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Showing 1–24 of 2,131 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: diet and physical activity Clear all
Completed Not applicable Interventional

Effects of a Whole-food, Plant-based Nutrition Program on BP and Potassium in Subjects With CKD

NCT06343129
View directory record Official record
Conditions
Chronic Kidney Diseases
Interventions
Dietary education program
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Molecular Mechanisms Underlying Anabolic Resistance to Protein Intake During Muscle Disuse

NCT06228742
View directory record Official record
Conditions
Atrophy, Disuse, Muscle Atrophy, Muscular Disorders, Atrophic, Disuse Atrophy, Disuse Atrophy Muscle of Thigh
Interventions
Unilateral leg immobilization, Contralateral active leg
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2024 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Phase 4 Interventional Results available

Comparing a Virtual vs. Face to Face Weight Management Program Using Phentermine for Patients With Overweight or Obesity

NCT04614545
View directory record Official record
Conditions
Obesity
Interventions
Phentermine 37.5 Mg, Dietary program, Exercise program
Drug · Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 6, 2022 · Synced Sep 18, 2026, 6:02 PM EDT
Not listed Not applicable Interventional

Perioperative Optimization With Enhanced Recovery

NCT04504266
View directory record Official record
Conditions
Complication of Surgical Procedure
Interventions
POWER
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 14, 2024 · Synced Sep 18, 2026, 6:02 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Assessing Obesity Related Risk Factors in Adult Population: A Genetic and Behavioral Study

NCT07341841
View directory record Official record
Conditions
Obesity Prevention
Interventions
Diet and exercise, Lifestyle Intervention, Exercise
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 18, 2026, 6:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Hormone Dynamics and Bone Mineral Density in Anorexia Nervosa v. Hypothalamic Amenorrhea

NCT00556036
View directory record Official record
Conditions
Anorexia Nervosa, Hypothalamic Amenorrhea, Obesity
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2020 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Not applicable Interventional Results available

My Recordable On-Demand Audio Discharge Instructions

NCT02901314
View directory record Official record
Conditions
Heart Failure, Congestive
Interventions
on-demand audio messages of heart failure education themes
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
2,487 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
4
States / cities
Cleveland, Ohio • Mayfield Heights, Ohio • Medina, Ohio
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Community-Based Nutrition-Lifestyle Therapy for Pregnant Latina Women With Diabetes

NCT06218147
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Diabetes Mel Gestational - in Pregnancy
Interventions
Nutrition-behavior lifestyle program
Behavioral
Lead sponsor
Sansum Diabetes Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Not applicable Interventional

The PREVENTION Trial: Precision Recommendations to Optimize Neurocognition

NCT04082611
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment
Interventions
Data-Driven Clinical Recommendations, Coached Data-Driven Clinical Recommendations
Behavioral
Lead sponsor
Saint John's Cancer Institute
Other
Eligibility
50 Years to 80 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Family Diabetes Prevention Program Pilot Study

NCT05358444
View directory record Official record
Conditions
PreDiabetes, Overweight and Obesity, Type 2 Diabetes, Overweight, Childhood, Obesity, Childhood, Lifestyle, Healthy
Interventions
National Diabetes Prevention Program Lifestyle Intervention (DPP), Family Diabetes Prevention Program (Family DPP)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
5 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

The Multimedia HIV/STI Prevention for Drug-Involved Female Offenders

NCT01784809
View directory record Official record
Conditions
HIV, Sexually Transmitted Infections
Interventions
Multimedia WORTH, Traditional WORTH, Wellness Promotion
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2014 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Phase 3 Interventional Results available

Improving Reproductive Fitness Through Pretreatment With Lifestyle Modification in Obese Women With Unexplained Infertility

NCT02432209
View directory record Official record
Conditions
Infertility, Female
Interventions
Caloric Restriction, Orlistat, Moderate physical activity
Other · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
379 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
10
States / cities
San Francisco, California • Augusta, Georgia • Southfield, Michigan + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Not applicable Interventional

