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ClinicalTrials.gov public records Last synced Sep 22, 2026, 10:16 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: arthroplasty Clear all
Recruiting Not applicable Interventional

Zimmer Biomet Shoulder Arthroplasty PMCF

NCT04984291
View directory record Official record
Conditions
Shoulder Fractures, Shoulder Arthritis, Shoulder Osteoarthritis, Shoulder Deformity, Shoulder Injuries, Shoulder Pain
Interventions
Alliance Glenoid, Identity Stem
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
20 Years and older
Enrollment
584 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2033
U.S. locations
12
States / cities
Irvine, California • Golden, Colorado • Chicago, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 22, 2026, 10:16 PM EDT
Completed No phase listed Observational

Total Knee Arthroplasty Guidance Systems Study

NCT02830997
View directory record Official record
Conditions
Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
Interventions
Stereotactic guidance system
Device
Lead sponsor
Ormonde M. Mahoney, MD
Other
Eligibility
45 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 19, 2022 · Synced Sep 22, 2026, 10:16 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Longitudinal Assessment of Cartilage Injury and Remodeling After Anterior Cruciate Ligament Rupture and Reconstruction:

NCT03497780
View directory record Official record
Conditions
ACL - Anterior Cruciate Ligament Rupture, ACL Injury, Healthy
Interventions
Anterior cruciate ligament reconstruction
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 30 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Sep 22, 2026, 10:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epsilon Aminocaproic Acid (EACA) for the Reduction of Blood Loss in Total Hip Arthroplasty (THA)

NCT01391182
View directory record Official record
Conditions
Degenerative Joint Disease, Osteoarthritis
Interventions
EACA, Placebo arm
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 25, 2015 · Synced Sep 22, 2026, 10:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating the Need for Pneumatic Compression Devices

NCT02641080
View directory record Official record
Conditions
Osteoarthritis
Interventions
Aspirin, Portable Compression Device
Drug · Device
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Sep 22, 2026, 10:16 PM EDT
Completed Not applicable Interventional

Postoperative Hip Precautions After Total Hip Arthroplasty Via the Posterior Approach: A Prospective Randomized Trial

NCT02686528
View directory record Official record
Conditions
Osteoarthritis, Degenerative Joint Disease
Interventions
Hip Precautions, No Hip Precautions
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 22, 2026, 10:16 PM EDT
Completed Not applicable Interventional

Continuous Adductor Canal Block (CACB) vs. Combined Spinal Epidural (CSE) in Total Knee Arthroplasty

NCT02415465
View directory record Official record
Conditions
Arthroplasty
Interventions
Continuous Adductor Canal Block, General, Epidural, Spinal
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Sep 22, 2026, 10:16 PM EDT
Completed No phase listed Observational

Prediction of Outcomes Following Total Knee Replacement

NCT01370421
View directory record Official record
Conditions
Osteoarthritis
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
45 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 1, 2022 · Synced Sep 22, 2026, 10:16 PM EDT
Terminated No phase listed Observational

A Validated Necrosis Assay to Determine the Need for Revision Surgery in Metal-on-metal Total Hip Arthroplasty

NCT02208271
View directory record Official record
Conditions
Arthritis, Failure of Total Hip
Interventions
Not listed
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 22, 2026, 10:16 PM EDT
Completed Phase 3 Interventional Results available

Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block With EXPAREL in Shoulder Surgery

NCT02713230
View directory record Official record
Conditions
Pain
Interventions
bupivacaine liposome injectable suspension, Placebo
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
17
States / cities
Mobile, Alabama • Englewood, Colorado • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Sep 22, 2026, 10:16 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Tourniquet Pressure in Primary Total Knee Arthroplasty

NCT02830087
View directory record Official record
Conditions
Tourniquets, Knee Arthroplasty, Total, Knee Replacement, Total
Interventions
Tourniquet Cuff Pressure
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
2
States / cities
Bermuda Run, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Sep 22, 2026, 10:16 PM EDT
Completed Not applicable Interventional

Lumbar Plexus Block Versus Quadratus Lumborum Block for Primary Anterior Total Hip Arthroplasty

NCT03409900
View directory record Official record
Conditions
Osteoarthritis, Total Hip Arthroplasty
Interventions
LPB, QLB
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 95 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Sep 22, 2026, 10:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation

