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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:28 PM EDT

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Showing 313–336 of 371 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: ascorbic acid Clear all
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Respiratory and Autonomic Plasticity Following Intermittent Hypoxia

NCT00860743
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
Antioxidant cocktail
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 40 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 1, 2017 · Synced Oct 20, 2026, 5:28 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain

NCT00631111
View directory record Official record
Conditions
Pain
Interventions
effervescent ibuprofen tablets, effervescent Aspirin plus Vitamin C tablets, ibuprofen tablets, placebo
Drug
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
16 Years to 40 Years
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2009 · Synced Oct 20, 2026, 5:28 PM EDT
Terminated Phase 1 Interventional

Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma

NCT02833701
View directory record Official record
Conditions
Glioblastoma, Glioma
Interventions
Ascorbic Acid, Bevacizumab, Laboratory Biomarker Analysis, Quality-of-Life Assessment
Dietary Supplement · Biological · Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 24, 2023 · Synced Oct 20, 2026, 5:28 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Local Vasoconstriction in Postural Tachycardia Syndrome

NCT01210430
View directory record Official record
Conditions
Postural Tachycardia Syndrome
Interventions
Losartan, Ascorbic Acid (Vitamin C), Normal Saline
Drug
Lead sponsor
New York Medical College
Other
Eligibility
14 Years to 29 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Hawthorne, New York
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Oct 20, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Broccoli Seed Extract and Skin Health

NCT05745636
View directory record Official record
Conditions
Skin Inflammation
Interventions
Broccoli, mustard, vitamin C, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
25 Years to 57 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 20, 2023 · Synced Oct 20, 2026, 5:28 PM EDT
Recruiting Phase 3 Interventional

Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant

NCT05654922
View directory record Official record
Conditions
Pre-Bronchiolitis Obliterans Syndrome
Interventions
ARINA-1, Standard of care only
Drug · Other
Lead sponsor
Renovion, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
22
States / cities
Phoenix, Arizona • Los Angeles, California • San Diego, California + 17 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 20, 2026, 5:28 PM EDT
Completed Phase 2 Interventional Results available

Therapeutic Use of Intravenous Vitamin C in Allogeneic Stem Cell Transplant Recipients

NCT03613727
View directory record Official record
Conditions
Lymphoid Leukemia, Myeloid Leukemia, Monocytic Leukemia, Myelodysplasia
Interventions
Intravenous (IV) and oral Vitamin C
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 77 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 20, 2026, 5:28 PM EDT
Completed Phase 2 Interventional

Antioxidant Therapy in Lean and Obese Asthmatics

NCT01317563
View directory record Official record
Conditions
Asthma
Interventions
Vitamins A, E, C & Selenium, Placebo
Dietary Supplement
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
12 Years to 25 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 22, 2016 · Synced Oct 20, 2026, 5:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Developing a Nutritional Supplement to Increase Collagen Synthesis in People

NCT06138106
View directory record Official record
Conditions
Dietary Supplements, Connective Tissue, Exercise
Interventions
Natural Product Supplement, Placebo control
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 20, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessment of a Pre-Workout Dietary Supplement

NCT02952014
View directory record Official record
Conditions
Dietary Modification
Interventions
C4 Extreme, C4 Extreme (without Advantra Z, Placebo
Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years to 40 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Nov 2, 2016 · Synced Oct 20, 2026, 5:28 PM EDT
Completed Phase 2Phase 3 Interventional

Integrative Medicine Approach to the Management of Asthma in Adults

NCT00843544
View directory record Official record
Conditions
Asthma
Interventions
Integrative Medicine
Behavioral
Lead sponsor
Beth Israel Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2009 · Synced Oct 20, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

RCT of an Oral Acne Supplement for Adult Women

NCT06097871
View directory record Official record
Conditions
Acne
Interventions
Skin Nutraceutical Supplement, Placebo pill
Dietary Supplement · Other
Lead sponsor
Nutraceutical Wellness Inc.
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Oct 20, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treatment of Non-Anemic Iron Deficiency in Pregnancy

NCT05423249
View directory record Official record
Conditions
Non-anemic Iron Deficiency
Interventions
Ferrous sulfate, Prenatal, Docusate Sodium, Ascorbic Acid 500Mg Tab, Placebo
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
3
States / cities
Bohemia, New York • Commack, New York • East Setauket, New York
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 20, 2026, 5:28 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

