor
Yale University
Other
Eligibility
10 Years to 21 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 17, 2014 · Synced Oct 17, 2026, 11:46 PM EDT
Not listed Not applicable Interventional

Online Obesity Treatment in Primary Care (Rhode Island, USA)

NCT03488212
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Training to Identify Eligible Patients and Direct them to Online Obesity Treatment Program, Training to Motivate and Support Patients' Weight Loss, Online Behavioral Weight Loss Intervention, Control Intervention for Weight Loss Maintenance and Weight Gain Prevention, Monthly Lessons and Feedback Intervention for Weight Loss Maintenance and Weight Gain Prevention, Refresher Courses for Weight Loss Maintenance and Weight Gain Prevention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 20, 2020 · Synced Oct 17, 2026, 11:46 PM EDT
Active, not recruiting Not applicable Interventional

Fiber-rich Foods to Treat Obesity and Prevent Colon Cancer

NCT04780477
View directory record Official record
Conditions
Colon Cancer, Obesity
Interventions
High Fiber Diet Featuring Legumes (HLD), Healthy American Diet
Dietary Supplement
Lead sponsor
Emory University
Other
Eligibility
40 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 17, 2026, 11:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Medium Chain Triglyceride Oil, Versus Olive Oil, for Weight Loss

NCT00529919
View directory record Official record
Conditions
Overweight
Interventions
Weight loss
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 50 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 14, 2007 · Synced Oct 17, 2026, 11:46 PM EDT
Completed Not applicable Interventional Results available

ELIRA 2: Safety and Effectiveness of TENS Assisted Weight Loss and Appetite Suppression

NCT03936699
View directory record Official record
Conditions
Weight Loss
Interventions
Transcutaneous Nerve Stimulator (TENS), Diet & Exercise
Device · Behavioral
Lead sponsor
Elira Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Oct 17, 2026, 11:46 PM EDT
Completed Not applicable Interventional

A Remote Delivered Lifestyle Therapeutics Program

NCT04201028
View directory record Official record
Conditions
Body Weight Changes, Weight Loss, Healthy Diet, Obesity
Interventions
Video Conferencing Health Coaching with devices, Video Conferencing Health Coaching with no devices
Behavioral
Lead sponsor
Coastal Carolina University
Other
Eligibility
20 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Oct 17, 2026, 11:46 PM EDT
Recruiting Not applicable Interventional

Cooking Skills to Improve Long-Term Weight Loss in Young Adults With Intellectual Disabilities

NCT06961591
View directory record Official record
Conditions
Intellectual Disability, Overweight and Obesity
Interventions
Weight Loss Plus Cooking, Traditional Weight Loss
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 35 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 17, 2026, 11:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men

NCT04186260
View directory record Official record
Conditions
NAFLD
Interventions
NAFLD-specific weight loss intervention, Wait-list control
Behavioral · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 24, 2025 · Synced Oct 17, 2026, 11:46 PM EDT
Completed Not applicable Interventional

Problematic Decision-Making and Adolescent Weight Loss

NCT04848532
View directory record Official record
Conditions
Overweight Adolescents, Overweight or Obesity, Impulsive Behavior, Overeating
Interventions
Weight loss treatment
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
14 Years to 18 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 13, 2025 · Synced Oct 17, 2026, 11:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Based Treatment for Weight Loss With Breakfast Prescription

NCT02467036
View directory record Official record
Conditions
Obesity, Overweight, Overeating, Weight, Childhood Obesity
Interventions
Family Based Behavioral Treatment
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
8 Years to 12 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Oct 17, 2026, 11:46 PM EDT
Not yet recruiting Not applicable Interventional

Optimizing Adaptive Intensive Behavioral Therapy for Obesity During the Transition to Older Adulthood

NCT07446907
View directory record Official record
Conditions
Obesity & Overweight, Sarcopenia
Interventions
High Protein Diet Counceling, Standard Protein Diet Counceling, Protein Supplement, Supervised Exercise
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years to 75 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 17, 2026, 11:46 PM EDT
Recruiting Phase 3 Interventional

AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

NCT07720271
View directory record Official record
Conditions
Overweight, Obesity
Interventions
zenagamtide, Placebo
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
950 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
41
States / cities
Anniston, Alabama • Birmingham, Alabama • Montgomery, Alabama + 36 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 17, 2026, 11:46 PM EDT
Terminated Not applicable Interventional

Weight Loss in Pre-Hypertensive Patients With Diastolic Dysfunction

NCT00911209
View directory record Official record
Conditions
Obesity, Heart Disease, Weight Loss, Diastolic Dysfunction
Interventions
Dietitian counselling
Behavioral
Lead sponsor
Ragavendra Baliga
Other
Eligibility
21 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 15, 2012 · Synced Oct 17, 2026, 11:46 PM EDT