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ClinicalTrials.gov public records Last synced Sep 1, 2026, 5:37 PM EDT

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Showing 1–14 of 14 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: iFR Clear all
Terminated Not applicable Interventional Results available

A Prospective Study of Fractional Flow Reserve Assessment of Intermediate Coronary Stenoses in Severe Aortic Stenosis

NCT03442400
View directory record Official record
Conditions
Coronary Artery Stenoses, Aortic Stenosis
Interventions
Volcano iFR/FFR Verrata Plus coronary pressure/flow wire
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
20 Years to 110 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 4, 2023 · Synced Sep 1, 2026, 5:37 PM EDT
Completed No phase listed Observational Results available

Physiologic Assessment of Coronary Stenosis Following PCI

NCT03084367
View directory record Official record
Conditions
Coronary Artery Disease, Coronary Stenosis, Angina, Unstable, Angina, Stable
Interventions
iFR pullback
Diagnostic Test
Lead sponsor
Volcano Corporation
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
22
States / cities
Long Beach, California • Lakewood, Colorado • Atlanta, Georgia + 17 more
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Sep 1, 2026, 5:37 PM EDT
Terminated No phase listed Observational

Use of Magnetocardiography in Evaluation of Patients Going for Cardiac Catheterization

NCT04044391
View directory record Official record
Conditions
Acute Coronary Syndrome, Coronary Artery Stenosis, Myocardial Ischemia
Interventions
CardioFlux Magnetocardiograph
Diagnostic Test
Lead sponsor
Genetesis Inc.
Industry
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Detroit, Michigan • Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated May 25, 2020 · Synced Sep 1, 2026, 5:37 PM EDT
Completed Not applicable Interventional

Correlation Study of Imaging Data Acquired During CABG With Data Acquired in the Cath Lab

NCT02138305
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
ComboMap XT Guidewire, 'SPY' NIRF During CABG
Device · Procedure
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Sep 1, 2026, 5:37 PM EDT
Completed No phase listed Observational

Radiographic Imaging Validation and EvALuation for Angio iFR (ReVEAL iFR)

NCT03857503
View directory record Official record
Conditions
Cardiac Ischemia, Coronary Artery Disease, Coronary Stenosis
Interventions
iFR
Diagnostic Test
Lead sponsor
Volcano Corporation
Industry
Eligibility
18 Years and older
Enrollment
441 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
19
States / cities
Long Beach, California • Lakewood, Colorado • New Haven, Connecticut + 15 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Sep 1, 2026, 5:37 PM EDT
Completed No phase listed Observational

ADenosine Vasodilator Independent Stenosis Evaluation II - ADVISE II

NCT01740895
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Not listed
Lead sponsor
Volcano Corporation
Industry
Eligibility
18 Years to 85 Years
Enrollment
818 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
30
States / cities
Chandler, Arizona • Gilbert, Arizona • Lakewood, Colorado + 24 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2014 · Synced Sep 1, 2026, 5:37 PM EDT
Completed No phase listed Observational

Fractional Flow Reserve (FFR) Versus Instant Wave-Free Ratio (iFR)

NCT01559493
View directory record Official record
Conditions
Coronary Artery Disease, Plaque, Atherosclerotic
Interventions
Not listed
Lead sponsor
NHS National Waiting Times Centre Board
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2012 · Synced Sep 1, 2026, 5:37 PM EDT
Enrolling by invitation No phase listed Observational

Fractional Flow Reserve and Instantaneous Free-wave Ratio Revascularization Strategies in Women

NCT04599192
View directory record Official record
Conditions
Coronary Disease, Percutaneous Coronary Intervention, Exercise Test, Myocardial Perfusion Imaging, Cardiac Catheterization
Interventions
No study intervention
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 1, 2026, 5:37 PM EDT
Active, not recruiting Not applicable Interventional

Advancing Cath Lab Results With FFRangio Coronary Physiology Assessment

NCT05893498
View directory record Official record
Conditions
Percutaneous Coronary Intervention
Interventions
FFRangio, FFR or NHPR
Device
Lead sponsor
CathWorks Ltd.
Industry
Eligibility
18 Years and older
Enrollment
1,924 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
43
States / cities
La Jolla, California • Long Beach, California • Los Angeles, California + 34 more
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 1, 2026, 5:37 PM EDT
Recruiting Not applicable Interventional

Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease

NCT05701358
View directory record Official record
Conditions
Acute Myocardial Infarction, Coronary Artery Disease
Interventions
Physiology-guided NCL PCI, Angiography-guided NCL PCI
Procedure
Lead sponsor
Population Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
5,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
13
States / cities
Los Angeles, California • San Francisco, California • Wichita, Kansas + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Sep 1, 2026, 5:37 PM EDT
Terminated Not applicable Interventional Results available

Novel Adenosine-independent Index of Coronary Artery Stenosis Severity Resting Flow Reserve

NCT03461705
View directory record Official record
Conditions
Coronary; Ischemic
Interventions
Volcano Verrata Pressure Wire, St. Jude Medical (SJM) Aeris Pressure Wire System
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Sep 1, 2026, 5:37 PM EDT
Not listed Not applicable Interventional

Functional Lesion Assessment of Intermediate Stenosis to Guide Revascularisation

NCT02053038
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
iFR, FFR
Device
Lead sponsor
Imperial College London
Other
Eligibility
18 Years to 90 Years
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
6
States / cities
Long Beach, California • Lakewood, Colorado • Atlanta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Sep 1, 2026, 5:37 PM EDT
Completed No phase listed Observational

Diastolic Hyperemia Free Index for Assessment of Moderate Coronary Stenoses

NCT04019535
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
physiological assessment with Volcano Verrata pressure wire (iFR)
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 90 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced Sep 1, 2026, 5:37 PM EDT
Recruiting Not applicable Interventional

Diabetes-Centered Evaluation of Revascularization Strategy of Functional and Imaging-CombiNEd State-of-the-Art Percutaneous Coronary Intervention or Coronary-Artery Bypass Grafting in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease

NCT05831085
View directory record Official record
Conditions
Coronary Artery Stenosis
Interventions
State-of-the-Art Percutaneous Coronary Intervention, standard CABG
Procedure
Lead sponsor
Duk-Woo Park, MD
Other
Eligibility
20 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 1, 2026, 5:37 PM EDT