- Conditions
- Pulmonary Embolism
- Interventions
- Tenecteplase + Enoxaparin, 0.9% Saline + Enoxaparin
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 83 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 7
- States / cities
- Sacramento, California • Aurora, Colorado • Chicago, Illinois + 4 more
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–24
of 123
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Empyema, Pleural Effusion
- Interventions
- Alteplase
- Drug
- Lead sponsor
- O'Brien, Jeana D., MD, FACP, FCCP
- Individual
- Eligibility
- 18 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2004
- U.S. locations
- 1
- States / cities
- Temple, Texas
- Conditions
- Acute Ischemic Stroke
- Interventions
- Thrombolytic Agent
- Drug
- Lead sponsor
- Baylor College of Medicine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Pleural Effusion
- Interventions
- normal saline, TNK (Tenecteplase)
- Drug
- Lead sponsor
- Kaiser Permanente
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Honolulu, Hawaii
- Conditions
- Embolism, Thrombophlebitis
- Interventions
- Recombinant Tissue Plasminogen Activator, Heparin, Warfarin
- Drug
- Lead sponsor
- National Institutes of Health Clinical Center (CC)
- NIH
- Eligibility
- Not listed
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1998 – 2006
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Pleural Infection, Empyema, Pleural Diseases, Parapneumonic Effusion
- Interventions
- tissue plasminogen activator (tPA) and human recombinant deoxyribonuclease (DNase), Medical Thoracoscopy
- Drug · Procedure
- Lead sponsor
- Tulane University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- New Orleans, Louisiana
- Conditions
- Ischemic Stroke
- Interventions
- IV tpa (Alteplase) vs IA tpa (Alteplase)
- Drug
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2008
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Stroke
- Interventions
- 2-MHz transcranial Doppler ultrasound, 2-MHz transcranial Doppler ultrasound insonation
- Device
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2013
- U.S. locations
- 2
- States / cities
- Birmingham, Alabama • Houston, Texas
- Conditions
- Severe Acute Respiratory Syndrome, Respiratory Failure, Acute Respiratory Distress Syndrome
- Interventions
- Alteplase 50 MG [Activase]
- Drug
- Lead sponsor
- Denver Health and Hospital Authority
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 9
- States / cities
- La Jolla, California • Aurora, Colorado • Denver, Colorado + 5 more
- Conditions
- Ischemic Stroke
- Interventions
- Computed tomography perfusion imaging
- Other
- Lead sponsor
- California Pacific Medical Center Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2022
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Central Retinal Vein Occlusion
- Interventions
- Tissue Plasminogen Activator
- Drug
- Lead sponsor
- Weill Medical College of Cornell University
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Acute Submassive Pulmonary Embolism
- Interventions
- The Bashir™ Endovascular Catheter (BEC
- Device
- Lead sponsor
- Temple University
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Acute Ischemic Stroke
- Interventions
- MRX-801, Placebo
- Drug
- Lead sponsor
- ImaRx Therapeutics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 13
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Newport Beach, California + 9 more
- Conditions
- Congenital Heart Disease, Fibrinolysis, Rotational Thromboelastometry
- Interventions
- Intraoperative Blood Sample
- Other
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 2 Months to 12 Months
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Ischemic Stroke
- Interventions
- Alteplase (iv t-PA)
- Drug
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 3
- States / cities
- Birmingham, Alabama • Englewood, Colorado • Houston, Texas
- Conditions
- Pleural Effusion Associated With Pulmonary Infection, Bacterial Pleural Effusion Other Than Tuberculosis
- Interventions
- Alteplase, Placebo
- Drug
- Lead sponsor
- Midwest Pulmonary and Critical Care
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2009
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- Stroke
- Interventions
- Alteplase
- Drug
- Lead sponsor
- Thomas Jefferson University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2015
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Empyema
- Interventions
- tPA alone, tPA plus dornase
- Biological
- Lead sponsor
- Children's Mercy Hospital Kansas City
- Other
- Eligibility
- Up to 17 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Kansas City, Missouri
- Conditions
- Pulmonary Embolism and Thrombosis
- Interventions
- Ekosonic® Endovascular Device ultrasonic infusion catheter, Recombinant tissue plasminogen activator
- Device · Biological
- Lead sponsor
- Boston Scientific Corporation
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 131 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 16
- States / cities
- Beverly Hills, California • Tallahassee, Florida • Tampa, Florida + 13 more
- Conditions
- Acute Stroke
- Interventions
- IV rt-PA
- Drug
- Lead sponsor
- Lee Schwamm
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 14
- States / cities
- Tucson, Arizona • Los Angeles, California • Chicago, Illinois + 8 more
- Conditions
- Obesity
- Interventions
- Bradykinin
- Drug
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 13 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2011
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Thrombosis
- Interventions
- alteplase
- Drug
- Lead sponsor
- University of Louisville
- Other
- Eligibility
- 28 Weeks to 66 Weeks
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2012
- U.S. locations
- 1
- States / cities
- Louisville, Kentucky
- Conditions
- Acute Ischemic Stroke
- Interventions
- Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg)
- Drug
- Lead sponsor
- Memorial Hermann Health System
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Pleural Infection, Pleural Diseases
- Interventions
- Medical Thoracoscopy, Fibrinolytic Group
- Other
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts