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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: dry needling Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Dry Needling the Calf Muscles on Biomechanics and Muscle Function in Individuals With Restricted Dorsiflexion

NCT07474948
View directory record Official record
Conditions
Ankle Stiffness
Interventions
Dry needling
Procedure
Lead sponsor
University of Dayton
Other
Eligibility
18 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 22, 2026, 2:05 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Two Different Dry-Needling Techniques for Low Back Pain

NCT03970486
View directory record Official record
Conditions
Low Back Pain
Interventions
Dry needling
Procedure
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dry Needling and Shoulder Muscle Blood Flow, Motions, and Pain Sensitivity

NCT05467098
View directory record Official record
Conditions
Dry Needling, Shoulder Pain
Interventions
Dry Needling
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional

A Mediation Analysis Investigating Dry Needling Treatment Mechanisms in a Chronic Low Back Pain Population

NCT06940492
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP)
Interventions
Dry needling
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 22, 2026, 2:05 AM EDT
Recruiting Not applicable Interventional

Manual Therapy, Exercise and US Vs. Manual Therapy, Exercise and US for Medial Epicondylalgia

NCT04609735
View directory record Official record
Conditions
Epicondylalgia
Interventions
Electric Dry Needling, Manual Therapy, Exercise and Ultrasound, Manual Therapy, Exercise and Ultrasound
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years to 60 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated May 17, 2025 · Synced Sep 22, 2026, 2:05 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Peri-neural Electrical Dry Needling Migraine Treatment Study

NCT04252391
View directory record Official record
Conditions
Migraine Headache
Interventions
Perineural electrical dry needling, Standard Care
Procedure
Lead sponsor
Wheaton Franciscan Healthcare
Other
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 8, 2022 · Synced Sep 22, 2026, 2:05 AM EDT
Not listed Not applicable Interventional

Dry Needling Effects on Cortical Excitability

NCT05111691
View directory record Official record
Conditions
Low Back Pain
Interventions
Dry needling
Procedure
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 5, 2022 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Early Phase 1 Interventional

Feasibility of Near-infrared Spectroscopy to Measure Cortical Pain Pathway (Brain) Activation During Dry Needling

NCT04170803
View directory record Official record
Conditions
Shoulder Pain, Chronic Pain, Musculoskeletal Injury
Interventions
Dry Needling, Sham Dry Needling
Device · Other
Lead sponsor
Army-Baylor University Doctoral Program in Physical Therapy
Other
Eligibility
18 Years to 50 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Results available

DDN in Stroke--COBRE

NCT05196737
View directory record Official record
Conditions
Stroke, Spasticity, Muscle, CVA
Interventions
Dry Needling
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Deep Trigger Point Dry Needling on Strength Measurements of the Gluteus Medius Musculature

NCT03580200
View directory record Official record
Conditions
Trigger Point, Muscle Weakness
Interventions
Trigger Point Dry Needling
Other
Lead sponsor
Emily Slaven, PT, PhD
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dry Needling in Subjects With Delayed Onset Muscle Soreness

NCT03876080
View directory record Official record
Conditions
Delayed Onset Muscle Soreness
Interventions
Dry needling, Sham needling
Other
Lead sponsor
Bradley University
Other
Eligibility
18 Years to 35 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dry Needling vs Dry Needling With ES in Patients With Neck/Shoulder Pain

NCT03638388
View directory record Official record
Conditions
Myofascial Pain, Neck Pain, Shoulder Pain
Interventions
Dry needling (DN), Dry needling with intramuscular electrical stimulation (DNES)
Procedure
Lead sponsor
Kindyle Brennan
Other
Eligibility
18 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Belton, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2019 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Spinal Manipulation and Dry Needling Versus Conventional Physical Therapy in Patients With Sacroiliac Dysfunction

NCT02373644
View directory record Official record
Conditions
Sacroiliac Joint Dysfunction
Interventions
HVLA Thrust Manipulation and DN, Conventional Physical Therapy
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Hamstring Tightness

NCT02516137
View directory record Official record
Conditions
Hamstring Tightness
Interventions
Dry needling, Sham needling, Blunt needle placement, Standard hamstring stretching exercise
Procedure · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 4, 2017 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Dry Needling for Patients With Neck Pain

NCT02731014
View directory record Official record
Conditions
Neck Pain
Interventions
Dry Needling, Sham Dry Needling, Manual Therapy, Exercise
Other
Lead sponsor
Franklin Pierce University
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Indianapolis, Indiana • Concord, New Hampshire
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Immediate Decrease of Muscle Biomechanical Stiffness Following Dry Needling in Asymptomatic Participants

NCT04864704
View directory record Official record
Conditions
Healthy
Interventions
dry needling
Other
Lead sponsor
Bradley University
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Sep 22, 2026, 2:05 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques

NCT07112404
View directory record Official record
Conditions
Pain, Back Pain, Lower Back Pain, Quality of Life
Interventions
Dry Needling, Dry needling with high-rate PENS, Dry needling with low-rate PENS
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Dry Needling and Stretching vs. Stretching Alone on Hamstring Flexibility in Patients With Knee Pain

NCT02498704
View directory record Official record
Conditions
Mobility Limitation
Interventions
Dry Needling, Sham Needling
Procedure · Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Feb 22, 2016 · Synced Sep 22, 2026, 2:05 AM EDT
Not yet recruiting Not applicable Interventional

Conservative Care for Pelvic Pain (C2P2) in Women Service Members

NCT06697548
View directory record Official record
Conditions
Chronic Pelvic Pain
Interventions
Pain Neuroscience Education, Lumbopelvic and Hip Therapeutic Exercise, Extrapelvic Manual Therapy, Extrapelvic Dry Needling, Deep Paced Diaphragmatic Breathing Training, Chronic Pelvic Pain Education, Intravaginal and intrarectal pelvic floor physical therapy
Other
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
San Antonio, Texas • Waco, Texas
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Dry Needling for Sub Acromial Pain Syndrome

NCT03442894
View directory record Official record
Conditions
Subacromial Impingement Syndrome
Interventions
Standard Physical Therapy Treatment, Dry Needling, Sham Dry Needling
Procedure
Lead sponsor
59th Medical Wing
Federal
Eligibility
18 Years to 65 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Sep 22, 2026, 2:05 AM EDT
Not listed Not applicable Interventional

Superficial Dry Needling for Cervicogenic Headache

NCT05444296
View directory record Official record
Conditions
Headache
Interventions
Superficial Dry Needling, Non-thrust Mobilizations only
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 10, 2022 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Dry Needling on Muscle Stiffness, Gait, Motion, and Strength in Healthy Individuals With Trigger Points

NCT03689283
View directory record Official record
Conditions
Trigger Point Pain, Myofascial
Interventions
Dry Needling, Sham Dry Needlling
Other
Lead sponsor
Regis University
Other
Eligibility
18 Years to 50 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Sep 22, 2026, 2:05 AM EDT
Withdrawn Not applicable Interventional

Effectiveness of Dry Needling and STM on Pain Management for Anterior Cruciate Ligament Reconstruction (ACLR)

NCT03506685
View directory record Official record
Conditions
Pain and Anterior Cruciate Ligament Reconstruction
Interventions
Dry needling and STM
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Sep 22, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trigger Point Dry Needling Practice in Colorado: Practitioner and Patient

NCT04040218
View directory record Official record
Conditions
Dry Needling, Harm
Interventions
Dry Needling
Procedure
Lead sponsor
Regis University
Other
Eligibility
18 Years and older
Enrollment
2,607 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Sep 22, 2026, 2:05 AM EDT