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ClinicalTrials.gov public records Last synced Sep 30, 2026, 12:12 AM EDT

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Showing 25–48 of 392 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: low calorie diet Clear all
Terminated Phase 2 Interventional Results available

A Study To Examine The Efficacy And Safety Of Pramlintide+Metreleptin In Obese Subjects

NCT01235741
View directory record Official record
Conditions
Obesity
Interventions
Pramlintide+Metreleptin, Placebo
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 65 Years
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
18
States / cities
Greenbrae, California • La Jolla, California • Denver, Colorado + 15 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2015 · Synced Sep 30, 2026, 12:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diet, Exercise, Metabolism, and Obesity in Older Women

NCT00664729
View directory record Official record
Conditions
Abdominal Obesity, Metabolic Syndrome
Interventions
Caloric Restriction, Caloric Restriction + Low-Intensity aerobic exercise, Caloric Restriction plus High-intensity aerobic exercise
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
50 Years to 70 Years · Female only
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2008
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Sep 30, 2026, 12:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protective Effect of Exercise on Acute High-fat Overfeeding

NCT07633704
View directory record Official record
Conditions
Insulin Sensitivity/Resistance
Interventions
High Fat Overfeeding, High Fat Overfeeding + Exercise
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
20 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 30, 2026, 12:12 AM EDT
Completed Not applicable Interventional

A Dietary Source of Potassium Citrate to Resolve Hypocitraturia and Aciduria in Patients With Kidney Stones

NCT03984409
View directory record Official record
Conditions
Kidney Calculi
Interventions
Kroger low calorie orange juice beverage
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Sep 30, 2026, 12:12 AM EDT
Completed Phase 4 Interventional Results available

Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects

NCT05548647
View directory record Official record
Conditions
Obesity
Interventions
Behavioral Treatment, Placebo, Semaglutide 2.4 MG/0.75 ML Subcutaneous Solution [WEGOVY]
Behavioral · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 30, 2026, 12:12 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

CALERIE (Washington University): Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy

NCT00099138
View directory record Official record
Conditions
Aging
Interventions
Caloric Restriction (CR), Exercise
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
50 Years to 60 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2006
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 11, 2009 · Synced Sep 30, 2026, 12:12 AM EDT
Not listed Not applicable Interventional

Dietary Sodium (DS) Intervention to Reduce Volume Overload and Tissue Sodium in Magnetic Resonance Imaging (MRI) for Hemodialysis (HD) Patients

NCT03189758
View directory record Official record
Conditions
Kidney Failure, Chronic, Dietary Modification
Interventions
Observational Control Diet, Controlled Dietary Sodium Restriction
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 3, 2020 · Synced Sep 30, 2026, 12:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Time Restricted Eating for the Treatment of PCOS

NCT05629858
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Obesity, Overweight
Interventions
6-h Time restricted eating (TRE), Calorie restriction (CR), Control
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Sep 30, 2026, 12:12 AM EDT
Withdrawn Not applicable Interventional

Cross-over Pilot Study of Blood Cholesterol Response to Dietary Saturated Fat in Patients With Autosomal Dominant Hypercholesterolemia

NCT03756779
View directory record Official record
Conditions
Familial Hypercholesterolemia
Interventions
Dietary intervention
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Sep 30, 2026, 12:12 AM EDT
Recruiting Not applicable Interventional

Support Through Remote Observation and Nutrition Guidance Program for Individuals With Gastroesophageal Cancer

NCT06497569
View directory record Official record
Conditions
GastroEsophageal Cancer
Interventions
Dietitian Consultation, Survey, Fitbit Data Collection, Referral to Dietitian, Social Determinants of Health Survey (SDOH)
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Tampa, Florida • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 30, 2026, 12:12 AM EDT
Active, not recruiting Phase 2 Interventional

A Study of the Body's Response to Exercise and a Plant-Based Diet in Overweight Postmenopausal Women With Breast Cancer

NCT04298086
View directory record Official record
Conditions
Breast Cancer, Primary Hormone Receptor Positive Breast Cancer
Interventions
Exercise Treatment, Plant-Based Diet, Physical activity, Nutrition counseling, Replication Exercise Test
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 30, 2026, 12:12 AM EDT
Terminated Not applicable Interventional

