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ClinicalTrials.gov public records Last synced Oct 22, 2026, 1:02 AM EDT

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Showing 193–216 of 379 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Working Memory Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Non-invasive Nerve Stimulation and Cognitive Training to Improve Cognitive Performance in Healthy Older Adults

NCT04276805
View directory record Official record
Conditions
Aging
Interventions
Transcutaneous vagal nerve stimulation (tVNS), Cognitive training
Device · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 90 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
2
States / cities
Tucson, Arizona • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional Results available

Neurally Targeted Cognitive Training to Augment CBT Outcomes in Pediatric Anxiety

NCT04157296
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Cognitive behavioral therapy (CBT), computerized cognitive training (CCT)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
7 Years to 17 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Oct 22, 2026, 1:02 AM EDT
Active, not recruiting Not applicable Interventional

Training Response Artificial Intelligence Network (TRAIN)

NCT05903573
View directory record Official record
Conditions
Amnestic Mild Cognitive Impairment
Interventions
Cognitive Training, Computerized Cognitive Stimulation
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 100 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 22, 2026, 1:02 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

TMS in Preclinical and Prodromal AD: Modulation of Brain Networks and Memory

NCT04294888
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Aging
Interventions
repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
60 Years to 85 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 22, 2026, 1:02 AM EDT
Active, not recruiting Not applicable Interventional

Cognitive Screening Made Easy for PCPs - R33 Phase

NCT06162026
View directory record Official record
Conditions
Cognitive Impairment, Dementia, Mild, Cognitive Decline
Interventions
RACS app
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
60 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional Results available

Working Memory Training on Delay Discounting Among Cigarette Smokers

NCT05210608
View directory record Official record
Conditions
Tobacco Use Disorder/Cigarette Smoking
Interventions
Working Memory Training + Behavioral Intervention
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Oct 22, 2026, 1:02 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effects of THC on Emotional Memory Retrieval

NCT03471585
View directory record Official record
Conditions
Healthy
Interventions
THC, Placebo oral capsule
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 35 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Oct 22, 2026, 1:02 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Neurobiology of Nicotine and Non-nicotine Components of Tobacco Addiction

NCT01056926
View directory record Official record
Conditions
Smoking
Interventions
Quit smoking, Nicotine patch, Placebo Patch
Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Oct 22, 2026, 1:02 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Brain Areas Involved in Sound and Spoken Word Memory

NCT01375595
View directory record Official record
Conditions
Brain Mapping, Language Disorder, Adult, Healthy, Memory Disorder
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 22, 2026, 1:02 AM EDT
Recruiting Phase 2Phase 3 Interventional

Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)

NCT06273527
View directory record Official record
Conditions
Anxiety Disorders, Depression, Post Traumatic Stress Disorder
Interventions
COGENT, Sham Program
Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 55 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 24, 2025 · Synced Oct 22, 2026, 1:02 AM EDT
Terminated Not applicable Interventional

Memory Training and Neural Plasticity

NCT05380739
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Working Memory Training
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 22, 2026, 1:02 AM EDT
Recruiting Phase 2 Interventional

Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression

NCT06559826
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Ketamine, Psychotherapy
Drug · Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Oct 22, 2026, 1:02 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Dopaminergic Effects on Cortical Function in Tourette's (Levodopa Protocol)

NCT00634556
View directory record Official record
Conditions
Tourette Syndrome
Interventions
levodopa solution 2mg/ml for i.v. use, placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 12, 2018 · Synced Oct 22, 2026, 1:02 AM EDT
Not listed Phase 2 Interventional

Clinical Testing of a D1 Agonist for Cognitive Enhancement in Schizotypal Personality Disorder

NCT01466205
View directory record Official record
Conditions
Cognitive Impairments, Schizotypal Personality Disorder
Interventions
DAR-0100A, Placebo
Drug
Lead sponsor
Larry J. Siever
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 20, 2012 · Synced Oct 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

State Representation in Early Psychosis - Project 4

NCT05664594
View directory record Official record
Conditions
Psychosis, Schizophrenia, Schizophrenia Spectrum and Other Psychotic Disorders, Schizoaffective Disorder
Interventions
Computerized Cognitive Training
Device
Lead sponsor
University of Minnesota
Other
Eligibility
15 Years to 45 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 22, 2026, 1:02 AM EDT
Recruiting Not applicable Interventional

Retraining Neural Pathways Improves Cognitive Skills After A Mild Traumatic Brain Injury

NCT03655782
View directory record Official record
Conditions
MTBI - Mild Traumatic Brain Injury
Interventions
PATH + DigitMemory (DM) neurotraining
Behavioral
Lead sponsor
Perception Dynamics Institute
Industry
Eligibility
18 Years to 60 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
San Diego, California • Solana Beach, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 22, 2026, 1:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prenatal Drug Exposure: Effects on the Adolescent Brain and Behavior Development

NCT01020669
View directory record Official record
Conditions
Drug Abuse, Prenatal Drug Exposure
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
13 Years to 17 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 22, 2026, 1:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neuropsychiatric Evaluation of Healthy Volunteers and Adults With Schizophrenia

NCT00001323
View directory record Official record
Conditions
Brain Injury, Dementia, Healthy, Mental Disorder, Schizophrenia
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
810 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional

Feasibility and Efficacy of a Home-based, Computerized Cognitive Training Program in Pediatric Sickle Cell Disease

NCT02857023
View directory record Official record
Conditions
Anemia, Sickle Cell
Interventions
Cogmed RM
Behavioral
Lead sponsor
Steven J. Hardy
Other
Eligibility
7 Years to 16 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 23, 2018 · Synced Oct 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional

Older Adults, Methadone, and Cognitive Function

NCT07153029
View directory record Official record
Conditions
Opioid Use Disorder, Cognitive Ability General
Interventions
Smartphone based cognitive tasks
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
55 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional

tDCS and Cognitive Training in Active Duty Service Members With Mild TBI: A Pilot Study

NCT04925453
View directory record Official record
Conditions
Brain Concussion, Brain Trauma, Attention Concentration Difficulty, Brain Injuries, Brain Injuries, Traumatic, Neurocognitive Dysfunction, Attention Impaired, Memory Impairment, Mild Traumatic Brain Injury, Mild Cognitive Impairment
Interventions
active tDCS and cognitive training intervention, sham tDCS and cognitive training intervention
Combination Product
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 55 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Theta Connectivity in Working Memory

NCT05204381
View directory record Official record
Conditions
Executive Function
Interventions
Theta-frequency near-zero phase lag stimulation, Theta-frequency anti-synchrony stimulation, Arrhythmic near-zero phase lag stimulation, Arrhythmic independent stimulation, Alpha-frequency near-zero phase lag stimulation, Alpha-frequency anti-synchrony stimulation
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Oct 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional Results available

Comparative Effectiveness Research in Veterans With PTSD

NCT01928732
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Cognitive Processing Therapy (CPT), Prolonged Exposure (PE)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
916 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
18
States / cities
Tuscaloosa, Alabama • Phoenix, Arizona • Long Beach, California + 15 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Oct 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional

Transplant Wellness Clinic for Elderly or High Risk Patients Undergoing BMT

NCT04194840
View directory record Official record
Conditions
Stem Cell Transplant Complications, Myeloma, Lymphoma, Allogeneic and Autologous Stem Cell Transplant
Interventions
physical therapy consult, Cognitive Assessment, Cancer Aging Research Group (CARG) assessment, Medication Review, Nutrition assessment, Laboratory studies, Patient satisfaction questionnaire, Physician Questionnaire, Patient follow-up questionnaire
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Oct 22, 2026, 1:02 AM EDT