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Showing 73–96 of 130 matching trials from the live ClinicalTrials.gov search.
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Intranasal Oxytocin Administration and the Neural Correlates of Social and Non-Social Visual Perception

NCT02238379
Conditions
Social Perception
Interventions
Oxytocin, Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Intranasal Neuropeptide on Emotion Perception in Trait Anxiety

NCT01551303
Conditions
Social Intelligence
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated Not applicable Interventional Results available

Oxytocin Add-on Study for Stable Anxiety Patients

NCT00989937
Conditions
Anxiety Disorders
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
San Diego, California
Conditions
Post-Traumatic Stress Disorder (PTSD)
Interventions
Oxytocin nasal spray, Saline nasal spray, Brief Cognitive-Behavioral Conjoint Therapy
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
San Diego, California
Conditions
Posttraumatic Stress Disorder
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Alcohol Use Disorder, Alcohol Misuse
Interventions
Instranasal Oxytocin
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Los Angeles, California • Baltimore, Maryland • Boston, Massachusetts + 1 more
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effects of Intranasal Oxytocin on Cigarette Smoking

NCT02595749
Conditions
Nicotine Dependence, Tobacco Smoking
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 40 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Sleep Apnea, Sleep Apnea, Obstructive
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Vivek Jain
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Depression, Postpartum, Anxiety
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated Not applicable Interventional Results available

Oxytocin Add on Study for Stable Schizophrenic Patients

NCT00506909
Conditions
Schizophrenia
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
David Feifel
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
San Diego, California
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Triadic Interactions of Families With Autism and Oxytocin

NCT01912378
Conditions
Autism Disorder
Interventions
Oxytocin, Placebo nasal spray
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
7 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Francisco, California
Conditions
Irritable Mood
Interventions
Functional MRI (fMRI), Oxytocin Intranasal Spray 8 International Unit (8IU), Oxytocin intranasal spray 24 International Unit (24IU), Oxytocin intranasal spray 48 International Unit (48IU), Oxytocin intranasal spray 80 International Unit (80IU), Placebo
Procedure · Drug
Lead sponsor
University of Nebraska
Other
Eligibility
14 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Omaha, Nebraska
Completed Phase 2 Interventional Results available

Intranasal Oxytocin in the Treatment of Autism

NCT00490802
Conditions
Autism
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Evdokia Anagnostou
Individual
Eligibility
18 Years to 60 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
New York, New York
Completed Early Phase 1 Interventional Accepts healthy volunteers

Oxytocin and the Social Brain

NCT02393456
Conditions
Social Psychology
Interventions
Intranasal oxytocin, Intranasal placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 30 Years
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Results available

Effect of Oxytocin on Stress in Marijuana Users

NCT01335789
Conditions
Marijuana Dependence
Interventions
Oxytocin, Saline
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Early Phase 1 Interventional Accepts healthy volunteers

Neuropeptides and Social Behavior

NCT01680718
Conditions
Social Psychology
Interventions
Intranasal oxytocin, Intranasal vasopressin, Intranasal placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 50 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Post Traumatic Stress Disorder, Relational Problems
Interventions
Oxytocin nasal spray, Brief Cognitive-Behavioral Conjoint Therapy
Drug · Behavioral
Lead sponsor
San Diego Veterans Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
San Diego, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intranasal Oxytocin and Maternal Neglect

NCT02737436
Conditions
Maternal Behavior
Interventions
Intranasal Oxytocin, Placebo, Functional MRI scanning
Drug · Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
20 Years to 45 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2019
U.S. locations
2
States / cities
Iowa City, Iowa • Houston, Texas
Completed Early Phase 1 Interventional Results available

Oxytocin Effects on Cardiac Electrophysiology

NCT01780337
Conditions
Cardiac Arrhythmia
Interventions
Oxytocin, Saline
Drug · Other
Lead sponsor
William Whang
Other
Eligibility
18 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Conditions
Pain
Interventions
OxyCODONE 5 mg Oral Tablet, Oxytocin nasal spray, Placebo Oxycodone, Placebo oxytocin, OxyCODONE 2.5 mg Oral Tablet
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 45 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Deciphering the Role of Oxytocin in Motivation: an fMRI Study

NCT01722071
Conditions
Focus of Study: Neural Correlates of Oxytocin Administration
Interventions
Placebo, Oxytocin
Drug
Lead sponsor
Tiffany Love
Other
Eligibility
20 Years to 35 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Phase 2 Interventional Results available

Oxytocin and Social Cognitive Skills Groups

NCT02918864
Conditions
Autism Spectrum Disorder
Interventions
Oxytocin, Social Cognitive Skills Training, Facilitated Play Therapy
Drug · Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
8 Years to 11 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Results available

Effect of Oxytocin on Craving and Therapy Response

NCT01827332
Conditions
Marijuana Dependence
Interventions
Oxytocin, Saline
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Early Phase 1 Interventional Accepts healthy volunteers

Methadone Oxytocin Option

NCT01728909
Conditions
Substance Abuse, Opioid Dependence, Methadone Treatment
Interventions
Oxytocin, Saline Nasal Spray
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Francisco, California