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ClinicalTrials.gov public records Last synced Nov 7, 2026, 12:35 AM EST

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Showing 25–48 of 426 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: electronic cigarette Clear all

Conditions: Tobacco Use, E-Cigarette Use, Cardiovascular Diseases, Pulmonary Disease
Interventions: Cigarettes, E-Cigarettes; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 450 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Tobacco Use
Interventions: e-cigarette, Nicotine patch, Nicotine lozenge; Behavioral · Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Premature Atrial Contractions, Premature Ventricular Contractions
Interventions: Randomized instructions; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years and older
Enrollment: 108 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 2
States / cities: San Francisco, California

Conditions: COPD
Interventions: E-cigarette (EC), Nicotine Replacement Therapy (NRT), Smoking Harm Reduction Counseling Sessions; Other · Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 21 Years to 75 Years
Enrollment: 146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: THC, Cannabis, Cannabis Smoking, Cannabis Use, Unspecified, Cigarette Smoking, Tobacco Use, Nicotine Dependence, Nicotine Withdrawal, Cardiovascular Risk Factor
Interventions: Smoked Cannabis, Vaped Cannabis, Tobacco Cigarette; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years and older
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 2
States / cities: San Francisco, California

Conditions: Message Exposure (Sequence: Regular Then Flavor), Message Exposure (Sequence: Flavor Then Regular), No Message Exposure (Control Condition)
Interventions: Exposure to Anti-Vaping Messages (generic themes then flavor-specific themes), Exposure to Anti-Vaping Messages (flavor-specific themes then generic themes), Exposure to Anti-Vaping Messages (no message exposure); Behavioral
Lead sponsor: University of Georgia; Other
Eligibility: 18 Years to 29 Years
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Athens, Georgia

Conditions: Vaping Behaviors, Message Exposure, Young Adults
Interventions: Intervention, Control; Other
Lead sponsor: University of Hawaii; Other
Eligibility: 18 Years to 24 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Honolulu, Hawaii

Conditions: Nicotine Labeling for E-cigarettes
Interventions: Updated Labeling; Other
Lead sponsor: Yale University; Other
Eligibility: 14 Years and older
Enrollment: 2,500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: E Cigarette Use
Interventions: adapted vaping cessation intervention; Behavioral
Lead sponsor: Veterans Medical Research Foundation; Other
Eligibility: 18 Years to 30 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: San Diego, California

Conditions: Smoking Cessation, Harm Reduction
Interventions: Varenicline, e-cigarette; Drug · Other
Lead sponsor: Rose Research Center, LLC; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Charlotte, North Carolina • Raleigh, North Carolina

Conditions: Vaping, Underage
Interventions: IKE System; Other
Lead sponsor: IKE Tech; Industry
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 4
States / cities: Los Angeles, California • Chicago, Illinois • New York, New York + 1 more

Conditions: Tobacco Use Disorder
Interventions: E-cigarette product; Device
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 21 Years and older
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Electronic Cigarettes
Interventions: JUUL electronic cigarette, IQOS electronic cigarette, Own Brand cigarette; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 21 Years to 55 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Nicotine Dependence, E-Cig Use
Interventions: Nicotine patch, Phone Counseling, Digital Coaching; Drug · Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 24 Years
Enrollment: 508 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Tobacco Use
Interventions: Normal Nicotine Content Vape with all flavor e-liquids, Normal nicotine content vape with tobacco e-liquids, Low nicotine content vape with all flavor e-liquids, Low nicotine content vape with tobacco e-liquids; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 21 Years and older
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Nicotine Dependence, Other Tobacco Product
Interventions: Nicotine, Low Dose Menthol, High Dose Menthol; Drug · Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 20 Years
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: E Cigarette Use, Cessation, Tobacco, Cessation, Nicotine
Interventions: Nicotine Replacement Therapies, Brief Behavioral Counseling; Drug · Behavioral
Lead sponsor: West Virginia University; Other
Eligibility: 21 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: Greenville, North Carolina • Morgantown, West Virginia

Conditions: Vaping, Complication of Anesthesia
Interventions: Not listed
Lead sponsor: Navy Medical Center San Diego; Federal
Eligibility: 12 Years to 80 Years
Enrollment: 300 participants
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: San Diego, California

Conditions: Smoking Cessation
Interventions: Smoking cessation; Behavioral
Lead sponsor: Virtua Health, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Voorhees Township, New Jersey

Conditions: Vaping Teens, Healthy Volunteers
Interventions: Mindfulness-based Stress Reduction (MBSR) Program, functional magnetic resonance imaging (fMRI); Behavioral · Other
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 13 Years to 18 Years
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Smoking, Tobacco Smoking Behavior, Cigarette Smoking
Interventions: Usual brand cigarettes, Lower nicotine content cigarettes, Electronic cigarettes 1, Electronic cigarettes 2; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Smoking Cessation
Interventions: Smoking cessation e-visit, Treatment As Usual; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 672 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Attentional Bias, Smoking Cues, Positive Perceptions About Cigarette Smoking, Social Norms, Smoking Susceptibility
Interventions: E-cigarette ad exposure, non e-cigarette TV commercials; Behavioral · Other
Lead sponsor: Trustees of Dartmouth College; Other
Eligibility: 14 Years to 17 Years
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Smoking, Cigarette, Nicotine Dependence
Interventions: Nicotine (electronic cigarette), Nicotine (nicotine pouch); Other
Lead sponsor: Brown University; Other
Eligibility: 21 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Providence, Rhode Island

Search by objective public record fields.

E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease

Quit or Switch: E-cigarette Study

The MARY-JANE Cannabis and Heart Rhythm Trial

Electronic Cigarettes as a Harm Reduction Strategy Among Patients With COPD

THC Crossover Study

Neuroimaging Approaches to Improve Prediction of Smoking Initiation and Nicotine Escalation in Young Adult ENDS Users

A Text Messaging Trial to Test Vaping Health Messages Optimized to Young Adults' Vaping Status

Survey to Test the Nicotine Concentration and Nicotine Flux Labels for E-cigarettes

Adapting an Intervention for Vaping in Young Veterans

Combination of E-cigarettes and Varenicline for Tobacco Harm Reduction

Human Factors Validation and Usability Testing of the IKE Age-Gating System

Comparative Acceptability of Tobacco and Menthol Flavored E-cigarettes

Assessment of Two New Electronic Cigarettes in Cigarette Smokers

Research and Innovation to Stop E-cigarette/Vaping in Young Adults

Cigarette and E-cigarette Nicotine Content in an Electronic Tobacco Marketplace (ETM)

Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1

Evaluation of Dependence and Nicotine Replacement Therapy-Supported Cessation Efforts Among Regular Electronic Cigarette Use

Perioperative Vaping Complications

Effectiveness of Smoking Cessation Program in a Community Health System

Hippocampal Network Changes Following Mindfulness Training in Tobacco Vaping Adolescents in an Open-label, Pilot Study

Novel Approaches to Reducing Tobacco Related Harm

Enhancing Smoking Cessation Via Telehealth Options in Primary Care

Trial on the Effect of E-cigarette Advertising on Cigarette Perceptions in Adolescents

Using ANDS to Reduce Harm for Low SES Cigarette Smokers