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ClinicalTrials.gov public records Last synced Oct 17, 2026, 6:49 AM EDT

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Showing 721–744 of 1,231 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: congestive heart failure patients Clear all
Completed No phase listed Observational

A Real-world Study to Compare the Effectiveness of Sacubitril/Valsartan Versus ACEi/ARB in HFrEF Patients

NCT07376265
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
1,249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 17, 2026, 6:49 AM EDT
Terminated Not applicable Interventional

Randomized Trial for Patients With Chronic Heart Failure With Acute Decompensation

NCT00357591
View directory record Official record
Conditions
Heart Failure, Congestive
Interventions
Continuous Aortic Flow Augmentation
Device
Lead sponsor
Orqis Medical Corporation
Industry
Eligibility
18 Years to 90 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 25, 2009 · Synced Oct 17, 2026, 6:49 AM EDT
Not listed Phase 1 Interventional

Cardiac MRI for Optimal Heart Failure Outcomes With CRT Upgrades

NCT03504891
View directory record Official record
Conditions
Chronic Systolic Heart Failure, Paroxysmal VT
Interventions
MRI prior to CRT Upgrade, MRI prior to de novo CRT
Diagnostic Test
Lead sponsor
University of Virginia
Other
Eligibility
25 Years to 89 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 3, 2018 · Synced Oct 17, 2026, 6:49 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

COPILOT-HF: Cooperative Program for ImpLementation of Optimal Therapy in Heart Failure

NCT05734690
View directory record Official record
Conditions
Heart Failure
Interventions
SGLT2i, beta blocker, ARNI, MRA, MTD, Education-First
Drug · Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
503 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 17, 2026, 6:49 AM EDT
Withdrawn No phase listed Observational

Cardiac Compass With Optivol® to Negate Future Inpatient Re-admissions Through Monitoring in HF Patients (CONFIRM-HF)

NCT02026635
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 6, 2015 · Synced Oct 17, 2026, 6:49 AM EDT
Recruiting Not applicable Interventional

Tier - Palliative Care For Patients With Advanced Heart Failure or Cancer

NCT06228209
View directory record Official record
Conditions
Advanced Heart Failure, Advanced Non-Colorectal Gastointestinal Cancer, Advanced Lung Cancer
Interventions
Tier-Palliative Care
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 17, 2026, 6:49 AM EDT
Not listed Not applicable Interventional

Feasibility Study of the Intravascular Ventricular Assist System (iVAS)

NCT02645539
View directory record Official record
Conditions
Heart Failure NYHA Class III, Heart Failure NYHA Class IV
Interventions
intravascular ventricular assist system (iVAS)
Device
Lead sponsor
NuPulseCV
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
18
States / cities
Washington D.C., District of Columbia • Orlando, Florida • Chicago, Illinois + 14 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Oct 17, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

Patient and Family Partners in Heart Failure Care: Pilot Test of a Pre-visit Question Prompt List to Enhance Engagement During Medical Visits

NCT03491800
View directory record Official record
Conditions
Heart Failure
Interventions
Question/Topic Prompt List
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
30 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Oct 17, 2026, 6:49 AM EDT
Terminated Phase 2 Interventional

Oral Tonapofylline (BG9928) in Patients With Heart Failure and Renal Insufficiency

NCT00745316
View directory record Official record
Conditions
Renal Insufficiency, Heart Failure
Interventions
Tonapofylline, Placebo
Drug
Lead sponsor
Biogen
Industry
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
30
States / cities
Huntsville, Alabama • Mobile, Alabama • Scottsdale, Arizona + 25 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2023 · Synced Oct 17, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

Does Outpatient Palliative Care Improve Patient-centered Outcomes in Parkinson's Disease?

NCT02533921
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Interdisciplinary outpatient palliative care, Standard of Care
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
San Francisco, California • Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 31, 2020 · Synced Oct 17, 2026, 6:49 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

MRI Assessment of Patient Suitability for Cardiac Resynchronization Therapy (CRT)

NCT02728336
View directory record Official record
Conditions
Cardiac Resynchronization Therapy, Magnetic Resonance Imaging (MRI)
Interventions
Cardiac MRI
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 17, 2026, 6:49 AM EDT
Completed Phase 2 Interventional

