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Showing 1–24 of 56 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Accepts healthy volunteers

Interaction Effects of Temperature and Ozone

NCT01981135
View directory record Official record
Conditions
Exposure to Environmental Pollution, Non-occupational
Interventions
Clean Air, Ozone
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 55 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 9, 2015 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Phase 4 Interventional Results available

A Study to Evaluate the Efficacy and Safety of a Leave-in Spray in Subjects With Head Lice Infestation

NCT05565820
View directory record Official record
Conditions
Pediculosis Capitis, Lice Infestations, Head Lice
Interventions
Vamousse Spray 'n' Go, Nix Creme Rinse Lice Treatment
Other · Drug
Lead sponsor
Alliance Pharmaceuticals
Industry
Eligibility
2 Years to 75 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 23, 2025 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional Results available

Promoting Risk Reduction Among Young Adults With Asthma During Wildfire Smoke Events (TRAK)

NCT04724733
View directory record Official record
Conditions
Asthma
Interventions
Smoke Sense, Smoke Sense Plus
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years to 26 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Human Perception of Odors and Odor Blockers

NCT06191419
View directory record Official record
Conditions
Tobacco Smoking, Smoking Behaviors
Interventions
Odorants
Other
Lead sponsor
Tim McClintock
Other
Eligibility
18 Years to 60 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epigenetic Effects of Diesel Exhaust and Ozone Exposure

NCT01492517
View directory record Official record
Conditions
Exposure to Pollution, Inhalation of Ozone
Interventions
Ozone exposure, Diesel exhaust, Ozone18, Clean Air
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 55 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 17, 2016 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect Of Obesity On Ozone-Induced Airway Inflammation

NCT00839943
View directory record Official record
Conditions
Obesity
Interventions
ozone, 0.4 ppm
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 26, 2012 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of Cecal Intubation Rates and Pain Levels Between Water Exchange and Air Insufflation Flexible Sigmoidoscopy

NCT03209349
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Water Exchange Sigmoidoscopy, Air Insufflation Sigmoidoscopy
Procedure
Lead sponsor
Kelowna Gastroenterology Associates
Other
Eligibility
50 Years to 74 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2022 · Synced Sep 3, 2026, 5:37 PM EDT
Recruiting Not applicable Interventional

Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study

NCT07196436
View directory record Official record
Conditions
Asthma Control, Pulmonary Function, Quality of Life, Stress, Sleep Quality
Interventions
Energy Recovery Ventilator, Portable Air Cleaner, Energy Recovery Ventilator (Sham), Portable Air Cleaner (Sham)
Device
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
5 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Arlington, Texas • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional

Physiological Changes in Adults With Metabolic Syndrome Exposed to Ultrafine Air Particles

NCT01475968
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Ultrafine Air Pollution Particulate Matter, Filtered Air
Other
Lead sponsor
David Diaz-Sanchez
Federal
Eligibility
25 Years to 70 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2013
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 6, 2013 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional

Unsedated Colonoscopy for Colorectal Cancer Screening and Surveillance

NCT01383252
View directory record Official record
Conditions
Colon Polyp
Interventions
Water infusion in lieu of air insufflation, Air method
Procedure
Lead sponsor
VA Northern California Health Care System
Federal
Eligibility
50 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2013 · Synced Sep 3, 2026, 5:37 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Secondhand Effects of Hookah (i.e., Waterpipe) Smoke and Aerosol

NCT04661683
View directory record Official record
Conditions
Hookah Smoking, Secondhand Aerosol, Vascular Stiffness, Vaping
Interventions
Combustible Hookah Smoke, Electronic Hookah Aerosol, Clean Room Air
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 49 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Diesel Exhaust Followed by Administration of Nasal Spray Flu Vaccine on Individuals With & Without Allergies

NCT00617110
View directory record Official record
Conditions
Allergic Rhinitis
Interventions
live attenuated influenza virus (LAIV) with clean air, LAIV and diesel exhaust particles
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Sep 3, 2026, 5:37 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Pulmonary and Inflammatory Responses Following Exposure to a Low Concentration of Ozone or Clean Air