The Effects of Vitamin E and Vitamin C and Exercise

NCT01369043
View directory record Official record
Conditions
Exercise and Non-exercise Effect Upon Vitamins E and C
Interventions
Vitamin E and Vitamin C
Dietary Supplement
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
30 Years to 50 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Mar 9, 2015 · Synced Oct 20, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Zinc Versus Multivitamin Micronutrient Supplementation in the Setting of COVID-19

NCT04551339
View directory record Official record
Conditions
Healthy, Health Care Worker Patient Transmission, Aging
Interventions
PreserVision AREDS formulation soft gels or tablets, Multivitamin with 11mg of zinc
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
2,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Oct 20, 2026, 5:28 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Investigating the Wrinkle Reduction Potential of a Novel Compounded Skin Care Cream

NCT03878381
View directory record Official record
Conditions
Skin Care
Interventions
Skin Care Cream, Placebo
Combination Product · Drug
Lead sponsor
Wayne State University
Other
Eligibility
20 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dearborn, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Oct 20, 2026, 5:28 PM EDT
Completed No phase listed Observational

Outcomes of Septic Shock Patients Treated With a Metabolic Resuscitation Bundle Consisting of Intravenous Hydrocortisone, Ascorbic Acid and Thiamine.

NCT03913468
View directory record Official record
Conditions
Septic Shock, Ascorbic Acid Deficiency
Interventions
Intravenous Ascorbic Acid
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 90 Years
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 14, 2021 · Synced Oct 20, 2026, 5:28 PM EDT
Recruiting No phase listed Observational

Testosterone Deficiency and Endothelial Dysfunction After Spinal Cord Injury

NCT07227740
View directory record Official record
Conditions
Spinal Cord Injuries, Endothelial Dysfunction, Testosterone Deficiency
Interventions
Intra-arterial Infusion of Vasoactive Agents, Intra-arterial Vitamin C Infusion, Blood Sampling
Diagnostic Test
Lead sponsor
Craig Hospital
Other
Eligibility
18 Years to 89 Years · Male only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 20, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Impact of Qualia Vitamin C+ on Blood Vitamin C Levels

NCT07285109
View directory record Official record
Conditions
Healthy, Suboptimal Vitamin C Levels
Interventions
Qualia Vitamin C+, Placebo
Dietary Supplement
Lead sponsor
Qualia Life Sciences
Industry
Eligibility
25 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Carlsbad, California
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 20, 2026, 5:28 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Prospective Study of Topical Vitamin C (THDA) Versus Topical Vitamin C (THDA) With Acetyl Zingerone

NCT05779280
View directory record Official record
Conditions
Wrinkle, Skin Pigmentation
Interventions
THDA + Acetyl Zingerone Topical Product, THDA
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
30 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 25, 2023 · Synced Oct 20, 2026, 5:28 PM EDT
Completed Phase 1 Interventional

Burn Micronutrient Repletion Pilot Study

NCT00879723
View directory record Official record
Conditions
Burn
Interventions
Vitamin and Mineral supplementation
Dietary Supplement
Lead sponsor
Southern Illinois University
Other
Eligibility
19 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Springfield, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 26, 2015 · Synced Oct 20, 2026, 5:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1

NCT04916327
View directory record Official record
Conditions
Peripheral Vascular Diseases
Interventions
Antioxidant, Placebo
Dietary Supplement
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 35 Years
Enrollment
720 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 20, 2026, 5:28 PM EDT
Terminated Phase 2 Interventional Results available

Clinical Trial of High-dose Vitamin C for Advanced Pancreatic Cancer

NCT01515046
View directory record Official record
Conditions
Pancreatic Neoplasms, Pancreatic Cancer
Interventions
Gemcitabine with escalating ascorbic acid
Drug
Lead sponsor
Joseph J. Cullen
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Oct 20, 2026, 5:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vascular Function and Oxidative Stress in Emergency Medical Responders

NCT06985394
View directory record Official record
Conditions
Cardiovascular Function in EMTs
Interventions
Antioxidant cocktail, Placebo
Dietary Supplement
Lead sponsor
University of Delaware
Other
Eligibility
20 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Oct 20, 2026, 5:28 PM EDT