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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: hyperbaric oxygen Clear all
Completed No phase listed Observational

Hyperbaric Oxygen and Its Effect on Radiation Induced Long Term Side Effects

NCT02450305
View directory record Official record
Conditions
Cancer of Head and Neck
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Sep 18, 2026, 2:30 AM EDT
Terminated Phase 2 Interventional

Acute Post-Radiation Hyperbaric Oxygen (HBO2) for Breast Cancer Patients Who Have Recently Completed Radiation Therapy

NCT03916068
View directory record Official record
Conditions
Breast Cancer
Interventions
Hyperbaric Oxygen Therapy, Trental Pill, Vitamin E
Procedure · Drug · Dietary Supplement
Lead sponsor
Legacy Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Sep 18, 2026, 2:30 AM EDT
Completed Phase 2 Interventional Results available

Effects of Hyperbaric Oxygen (HBO) on Blood Count Recovery After Autologous Hematopoietic Stem Cell (HSPC) Transplant for Multiple Myeloma

NCT03398200
View directory record Official record
Conditions
Myeloma
Interventions
Hyperbaric Oxygen Therapy, No Hyperbaric Oxygen Therapy
Biological · Other
Lead sponsor
Omar Aljitawi
Other
Eligibility
18 Years to 75 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
3
States / cities
Fairway, Kansas • Lexington, Kentucky • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Sep 18, 2026, 2:30 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of HBO on Glucose in Patients With DM

NCT04261738
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Interventions
Hyperbaric Oxygen
Device
Lead sponsor
Legacy Health System
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 18, 2026, 2:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Pre-dive Ketone Food Products on Latency to CNS Oxygen Toxicity (Aim 2)

NCT05831228
View directory record Official record
Conditions
Oxygen Toxicity
Interventions
Ketogenic food products, Control: Placebo
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
18 Years to 39 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 18, 2026, 2:30 AM EDT
Completed Phase 2 Interventional

Hyperbaric Oxygen Effects on Persistent Post-concussive Symptoms

NCT05173818
View directory record Official record
Conditions
Persistent Post-concussive Syndrome, Concussion Post Syndrome
Interventions
Hyperbaric oxygen at 1.5 ATA, Sham treatment
Drug
Lead sponsor
Essentia Health
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 18, 2026, 2:30 AM EDT
Terminated Phase 3 Interventional

Study to Determine if Hyperbaric Oxygen Therapy is Helpful for Treating Radiation Tissue Injuries

NCT00134628
View directory record Official record
Conditions
Radiation Injuries
Interventions
Hyperbaric Oxygen Therapy, Sham treatment
Procedure
Lead sponsor
National Baromedical Services
Other
Eligibility
Not listed
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2015
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 11, 2016 · Synced Sep 18, 2026, 2:30 AM EDT
Not listed Phase 1 Interventional

Oxygen Toxicity of HBOT in Chronic Brain Injury

NCT00592891
View directory record Official record
Conditions
Adult and Pediatric Chronic Cerebral Disorders
Interventions
Hyperbaric oxygen therapy
Drug
Lead sponsor
Paul G. Harch, M.D.
Other
Eligibility
Not listed
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2016
U.S. locations
1
States / cities
Marrero, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 4, 2015 · Synced Sep 18, 2026, 2:30 AM EDT
Completed Not applicable Interventional

Use of Hyperbaric Oxygen Therapy to Treat COVID-19 Patients With Respiratory Distress

NCT04800120
View directory record Official record
Conditions
Covid19
Interventions
Hyperbaric Oxygen Therapy
Other
Lead sponsor
Steward St. Elizabeth's Medical Center of Boston, Inc.
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Taunton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Sep 18, 2026, 2:30 AM EDT
Not listed Phase 4 Interventional

Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer

NCT00906269
View directory record Official record
Conditions
Impotence, Prostatic Neoplasms
Interventions
Sildenafil therapy plus post-NSRRP HBO2T, Sildenafil therapy plus sham post-NSRRP HBO2T
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
40 Years to 65 Years · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2021
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 19, 2019 · Synced Sep 18, 2026, 2:30 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Hyperbaric Treatment of Traumatic Brain Injury (TBI)

NCT01847755
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Oxygen at 1.5 ATA (atmospheres absolute).
Drug
Lead sponsor
Barry Miskin, MD
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Jupiter, Florida
Source: ClinicalTrials.gov public record
Updated Apr 26, 2021 · Synced Sep 18, 2026, 2:30 AM EDT
Recruiting Phase 2 Interventional

Hyperbaric Oxygen Brain Injury Treatment Trial

NCT02407028
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Hyperbaric oxygen (1.5 ATA, no NBH), Hyperbaric oxygen (2.0 ATA, no NBH), Hyperbaric oxygen (2.5 ATA, no NBH), Hyperbaric oxygen (1.5 ATA + NBH), Hyperbaric oxygen (2.0 ATA + NBH), Hyperbaric oxygen (2.5 ATA + NBH), Normobaric Hyperoxia (NBH), Usual Care
Drug · Other
Lead sponsor
Gaylan Rockswold
Other
Eligibility
16 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2029
U.S. locations
10
States / cities
San Diego, California • West Palm Beach, Florida • Iowa City, Iowa + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 18, 2026, 2:30 AM EDT
Terminated Not applicable Interventional Results available