Pilot and Feasibility Trial of a Telehealth Dietary Intervention for MS

NCT03372187
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
DIET-MS
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 22, 2020 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Phase 2 Interventional

Survival TRaining for ENhancing Total Health (STRENGTH)

NCT00068458
View directory record Official record
Conditions
Breast Cancer, Depression, Weight Changes
Interventions
Calcium-Rich Diet, Arm 2: Exercise + Calcium-Rich Diet, Exercise + Fruit & Vegetable, Low Fat + Calcium Diet
Dietary Supplement · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
4
States / cities
Durham, North Carolina • Goldsboro, North Carolina • Winston-Salem, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 18, 2017 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Parent Involvement in Adolescent Obesity Treatment

NCT03851796
View directory record Official record
Conditions
Pediatric Obesity
Interventions
TEENS+Parents as Coaches, TEENS+Parent Weight Loss
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
12 Years to 16 Years
Enrollment
418 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Henrico, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Calorie Restricted, Very Low Fat Plant-based Diet and Multi-component Exercise Program on Metabolic Health

NCT02706288
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Weight loss with very low fat plant-based diet and regular exercise
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Not applicable Interventional Results available

Project Impact: An Innovative Approach to Weight Loss Maintenance

NCT02363010
View directory record Official record
Conditions
Obesity, Weight Loss, Overweight
Interventions
Gold Standard Behavior Therapy for Weight Loss, Behavior Therapy for Weight Loss with Physical Activity Emphasis, Acceptance-based Behavior Therapy for Weight Loss with PA emphasis
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 70 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 2, 2023 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Phase 2 Interventional Results available

Reduced Carbohydrate Versus Fat in Obese Subjects

NCT00846040
View directory record Official record
Conditions
Obesity
Interventions
Reduced fat diet, Reduced carbohydrate diet, Drug: f-18 fallypride, fMRI, PET
Other · Drug · Device
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 45 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Not applicable Interventional

Automated Guidance Tool for Medical Encounters Addressing Therapeutic Lifestyle Changes (AuGMEnT).

NCT00790491
View directory record Official record
Conditions
Heart Disease, Diabetes
Interventions
guidance tool for providers for lifestyle changes
Behavioral
Lead sponsor
Griffin Hospital
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Waterbury, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 6, 2013 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Phase 3 Interventional

Bioequipotency Study of Idrabiotaparinux and Idraparinux in Patients With Deep Venous Thrombosis of the Lower Limbs

NCT00311090
View directory record Official record
Conditions
Deep Venous Thrombosis
Interventions
Idrabiotaparinux sodium, Idraparinux sodium, Avidin, Placebo (for Avidin)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
757 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 20, 2016 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Not applicable Interventional

Multi-Channel Automated Diet and Physical Activity Intervention for Pre-Diabetics

NCT01479062
View directory record Official record
Conditions
Pre-diabetes, Diabetes, Obesity
Interventions
Alive-PD, Usual Care
Behavioral
Lead sponsor
Berkeley Analytics, Inc.
Industry
Eligibility
40 Years to 79 Years
Enrollment
339 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Not applicable Interventional

Diabetes Prevention for Mexican Americans

NCT03208010
View directory record Official record
Conditions
Prediabetic State, Overweight and Obesity
Interventions
Diabetes Prevention Intervention, Enhanced Usual Care
Behavioral · Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
25 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Rio Grande City, Texas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Sep 18, 2026, 6:02 PM EDT
Recruiting Not applicable Interventional

Weight Management Intervention in College: A Pilot

NCT06994923
View directory record Official record
Conditions
Obesity and Overweight
Interventions
BWLI-College, Control
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 29 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Sep 18, 2026, 6:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

High-fat Meal Challenge in Pediatrics

NCT05230433
View directory record Official record
Conditions
Pediatric Obesity, Insulin Resistance
Interventions
High-fat Challenge
Dietary Supplement
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
8 Years to 17 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 18, 2026, 6:02 PM EDT