NCT05680831
View directory record Official record
Conditions
Lung Injury, Acute, Symptoms and Signs, Neutrophilia Acute
Interventions
0.070 ppm ozone concentration, Clean air (0.0 ppm ozone)
Biological
Lead sponsor
Martin W. Case
Federal
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 10, 2023 · Synced Sep 3, 2026, 5:37 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Clean Air Study: HEPA Purifiers to Improve Indoor Air Quality and Health in Rural Alaska Homes

NCT06534385
View directory record Official record
Conditions
Air Pollution, Indoor
Interventions
Air purifier
Device
Lead sponsor
Alaska Native Tribal Health Consortium
Other
Eligibility
Up to 5 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bethel, Alaska
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional

A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in Diagnostic Patients

NCT01781650
View directory record Official record
Conditions
Pain, Colorectal Adenomas, Colorectal Cancer
Interventions
Air Insufflation method., Water Immersion method., Water Exchange method.
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
18 Years to 85 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2014 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ozone Cardiovascular Effects in Genetically Susceptible People

NCT01192477
View directory record Official record
Conditions
Healthy
Interventions
Ozone
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 3, 2013 · Synced Sep 3, 2026, 5:37 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Woodsmoke Exposure, Influenza Infection, and Nasal Immunity

NCT06841913
View directory record Official record
Conditions
Smoke Exposure, Influenza
Interventions
LAIV nasal vaccine is chosen as a model viral infection, Wood smoke, Placebo for LAIV nasal vaccine is chosen as a model viral infection, Placebo for Wood Smoke (clean Air Exposure)
Biological · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 49 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 3, 2026, 5:37 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Lotrafilcon B Plano Cosmetic Contact Lenses Study

NCT06493383
View directory record Official record
Conditions
Cosmetic Appearance
Interventions
Lotrafilcon B plano cosmetic contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
12 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wildfire Related Air Pollution Exposure and Cognitive Function Pilot Study

NCT07151235
View directory record Official record
Conditions
Healthy Participants
Interventions
Simulated wildfire smoke exposure, Clean Air exposure
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 3, 2026, 5:37 PM EDT
Enrolling by invitation Not applicable Interventional

Efficacy of Non-surgical and Surgical Surface Decontamination Methods on Peri-implantitis-affected Implants

NCT06430268
View directory record Official record
Conditions
Peri-Implantitis, Dental Implant Failed
Interventions
implant decontamination with titanium curette, implant decontamination with Air-Flow device
Procedure · Device
Lead sponsor
Andrea Ravida
Other
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional

Acupuncture for the Prevention of Emergence Delirium in Children Undergoing Myringotomy Tube Placement

NCT02383004
View directory record Official record
Conditions
Delirium, Psychomotor Agitation
Interventions
Acupuncture
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
1 Year to 6 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 17, 2017 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Interaction of Social Factors With Air Pollution

NCT02206750
View directory record Official record
Conditions
Exposure to Environmental Pollution, Non-occupational
Interventions
Clean Air, Ozone
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 33 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 25, 2017 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products

NCT01964807
View directory record Official record
Conditions
Adverse Effect of Other Agents Primarily Affecting the Cardiovascular System, Initial Encounter
Interventions
Cigarette, NIDA test type with 16.6 mg nicotine, Cigarette, NIDA test type with <0.45 mg nicotine, Electronic cigarette with 18 mg/ml nicotine, Electronic Cigarette with no nicotine, Moist snuff, Sham Smoking, Secondhand cigarette smoke (SHS), Conditioned, filtered air, Sham Moist Snuff
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 50 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 26, 2021 · Synced Sep 3, 2026, 5:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epigenetic Effect Modifications With Ozone Exposure on Healthy Volunteers

NCT02469428
View directory record Official record
Conditions
Exposure to Environmental Pollution, Non-occupational
Interventions
Clean air, Ozone
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Sep 3, 2026, 5:37 PM EDT