Hyperbaric Oxygen Therapy as Adjunctive Therapy to Scaling and Root-planing in the Management of Periodontitis in Patients With Type 2 Diabetes

NCT02671136
View directory record Official record
Conditions
Diabetes, Periodontitis
Interventions
Hyperbaric Oxygen therapy, Conventional Wound Therapies
Device · Other
Lead sponsor
Loma Linda University
Other
Eligibility
35 Years to 80 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2019 · Synced Sep 18, 2026, 2:30 AM EDT
Completed Not applicable Interventional

Hyperbaric Oxygen Therapy for Post-Concussion Syndrome

NCT05643482
View directory record Official record
Conditions
Post-Concussion Syndrome
Interventions
Hyperbaric Oxygen Treatment, Placebo gas
Device · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 18, 2026, 2:30 AM EDT
Not listed Phase 2 Interventional

Hyperbaric Hyperoxygenation With Radiotherapy and Temozolomide in Adults With Newly Diagnosed Glioblastoma

NCT00936052
View directory record Official record
Conditions
Glioblastomas, Gliosarcoma
Interventions
Hyperbaric Oxygen Therapy
Other
Lead sponsor
Neurological Surgery, P.C.
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
2
States / cities
Commack, New York • Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2010 · Synced Sep 18, 2026, 2:30 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Normative Datasets for Assessments Planned for Mild Traumatic Brain Injury (NORMAL)

NCT01925963
View directory record Official record
Conditions
Focus: Healthy Adults Without Brain Injury
Interventions
Not listed
Lead sponsor
Lindell Weaver
Other
Eligibility
18 Years to 65 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 26, 2018 · Synced Sep 18, 2026, 2:30 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Hyperbaric Oxygen Therapy on Surgical Wound Healing

NCT01605110
View directory record Official record
Conditions
Edema, Ecchymosis
Interventions
Hyperbaric oxygen treatment, Air sham
Drug
Lead sponsor
Restorix Research Institute, LLLP
Other
Eligibility
40 Years to 85 Years
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Issaquah, Washington
Source: ClinicalTrials.gov public record
Updated Dec 4, 2012 · Synced Sep 18, 2026, 2:30 AM EDT
Withdrawn Early Phase 1 Interventional

Effect of Adjuvant Hyperbaric Oxygen Therapy on Bells Palsy Outcome

NCT03457025
View directory record Official record
Conditions
Bell Palsy
Interventions
Oral Corticosteroids, Oral antivirals, Hyperbaric Oxygen Therapy
Drug · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2020 · Synced Sep 18, 2026, 2:30 AM EDT
Terminated Phase 2Phase 3 Interventional

Hyperbaric Oxygen for Ulcerative Colitis

NCT02144350
View directory record Official record
Conditions
Ulcerative Colitis
Interventions
Hyperbaric oxygen, Sham Hyperbaric Air
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
3
States / cities
Rochester, Minnesota • Lebanon, New Hampshire • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Sep 18, 2026, 2:30 AM EDT
Completed Not applicable Interventional Results available

The Effects of Hyperbaric Oxygen on Rheumatoid Arthritis

NCT02984943
View directory record Official record
Conditions
RheumatoId Arthritis
Interventions
Hyperbaric Oxygen
Device
Lead sponsor
David Grant U.S. Air Force Medical Center
Federal
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Travis Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Sep 18, 2026, 2:30 AM EDT
Completed Not applicable Interventional

Effect of Hyperbaric Therapy on Markers of Oxidative Stress in Children With Autism

NCT00263367
View directory record Official record
Conditions
Autism, Oxidative Stress
Interventions
Hyperbaric Oxygen
Other
Lead sponsor
The International Child Development Resource Center
Other
Eligibility
5 Years to 12 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Melbourne, Florida
Source: ClinicalTrials.gov public record
Updated Jun 21, 2011 · Synced Sep 18, 2026, 2:30 AM EDT
Completed Not applicable Interventional Results available

Hyperbaric Oxygen Therapy for Cognition in Diabetic Elderly at High Dementia Risk

NCT03036254
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
HBOT intervention, Sham intervention
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
65 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
New York, New York • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Sep 18, 2026, 2:30 AM EDT
Terminated Not applicable Interventional Results available

An Evaluation of Hyperbaric Treatments for Children With Cerebral Palsy

NCT00290186
View directory record Official record
Conditions
Cerebral Palsy, Cerebral Palsy, Spastic
Interventions
Hyperbaric Oxygen Treatment, Hyperbaric Air Treatment
Device
Lead sponsor
Dayton Children's Hospital
Other
Eligibility
3 Years to 8 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
2
States / cities
Dayton, Ohio • Wpafb, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 27, 2014 · Synced Sep 18, 2026, 2:30 AM EDT
Withdrawn No phase listed Observational

Saliva, Hyperbaric Oxygen Therapy, & Gland Function: A Prospective Study

NCT01532479
View directory record Official record
Conditions
Osteoradionecrosis of the Jaw, Xerostomia
Interventions
Not listed
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2017 · Synced Sep 18, 2026, 2:30 AM EDT