Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 2, 2026, 12:30 AM EDT

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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
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Conditions
Traumatic Brain Injury, Traumatic Brain Injury | Patient, TBI, TBI-Traumatic Brain Injury, TBI (Traumatic Brain Injury)
Interventions
Home-Based Rhythmic Auditory Stimulation
Device
Lead sponsor
Craig Hospital
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Englewood, Colorado
Recruiting Not applicable Interventional

Speech and Arm Combined Exergame

NCT06817941
Conditions
Cerebral Palsy (CP), Dysarthria
Interventions
Speech only, Hand/Arm only, Speech and arm combined
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
8 Years to 17 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Newark, New Jersey
Conditions
Major Depressive Disorder, Bipolar Disorder, Mild Cognitive Impairment
Interventions
Observational assessment using functional near-infrared spectroscopy (fNIRS), a noninvasive, portable brain imaging tool that measures changes in brain blood flow and oxygen levels.
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
200 participants
Timeline
2025 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Major Depressive Disorder (MDD), fNIRS
Interventions
fNIRS measurement
Other
Lead sponsor
Kernel
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Los Angeles, California • Sunnyvale, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Oxygen Toxicity: Mechanisms in Humans

NCT05761756
Conditions
Oxygen Toxicity, Hypercapnia, Seizures
Interventions
Sleep Deprivation, Caffeine, Methylphenidate, Carbon Dioxide
Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 45 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Traumatic Brain Injury
Interventions
Sildenafil Citrate 50Mg Tab, functional Near-infrared Spectroscopy (fNIRS), Carbon Dioxide (CO2) 5%, Neuropsychological Assessments, Gadolinium contrast infusion, Blood sample collection for research purposes, Structural brain Magnetic Resonance Imaging (MRI
Drug · Device · Other + 1 more
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 55 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
TBI
Interventions
Sildenafil citrate, Functional Near Infared Spectroscopy, Hypercapnia Challenge
Drug · Device · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed No phase listed Observational Accepts healthy volunteers

Measure of Cerebrovascular Dysfunction After TBI With fNIRS

NCT01789164
Conditions
Traumatic Brain Injury, Post-concussion Syndrome
Interventions
Not listed
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rockville, Maryland
Conditions
Fragile X Syndrome
Interventions
Speech discrimination
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
24 Months to 4 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Fragile X Syndrome
Interventions
Speech discrimination
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Months to 26 Months
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cue-Centered Treatment (CCT), Trauma-Focused CBT (TF-CBT), Treatment as Usual, NIRScout
Behavioral · Device
Lead sponsor
Stanford University
Other
Eligibility
7 Years to 18 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Sacramento, California • San Francisco, California
Conditions
Pain
Interventions
fNIRS
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Month to 16 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Shoulder Pain, Chronic Pain, Musculoskeletal Injury
Interventions
Dry Needling, Sham Dry Needling
Device · Other
Lead sponsor
Army-Baylor University Doctoral Program in Physical Therapy
Other
Eligibility
18 Years to 50 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Completed No phase listed Observational Accepts healthy volunteers

Investigating Mild Cognitive Impairment in Patients And Controls With TD-fNIRS

NCT05996575
Conditions
Mild Cognitive Impairment
Interventions
fNIRS measurement
Other
Lead sponsor
Kernel
Industry
Eligibility
55 Years to 85 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
6
States / cities
Carlsbad, California • Costa Mesa, California • Escondido, California + 3 more
Conditions
Depression, Major Depressive Disorder
Interventions
fNIRS measurement
Other
Lead sponsor
Kernel
Industry
Eligibility
18 Years to 75 Years
Enrollment
540 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
10
States / cities
Costa Mesa, California • La Jolla, California • Los Angeles, California + 4 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain/Craving Response to Smoking Cues After Oral Nicotine Pouch Use

NCT07698470
Conditions
Nicotine Dependence
Interventions
Oral Nicotine Pouch, Smoking Cue Reactivity Task
Other · Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
21 Years to 55 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Palsy Supranuclear, Supranuclear Palsy, Progressive
Interventions
Repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
40 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Cochlear Implant, Cochlear Implant Users, Cochlear Implant Recipients, Cochlear Implant Listeners
Interventions
AC Group, CA group
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 95 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Intellectual Disability
Interventions
TSA2 Thermosensory Stimulator
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
8 Years to 30 Years
Enrollment
215 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Bethesda, Maryland