Nesiritide and Vo2 Max in Heart Failure Patients

NCT00240084
View directory record Official record
Conditions
Heart Failure
Interventions
nesiritide (Natrecor(TM))
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 19, 2013 · Synced Oct 17, 2026, 6:49 AM EDT
Terminated Not applicable Interventional

Risk and Benefit Informed MTM Pharmacist Intervention in Heart Failure

NCT03804606
View directory record Official record
Conditions
Heart Failure
Interventions
Referral to MTM Pharmacist
Other
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 17, 2026, 6:49 AM EDT
Completed Not applicable Interventional

A Trial to Evaluate Medically Tailored Meals With Patients With Heart Failure

NCT04289181
View directory record Official record
Conditions
Heart Failure
Interventions
Medically Tailored Meals
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
50 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Oct 17, 2026, 6:49 AM EDT
Completed No phase listed Observational

Readmission Risk Factors and Heart Failure With Preserved Ejection Fraction

NCT04008914
View directory record Official record
Conditions
Heart Failure, Preserved Ejection Fraction
Interventions
retrospective observation
Other
Lead sponsor
Ascension Macomb-Oakland Hospital
Other
Eligibility
Not listed
Enrollment
492 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Warren, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 8, 2019 · Synced Oct 17, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

Study of Reminding to Improve Medication Adherence in Heart Failure

NCT01463267
View directory record Official record
Conditions
Heart Failure
Interventions
iPhone or pillbox, Non-reminding
Device · Behavioral
Lead sponsor
Kent State University
Other
Eligibility
45 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 27, 2020 · Synced Oct 17, 2026, 6:49 AM EDT
Active, not recruiting Not applicable Interventional

Evaluating the Reach of Clinical Decision Support for Patients With Heart Failure

NCT06847906
View directory record Official record
Conditions
Decision Support Systems, Clinical, Heart Failure
Interventions
Iteratively designed (new) clinical decision support tool for virtual visits, Traditional clinical decision support tool
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 17, 2026, 6:49 AM EDT
Recruiting Not applicable Interventional

Olive Oil Supplementation for Heart Failure With Reduced Ejection Fraction

NCT07644806
View directory record Official record
Conditions
Heart Failure With Reduced Ejection Fraction (HFrEF)
Interventions
Extra-virgin olive oil
Other
Lead sponsor
Old Dominion University
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 17, 2026, 6:49 AM EDT
Completed No phase listed Observational Results available

PARTNERS HF: Program to Access and Review Trending Information and Evaluate Correlation to Symptoms in Patients With Heart Failure

NCT00279955
View directory record Official record
Conditions
Heart Failure, Congestive
Interventions
Cardiac Resynchronization Therapy Device
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
1,024 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
93
States / cities
Huntsville, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 90 more
Source: ClinicalTrials.gov public record
Updated Jun 15, 2012 · Synced Oct 17, 2026, 6:49 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Role of Endothelin in Pulmonary Hypertension

NCT00759408
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
BQ-123
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 27, 2018 · Synced Oct 17, 2026, 6:49 AM EDT
Not listed Not applicable Interventional

A Trial of a CPR Video in Heart Failure Patients

NCT01653938
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
video decision aid
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
65 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Oct 17, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

Insomnia Self-Management in Heart Failure

NCT02660385
View directory record Official record
Conditions
Cardiac Failure, Heart Failure, Congestive Heart Failure, Heart Failure, Congestive, Sleep Initiation and Maintenance Disorders, Chronic Insomnia, Disorders of Initiating and Maintaining Sleep, Fatigue, Pain, Depressive Symptoms, Sleep Disorders, Anxiety
Interventions
Cognitive Behavioral Therapy for Insomnia, Self-Management Education for Heart Failure
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Oct 17, 2026, 6:49 AM EDT
Completed Phase 4 Interventional

Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure

NCT00115726
View directory record Official record
Conditions
Hypertension, Hypotension, Edema, Congestive Heart Failure
Interventions
furosemide, placebo
Drug
Lead sponsor
University of Calgary
Other
Eligibility
18 Years and older
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2007
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 22, 2008 · Synced Oct 17, 2026, 6:49 AM EDT
Completed Phase 2 Interventional Results available

Spironolactone in Adult Congenital Heart Disease

NCT01069510
View directory record Official record
Conditions
Congenital Heart Disease, Heart Failure, Endomyocardial Fibrosis
Interventions
Spironolactone 25mg, Placebo
Drug · Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Oct 17, 2026, 6:49 AM EDT