- Conditions
- Draining Hematoma
- Interventions
- Standard Pressure Dressing, VAC
- Procedure · Device
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 94 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2007
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
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Showing 1–24
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- Conditions
- Orthopaedic Traumatic Open Fractures
- Interventions
- Standard Wound Dressing, VAC
- Procedure · Device
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2010
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Periprosthetic Joint Infection
- Interventions
- Single Debridement, Antibiotics and Implant Retention, Planned Double Debridement, Antibiotics and Implant Retention
- Procedure
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 490 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2032
- U.S. locations
- 2
- States / cities
- Jacksonville, Florida • Rochester, Minnesota
- Conditions
- Torn Meniscus
- Interventions
- Mechanical Debridement, Paragon T2, Lavage debridement, RF- based Debridement
- Device · Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 165 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 10
- States / cities
- Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 6 more
- Conditions
- Diabetic Foot Ulcer
- Interventions
- SECONDARY dressing gauze and tape, debridement, irrigation, Dermagraft, Oasis
- Device · Procedure
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2018
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Prosthetic-joint Infection
- Interventions
- VT-X7 Treatment System, Two-stage exchange arthroplasty, SOC Antibiotics, Experimental Antibiotics
- Combination Product · Procedure · Drug
- Lead sponsor
- Osteal Therapeutics, Inc.
- Industry
- Eligibility
- 22 Years to 84 Years
- Enrollment
- 76 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 19
- States / cities
- Phoenix, Arizona • Los Angeles, California • Sarasota, Florida + 15 more
- Conditions
- Chronic Sinusitis, Ethmoidal
- Interventions
- Steroid-eluting sinus implant, Post-op standard of care
- Combination Product · Other
- Lead sponsor
- Collin County Ear Nose & Throat
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Frisco, Texas
- Conditions
- Open tíbia Fracture
- Interventions
- Antibiotic Cement Bead Pouch, Negative Pressure Wound Therapy
- Drug · Device
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 312 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 30
- States / cities
- Chandler, Arizona • Tucson, Arizona • Davis, California + 25 more
- Conditions
- Joint Infection
- Interventions
- Intraoperative Intraosseous Vancomycin
- Drug
- Lead sponsor
- OrthoCarolina Research Institute, Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2027
- U.S. locations
- 10
- States / cities
- San Francisco, California • Gainesville, Florida • Weston, Florida + 5 more
- Conditions
- Wound Infection
- Interventions
- Benzalkonium Gel, standard of care topical gel, Debridement, benzalkonium irrigation, Saline Irrigation (SOC Irrigation)
- Drug · Other · Procedure
- Lead sponsor
- Georgetown University
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Open Fracture
- Interventions
- Vancomycin (VAN) treatment, Standard Open Fracture Care
- Drug · Other
- Lead sponsor
- Atlantic Health System
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Morristown, New Jersey
- Conditions
- Bone Marrow Edema, Knee Pain Chronic, Knee Osteoarthritis, Osteoarthritis, Knee, Osteoarthritis
- Interventions
- Subchondroplasty with Arthroscopy, Arthroscopy Alone
- Procedure
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 30 Years to 75 Years
- Enrollment
- 131 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 12
- States / cities
- Encinitas, California • Loma Linda, California • Stanford, California + 9 more
- Conditions
- Tibial Fractures, Nonunion of Fracture, Delayed Union of Fracture
- Interventions
- Intramedullary Bone Graft
- Procedure
- Lead sponsor
- University of Louisville
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- Louisville, Kentucky
- Conditions
- Chronic Sinusitis
- Interventions
- Steroid-releasing sinus implant, Post-op standard of care
- Device · Other
- Lead sponsor
- ENT and Allergy Associates, LLP
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 4
- States / cities
- Lake Success, New York • New York, New York • Port Jefferson, New York + 1 more
- Conditions
- Chronic Wound
- Interventions
- Next Science Group, Control Group, Antibacterial Control Group
- Device
- Lead sponsor
- Next Science TM
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Abscess
- Interventions
- IRRISEPT, Usual Care
- Device · Procedure
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Prosthetic Joint Infection, Debridement With Prosthesis Retention, Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee, Suture
- Interventions
- VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament
- Device
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 142 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Osseointegration Infection
- Interventions
- intraosseous antibiotic delivery
- Procedure
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2031
- U.S. locations
- 5
- States / cities
- Aurora, Colorado • New York, New York • Charlotte, North Carolina + 2 more
- Conditions
- Wounds and Injuries
- Interventions
- V.A.C.Ulta with Prontosan instillation, V.A.C.Ulta without instillation
- Device
- Lead sponsor
- KCI USA, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 181 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 7
- States / cities
- Washington D.C., District of Columbia • Miami, Florida • Chicago, Illinois + 4 more
- Conditions
- Gustilo-Anderson Type III Open Tibia Fracture
- Interventions
- Irrisept (Irrigation Solution), Saline
- Drug
- Lead sponsor
- Brett D. Crist
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Foot Ulcer, Diabetic
- Interventions
- DERMASEAL, Plasma Film, Standard of Care
- Combination Product · Biological · Other
- Lead sponsor
- Vitruvian Medical Devices, Inc.
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 26 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 4
- States / cities
- Fresno, California • South Miami, Florida • Boardman, Ohio + 1 more
- Conditions
- Trauma, Infection, Bone Fracture
- Interventions
- Imaging using 5-Aminolevulinic Acid (5-ALA) during surgery
- Procedure
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 18 Years to 100 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Lebanon, New Hampshire
- Conditions
- Surgical Wound Dehiscence
- Interventions
- VERSAJET, Scalpel or blade
- Device · Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Surgical Wound Infection
- Interventions
- Next Science, Standard of Care
- Device · Other
- Lead sponsor
- Next Science TM
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 2
- States / cities
- Birmingham, Alabama • Columbus, Georgia