Effects of a Three-Month Low Calorie Diet Weight Loss Intervention on Knee Replacement Outcomes

NCT04015011
View directory record Official record
Conditions
Obesity
Interventions
LCD Intervention
Combination Product
Lead sponsor
NYU Langone Health
Other
Eligibility
50 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2022 · Synced Sep 30, 2026, 12:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain, Obesity, Dopamine and You Study

NCT01094756
View directory record Official record
Conditions
Obesity
Interventions
meal replacements, psychotherapy, dietary education
Dietary Supplement
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 40 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 2, 2016 · Synced Sep 30, 2026, 12:12 AM EDT
Withdrawn Not applicable Interventional

Effect of a Plant Rich Diet on in People With Type 2 Diabetes and Obesity

NCT02977039
View directory record Official record
Conditions
Type 2 Diabetes Mellitus in Obese
Interventions
NDPR diet, USDA healthy eating diet
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Sep 30, 2026, 12:12 AM EDT
Completed No phase listed Observational

Psychological Effects of Bone Marrow Transplants in Children

NCT00645931
View directory record Official record
Conditions
Psychological
Interventions
protein and calorie controlled diet and self-hypnotic relaxation
Behavioral
Lead sponsor
Corewell Health West
Other
Eligibility
1 Day to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 2, 2023 · Synced Sep 30, 2026, 12:12 AM EDT
Active, not recruiting Not applicable Interventional

Renal Oxygen Consumption, Insulin Sensitivity, and Daily Caloric Restriction in ADPKD

NCT06496542
View directory record Official record
Conditions
Autosomal Dominant Polycystic Kidney
Interventions
Daily caloric restriction, Standard advice control
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Sep 30, 2026, 12:12 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Reversal of Lipid-Induced Insulin Resistance

NCT02193295
View directory record Official record
Conditions
Insulin Resistance, NAFLD
Interventions
Caloric Restriction
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 90 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2034
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Sep 30, 2026, 12:12 AM EDT
Completed Not applicable Interventional

Effects of Diet Interventions on Monocytes in Metabolic Syndrome

NCT03591588
View directory record Official record
Conditions
Metabolic Syndrome, Hypertriglyceridemia
Interventions
diet
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
21 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Sep 30, 2026, 12:12 AM EDT
Completed Not applicable Interventional

Improving Maintenance Following Very Low Calorie Diet: The Sustain Lost Weight (SLW) Intervention

NCT01222988
View directory record Official record
Conditions
Obesity
Interventions
Optifast Products
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 17, 2013 · Synced Sep 30, 2026, 12:12 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Protein and Polycystic Ovary Syndrome (PCOS)

NCT07158723
View directory record Official record
Conditions
Polycystic Ovary Syndrome (PCOS)
Interventions
Higher protein dietary pattern, Calorie restriction
Other
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Sep 30, 2026, 12:12 AM EDT
Completed Not applicable Interventional

Exercise and Nutrition on Obese Microbiome

NCT04138303
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Exercise Protocol, Calorie-Restrictive Low Carbohydrate Diet (CR-LC), Ancestral Diet (AD)
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 7, 2020 · Synced Sep 30, 2026, 12:12 AM EDT
Completed Not applicable Interventional

KU Alternate Meal Energy Level Study

NCT03696966
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Portion-Controlled Meals, Low-Calorie Diet, Intermittent Very-Low Calorie Diet
Dietary Supplement · Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2019 · Synced Sep 30, 2026, 12:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CALERIE (PBRC, Baton Rouge) - Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy

NCT00099151
View directory record Official record
Conditions
Aging, Cardiovascular Disease, Diabetes Mellitus
Interventions
Caloric Restriction (CR), Exercise
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
25 Years to 50 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2006
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 11, 2009 · Synced Sep 30, 2026, 12:12 AM EDT
Completed Not applicable Interventional

Diabetes Dietary Study- Low Carbohydrate and Low-Fat Diets in Type 2 Diabetes

NCT00795691
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
low-carbohydrate diet, low-fat diet
Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 12, 2019 · Synced Sep 30, 2026, 12:12 AM EDT