NCT00760383
View directory record Official record
Conditions
Osteoarthritis
Interventions
Essential amino acids, Alanine
Dietary Supplement
Lead sponsor
University of Oregon
Other
Eligibility
60 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
2
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 3, 2014 · Synced Sep 22, 2026, 10:16 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Navio Robotic Versus Conventional Total Knee Arthroplasty

NCT03519269
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Navio™ Robotics-assisted Surgical System
Device
Lead sponsor
Columbia University
Other
Eligibility
40 Years to 85 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 22, 2026, 10:16 PM EDT
Terminated No phase listed Observational

Outcomes Study of the TM Humeral Stem Used in Primary, Total or Hemi Shoulder Arthroplasty

NCT01480453
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Ununited Humeral Head Fracture, Irreducible 3- and 4-part Proximal Humeral Fractures, Avascular Necrosis
Interventions
Trabecular Metal Humeral Stem
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
3
States / cities
Louisville, Kentucky • Royal Oak, Michigan • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 25, 2019 · Synced Sep 22, 2026, 10:16 PM EDT
Enrolling by invitation Phase 4 Interventional

Comparison of Suzetrigine and Oxycodone for Postoperative Pain After Primary Total Knee Arthroplasty

NCT07219888
View directory record Official record
Conditions
Osteoarthritis (OA) of the Knee
Interventions
oral suzetrigine, oral Oxycodone
Drug
Lead sponsor
University of Louisville
Other
Eligibility
21 Years to 89 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 22, 2026, 10:16 PM EDT
Completed Not applicable Interventional

Gait Analysis of Anterior Versus Posterior Approach in Performance of Total Hip Arthroplasty

NCT00951951
View directory record Official record
Conditions
Osteoarthritis
Interventions
Anterior Approach, Posterior Approach
Procedure
Lead sponsor
Medacta USA
Industry
Eligibility
40 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
4
States / cities
Surprise, Arizona • Fresno, California • Lone Tree, Colorado + 1 more
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Sep 22, 2026, 10:16 PM EDT
Enrolling by invitation Not applicable Interventional

The Use of Smart Glasses for Saphenous Nerve Adductor Canal Block

NCT07213622
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Smartglasses
Procedure
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Sep 22, 2026, 10:16 PM EDT
Completed No phase listed Observational

RISC Panel Remnant Sample Collection

NCT05778162
View directory record Official record
Conditions
Arthritis, Inflammatory
Interventions
Synovasure® RISC™ Panel
Diagnostic Test
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 89 Years
Enrollment
1,000 participants
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Sep 22, 2026, 10:16 PM EDT
Recruiting Not applicable Interventional

Proximal FEmur Reconstruction or Internal Fixation fOR Metastases (PERFORM) Trial

NCT06863129
View directory record Official record
Conditions
Metastatic Bone Disease
Interventions
Internal Fixation, Resection and reconstruction
Procedure
Lead sponsor
Michelle Ghert, MD
Other
Eligibility
18 Years and older
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
7
States / cities
Aurora, Colorado • Fort Wayne, Indiana • Baltimore, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 22, 2026, 10:16 PM EDT
Recruiting Phase 2 Interventional

A Study on TLC590 for Managing Postsurgical Pain

NCT06574269
View directory record Official record
Conditions
Postsurgical Pain Management
Interventions
TLC590, Ropivacaine
Drug
Lead sponsor
TLC Biopharmaceuticals, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Bellaire, Texas • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 22, 2026, 10:16 PM EDT
Completed Phase 4 Interventional Results available

Dronabinol in Total Knee Arthroplasty (TKA)

NCT04734080
View directory record Official record
Conditions
Total Knee Arthroplasty, Opioid Use
Interventions
Dronabinol 5mg Cap, Placebo oral tablet
Drug · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 70 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 22, 2026, 10:16 PM EDT
Recruiting No phase listed Observational

Improving Rehabilitation for Veterans After Total Knee Arthroplasty Using Individualized Recovery Trajectories

NCT05288803
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Clinical decision support tool (CDS tool)
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 90 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 22, 2026, 10:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

RCT Foley Catheter Study for Elective TJA

NCT05428020
View directory record Official record
Conditions
Postoperative Urinary Retention, Total Hip Arthroplasty, Total Knee Arthroplasty
Interventions
Indwelling foley catheter, No foley catheter
Device · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
388 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Sep 22, 2026, 10:16 PM EDT