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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)

NCT01607255
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Indigo carmine, water (exchange) method, water (exchange) plus dye method, air method
Drug · Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 75 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional

A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in CRC Screening

NCT01780818
View directory record Official record
Conditions
Pain, Colorectal Adenomas, Colorectal Cancer
Interventions
Air Insufflation method., Water Immersion method., Water Exchange method.
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
50 Years to 70 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2014 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epigenetic Effect Modifications With Ozone Exposure on Healthy Volunteers

NCT02469428
View directory record Official record
Conditions
Exposure to Environmental Pollution, Non-occupational
Interventions
Clean air, Ozone
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional

A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in Diagnostic Patients

NCT01781650
View directory record Official record
Conditions
Pain, Colorectal Adenomas, Colorectal Cancer
Interventions
Air Insufflation method., Water Immersion method., Water Exchange method.
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
18 Years to 85 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2014 · Synced Sep 26, 2026, 2:17 AM EDT
Enrolling by invitation Not applicable Interventional

Efficacy of Non-surgical and Surgical Surface Decontamination Methods on Peri-implantitis-affected Implants

NCT06430268
View directory record Official record
Conditions
Peri-Implantitis, Dental Implant Failed
Interventions
implant decontamination with titanium curette, implant decontamination with Air-Flow device
Procedure · Device
Lead sponsor
Andrea Ravida
Other
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 26, 2026, 2:17 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

BATokines as Biomarkers of Brown Fat in Humans

NCT05050240
View directory record Official record
Conditions
Healthy Lifestyle
Interventions
Cooling Vest Procedure, Fasting overnight
Other
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 28 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epigenetic Effects of Diesel Exhaust and Ozone Exposure

NCT01492517
View directory record Official record
Conditions
Exposure to Pollution, Inhalation of Ozone
Interventions
Ozone exposure, Diesel exhaust, Ozone18, Clean Air
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 55 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 17, 2016 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional Results available

Promoting Risk Reduction Among Young Adults With Asthma During Wildfire Smoke Events (TRAK)

NCT04724733
View directory record Official record
Conditions
Asthma
Interventions
Smoke Sense, Smoke Sense Plus
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years to 26 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Human Biological Responses to Low Level Ozone

NCT02857283
View directory record Official record
Conditions
Environmental Exposure, Nasal Inflammation
Interventions
Ozone, Filtered Air, Health and Exposure Tracker (HET)
Other · Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Sequential Exposure to Nitrogen Dioxide and Ozone in Healthy Adult Human Volunteers.

NCT02133586
View directory record Official record
Conditions
Respiratory Depression
Interventions
Ozone, Nitrogen dioxide
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 40 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 16, 2020 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effects of Wood Smoke Particles on Influenza-induced Nasal Inflammation in Normal Volunteers

NCT02183753
View directory record Official record
Conditions
Response of Viral Infection to Woodsmoke
Interventions
wood smoke, clean air
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 40 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2015 · Synced Sep 26, 2026, 2:17 AM EDT
Recruiting Not applicable Interventional

Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study

NCT07196436
View directory record Official record
Conditions
Asthma Control, Pulmonary Function, Quality of Life, Stress, Sleep Quality
Interventions
Energy Recovery Ventilator, Portable Air Cleaner, Energy Recovery Ventilator (Sham), Portable Air Cleaner (Sham)
Device
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
5 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Arlington, Texas • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional

Water-aided Colonoscopy vs Air Insufflation Colonoscopy in Colorectal Cancer Screening

NCT02041507
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Adenomas, Colorectal Polyps, Pain
Interventions
Air insufflation method., Water Immersion method., Water Exchange method.
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
50 Years to 70 Years
Enrollment
1,224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2016 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional

Impact of Carbon Dioxide Insufflation and Water Exchange on Post-Colonoscopy Outcomes

NCT02409979
View directory record Official record
Conditions
Abdominal Pain
Interventions
Carbon dioxide method, Water Exchange-CO2, Water Exchange-AI
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
18 Years to 80 Years
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 4, 2015 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional Results available

Evaluating the Effect of Tooth Cleaning Devices on Oral Health

NCT01250769
View directory record Official record
Conditions
Dental Plaque
Interventions
Manual Toothbrush, Interproximal Cleaning Device
Device
Lead sponsor
Philips Oral Healthcare
Industry
Eligibility
18 Years to 70 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 18, 2012 · Synced Sep 26, 2026, 2:17 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Secondhand Effects of Hookah (i.e., Waterpipe) Smoke and Aerosol

NCT04661683
View directory record Official record
Conditions
Hookah Smoking, Secondhand Aerosol, Vascular Stiffness, Vaping
Interventions
Combustible Hookah Smoke, Electronic Hookah Aerosol, Clean Room Air
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 49 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 26, 2026, 2:17 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Efficacy of Respiratory Protection Against the Effects of Wood Smoke Exposure in Young Healthy Adults

NCT06066749
View directory record Official record
Conditions
Healthy
Interventions
Filtration of all PM and VOC's, Filtration of VOC's
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of Cecal Intubation Rates and Pain Levels Between Water Exchange and Air Insufflation Flexible Sigmoidoscopy

NCT03209349
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Water Exchange Sigmoidoscopy, Air Insufflation Sigmoidoscopy
Procedure
Lead sponsor
Kelowna Gastroenterology Associates
Other
Eligibility
50 Years to 74 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2022 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Air Pollution Study: The Effect of Ozone on the Lung

NCT02673775
View directory record Official record
Conditions
Air Pollution
Interventions
Clean Air, Ozone
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 40 Years
Enrollment
135 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Sep 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional

Unsedated Colonoscopy for Colorectal Cancer Screening and Surveillance

NCT01383252
View directory record Official record
Conditions
Colon Polyp
Interventions
Water infusion in lieu of air insufflation, Air method
Procedure
Lead sponsor
VA Northern California Health Care System
Federal
Eligibility
50 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2013 · Synced Sep 26, 2026, 2:17 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Graded Exercise Hypoxia Testing

NCT06901284
View directory record Official record
Conditions
Hypoxia
Interventions
Graded Exercise Test, Graded Hypoxia Exercise Test
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 26, 2026, 2:17 AM EDT
Recruiting Not applicable Interventional

Peri-implantitis Management: Surgical and Maintenance Outcomes

NCT07550127
View directory record Official record
Conditions
Peri-implantitis
Interventions
Resective surgery with implantoplasty, Resective surgery with mechanical debridement
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 26, 2026, 2:17 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Lotrafilcon B Plano Cosmetic Contact Lenses Study

NCT06493383
View directory record Official record
Conditions
Cosmetic Appearance
Interventions
Lotrafilcon B plano cosmetic contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
12 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Sep 26, 2026, 2:17 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Role of Macrophage Activation in Lung Injury Following Ozone Exposure

NCT05794087
View directory record Official record
Conditions
Air Pollution
Interventions
Clean Air, Ozone
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 40 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 26, 2026, 2:17 AM EDT