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Showing 1–24 of 46 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: air insufflation Clear all
Terminated Phase 3 Interventional Accepts healthy volunteers

Comparison of Adenoma Detection Rate Among Water, Carbon Dioxide and Air Methods of Minimal Sedation Colonoscopy

NCT01782014
View directory record Official record
Conditions
Screening Colonoscopy
Interventions
colonoscopy
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 80 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2016 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional

A Trial of Supplemental CO2 Versus Room Air in Percutaneous Endoscopic Gastrostomy

NCT02619656
View directory record Official record
Conditions
Pneumoperitoneum
Interventions
CO2 insufflation, Ambient air insufflation
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 1, 2015 · Synced Sep 5, 2026, 12:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparing Clinical Performance of Novice Trainee Endoscopists Using Conventional Air Insufflation Versus Warm Water Infusion Colonoscopy

NCT01482546
View directory record Official record
Conditions
Colonoscopy Education
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)

NCT01607255
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Indigo carmine, water (exchange) method, water (exchange) plus dye method, air method
Drug · Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 75 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Sep 5, 2026, 12:45 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Comparision of Air Versus CO2 for Distention During Sigmoidoscopy

NCT00771290
View directory record Official record
Conditions
Colorectal Surgery
Interventions
Air insufflation with standard endoscopy unit, CO2 insufflation for colonoscopy (special CO2 insufflation unit)
Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional

Carbon Dioxide Insufflation Versus Conventional Air Insufflation

NCT02790359
View directory record Official record
Conditions
Abdominal Pain
Interventions
Air, Carbon dioxide
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
8 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional

A Randomized Controlled Trial (RCT) of Carbon Dioxide Versus Air Insufflation During Endoscopic Retrograde Cholangiopancreatography (ERCP)

NCT00685386
View directory record Official record
Conditions
Cholestasis
Interventions
CO2 insufflation, Room air insufflation
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 23, 2013 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional

Water-aided Colonoscopy vs Air Insufflation Colonoscopy in Colorectal Cancer Screening

NCT02041507
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Adenomas, Colorectal Polyps, Pain
Interventions
Air insufflation method., Water Immersion method., Water Exchange method.
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
50 Years to 70 Years
Enrollment
1,224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2016 · Synced Sep 5, 2026, 12:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Laryngeal Mask Airway (LMA) Unique and the Air-Q Intubating Laryngeal Airway (ILA) in Pediatric Patients

NCT01314248
View directory record Official record
Conditions
Children
Interventions
each child will receive both the LMA and ILA
Device
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
6 Months to 36 Months
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 29, 2013 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional

Comparison of Methods to Distend the Colon During Insertion: CO2, Air Insufflation, Water-aided Colonoscopy

NCT01954862
View directory record Official record
Conditions
Pain, Colorectal Adenomas, Colorectal Cancer
Interventions
Air Insufflation method., CO2 insufflation, Water Immersion/CO2, Water Exchange/CO2, Water Immersion/AI, Water Exchange/AI
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
18 Years to 85 Years
Enrollment
624 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2014 · Synced Sep 5, 2026, 12:45 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Comparison Air Versus Carbon Dioxide Insufflation in Single Balloon Anterograde Enteroscopy

NCT03811522
View directory record Official record
Conditions
Carbon Dioxide Insufflation, Anterograde Single Balloon Enteroscopy
Interventions
carbon dioxide insufflation, Air insufflation
Other
Lead sponsor
North Eastern Ohio Gastroenterology and Endoscopy center
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Warren, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional Results available

Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant

NCT04541667
View directory record Official record
Conditions
Endoscopy
Interventions
Air, Carbon Dioxide
Other
Lead sponsor
University of Nebraska
Other
Eligibility
6 Months to 19 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional

U-POEM vs CO2-POEM

NCT06918730
View directory record Official record
Conditions
Esophageal Motility Disorders
Interventions
U-POEM, CO2-POEM
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional

Abortive Effect of an Ear Insufflator on Migraine

NCT02614378
View directory record Official record
Conditions
Migraine
Interventions
air insufflation, placebo
Procedure
Lead sponsor
Carrick Institute for Graduate Studies
Other
Eligibility
18 Years to 70 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Phoenix, Arizona • Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 13, 2016 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional Results available

ALS and Airway Clearance (ALSAC) Therapy

NCT04947436
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Respiratory Muscle Weakness
Interventions
High Frequency Chest Wall Oscillation, Mechanical insufflation/exsufflation
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Phase 2 Interventional Results available

Metoclopramide Versus Placebo for GJ Placement

NCT03331965
View directory record Official record
Conditions
Radiation Exposure, Enteral Nutrition
Interventions
Metoclopramide 5 MG/ML Injectable Solution, Saline
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 12, 2020 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional

Comparing the Adenoma Detection Rate With Air Insufflation, Water Immersion and Water Exchange

NCT01894191
View directory record Official record
Conditions
Adenoma
Interventions
Air insufflation, water immersion, Water exchange
Procedure
Lead sponsor
Dalin Tzu Chi General Hospital
Other
Eligibility
20 Years to 80 Years
Enrollment
651 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2016 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pathogenesis and Outcomes of Sleep Disordered Breathing in Chronic Obstructive Pulmonary Disease (COPD)

NCT01764165
View directory record Official record
Conditions
COPD
Interventions
Oxygen, High flow of room air
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 80 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 4, 2016 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional Results available

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures

NCT03430206
View directory record Official record
Conditions
Oxygen Deficiency, Desaturation of Blood, Hypoventilation, Anesthesia; Adverse Effect
Interventions
High-flow nasal cannula
Device
Lead sponsor
Stanford University
Other
Eligibility
Up to 18 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2020 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional

Comparing the ADR With Air Insufflation, Water Immersion and Water Exchange During Two-endoscopist Colonoscopy

NCT02737514
View directory record Official record
Conditions
Adenoma
Interventions
Air insufflation, water immersion, water exchange
Procedure
Lead sponsor
Dalin Tzu Chi General Hospital
Other
Eligibility
20 Years to 80 Years
Enrollment
371 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated May 28, 2020 · Synced Sep 5, 2026, 12:45 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparison of on Demand Sedation With Study Method Versus on Demand Sedation With Conventional Method for Performing Colonoscopy for Colorectal Cancer Screening and Surveillance

NCT00920751
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
Water infusion, Air insufflation
Procedure
Lead sponsor
East Bay Institute for Research and Education
Other
Eligibility
50 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Jun 14, 2009 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional

A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in Diagnostic Patients

NCT01781650
View directory record Official record
Conditions
Pain, Colorectal Adenomas, Colorectal Cancer
Interventions
Air Insufflation method., Water Immersion method., Water Exchange method.
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
18 Years to 85 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2014 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness and Safety of the Colonoscopy With "Visualization" Balloon

NCT02117232
View directory record Official record
Conditions
Colonic Adenomatous Polyps
Interventions
Visualization balloon, Traditional CO2 insufflation colonoscopy
Device
Lead sponsor
Mercy Medical Center
Other
Eligibility
17 Years to 90 Years
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Sep 5, 2026, 12:45 PM EDT
Completed Not applicable Interventional

Combined Chromoendoscopy and Water Method for Screening Colonoscopy

NCT01383265
View directory record Official record
Conditions
Colon Polyp
Interventions
Water method and chromoendoscopy, Water method
Procedure
Lead sponsor
VA Northern California Health Care System
Federal
Eligibility
50 Years to 75 Years
Enrollment
1,177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2013 · Synced Sep 5, 2026, 12:45 PM EDT