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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional

Computer-assisted Cognitive-Behavior Therapy for Depression in Primary Care

NCT02700009
View directory record Official record
Conditions
Depression
Interventions
Computer-assisted CBT (CCBT), Treatment as Usual (TAU)
Behavioral · Other
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Phase 4 Interventional Results available

SSRI Effects on Depression and Immunity in HIV/AIDS

NCT02620150
View directory record Official record
Conditions
Depression, HIV, AIDS
Interventions
Escitalopram, Placebo
Drug · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 70 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Not applicable Interventional Results available

Veteran Peer-Assisted Computerized Cognitive Behavioral Therapy for Depression

NCT02057042
View directory record Official record
Conditions
Depression
Interventions
Peer-assisted computerized CBT, Enhanced usual care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
3
States / cities
Ann Arbor, Michigan • Battle Creek, Michigan • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 10, 2019 · Synced Sep 7, 2026, 2:49 PM EDT
Not yet recruiting Not applicable Interventional

Supported Online Self-Help for Veterans With Depression in Primary Care

NCT07781228
View directory record Official record
Conditions
Depression
Interventions
Enhanced Usual Care (EUC), Supported Online Self-help for Depression (SOS-Depression)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
San Diego, California • West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Digital Cognitive Behavior Therapy Program for Suicide Prevention

NCT03595254
View directory record Official record
Conditions
Suicidal Ideation, Depression, Anxiety
Interventions
Thrive
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
18 Years and older
Enrollment
725 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Sep 1, 2020 · Synced Sep 7, 2026, 2:49 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression

NCT06375083
View directory record Official record
Conditions
Suicide, Depression
Interventions
c-CBT for Suicide Prevention, c-CBT or Depression
Behavioral
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 65 Years
Enrollment
472 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Not applicable Interventional Results available

Improving Depression Management

NCT05050227
View directory record Official record
Conditions
Depression
Interventions
cCBT Enhanced Collaborative Care, Usual Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2025 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Computerized Cognitive Behavioral Therapy for Childhood Anxiety in Community Health Centers

NCT01416805
View directory record Official record
Conditions
Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder
Interventions
Computerized Cognitive Behavioral Therapy, Treatment as usual
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 13 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
4
States / cities
Clearwater, Florida • Fort Lauderdale, Florida • Pensacola, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2019 · Synced Sep 7, 2026, 2:49 PM EDT
Recruiting Not applicable Interventional

Multisite Advancement of Research on Chronic Posttraumatic Headache

NCT05620719
View directory record Official record
Conditions
Posttraumatic Headache
Interventions
Cognitive Behavioral Therapy for Posttraumatic Headache, Treatment as Usual, Telemedicine-based Cognitive Behavioral Therapy (TCBT)
Behavioral · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 70 Years
Enrollment
525 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
8
States / cities
Los Angeles, California • Palo Alto, California • Honolulu, Hawaii + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer- Assisted Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders

NCT01565629
View directory record Official record
Conditions
Autism, Asperger's Syndrome, Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder, Obsessive-compulsive Disorder
Interventions
Computer assisted cognitive behavioral therapy.
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 12 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Oct 25, 2017 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Not applicable Interventional

Computerized Cognitive Behavior Therapy in Treating Depression in Patients With Cancer

NCT02837887
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Computerized Cognitive Behavior Therapy
Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 21, 2020 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Not applicable Interventional

Computerized Cognitive Behavioral Therapy Assisted Life Management for Pain in Sickle Cell Disease

NCT03029468
View directory record Official record
Conditions
Sickle Cell Disease, Chronic Pain
Interventions
cognitive behavioral therapy, eEducation
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computerized Cognitive Behavioral Treatment for Insomnia: Improving Rural Veteran Access to Evidence-Based Treatment to Reduce Suicide Risk (R-Vets Sleep)

NCT03365024
View directory record Official record
Conditions
Insomnia, Mental Health Functioning, Physical Health Functioning
Interventions
Computerized Cognitive Behavioral Therapy for Insomnia, Sleep Education
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of a Computerized Cognitive Behavioral Treatment for Insomnia: Increasing Access to Insomnia Treatment to Decrease Suicide Risk

NCT03366870
View directory record Official record
Conditions
Insomnia, Physical Health Functioning, Mental Health Functioning
Interventions
Computerized Cognitive Behavioral Therapy for Insomnia, Sleep Education
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 30, 2020 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Neural Circuit Biomarkers of Major Depression Response to CCBT

NCT03096886
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Depressive Disorder, Depression, Unipolar
Interventions
Computer-Augmented Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Not applicable Interventional

Cognitive Behavioral Therapy and Real-time Self-management Intervention for SCD Via Mobile Applications

NCT02384590
View directory record Official record
Conditions
Sickle Cell Disease, Depression, Anxiety
Interventions
Computerized cognitive behavioral therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 24, 2017 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Phase 2Phase 3 Interventional

Online Treatments for Mood and Anxiety Disorders in Primary Care

NCT01482806
View directory record Official record
Conditions
Depression, Generalized Anxiety Disorder, Panic Disorder
Interventions
CCBT+ISG/Collaborative Care, CCBT/Collaborative Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 75 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2020 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Not applicable Interventional Results available

Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell Via Mobile Applications

NCT04419168
View directory record Official record
Conditions
Chronic Pain, Depression, Anxiety, Opioid Use
Interventions
cCBT, m-Education
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
359 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
7
States / cities
Chicago, Illinois • Baltimore, Maryland • Durham, North Carolina + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced Sep 7, 2026, 2:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Thrive, a Computerized Cognitive Behavior Therapy Program to Treat Depression

NCT03244878
View directory record Official record
Conditions
Depressive Symptoms
Interventions
Thrive
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
18 Years and older
Enrollment
464 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Aug 13, 2018 · Synced Sep 7, 2026, 2:49 PM EDT
Recruiting Not applicable Interventional

Comparing Acoustic Resonance Therapy (ART) vs. Cognitive Behavioral Therapy for Insomnia (CBT-I)

NCT07486882
View directory record Official record
Conditions
Chronic Insomnia Disorder
Interventions
Mayo Clinic Cognitive Behavioral Therapy for Insomnia (CBT-I), Acoustic Resonance Therapy (ART)
Behavioral · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
22 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 7, 2026, 2:49 PM EDT