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ClinicalTrials.gov public records Last synced Nov 14, 2026, 8:49 PM EST

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Showing 1–24 of 61 matching trials from the live ClinicalTrials.gov search.
Conditions
Chronic Pain, Osteoarthritis
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Aphasia
Interventions
rTMS, tDCS, Sham rTMS, Sham tDCS
Device
Lead sponsor
Dr. Alexander Thiel
Individual
Eligibility
50 Years to 85 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
White Plains, New York
Active, not recruiting Not applicable Interventional

Noninvasive Vagal Nerve Stimulation

NCT06816004
Conditions
Multiple Sclerosis
Interventions
Remotely Supervised Transcranial Direct Current Stimulation (RS - tDCS), Remotely Supervised Transcutaneous Auricular Vagus Nerve Stimulation (RS - taVNS), Remotely Supervised Transcutaneous Cervical Vagus Nerve Stimulation (RS - tcVNS)
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
25 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Traumatic Brain Injury
Interventions
rTMS, HD-tDCS, Attention Process Training
Device · Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 59 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
5
States / cities
Minneapolis, Minnesota • Albuquerque, New Mexico
Completed Not applicable Interventional Accepts healthy volunteers

Effects of rTMS and tDCS on Motor Function in Stroke

NCT01574989
Conditions
Stroke, Motor Function
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Fibromyalgia
Interventions
Active tDCS, Active Exercise, Sham tDCS, Sham Exercise
Device · Procedure
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Cambridge, Massachusetts
Conditions
Parkinson's Disease
Interventions
low-intensity transcranial electrical stimulation, transcranial ultrasound
Procedure
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
40 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Depressive Disorder, Generalized Epilepsy
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
10 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Active, not recruiting No phase listed Interventional Results available

Effects of tDCS and tUS on Pain Perception in OA of the Knee

NCT02723929
Conditions
Chronic Pain, Osteoarthritis
Interventions
active low-intensity transcranial electrical stimulation/active transcranial ultrasound, Sham low-intensity transcranial electrical stimulation/sham transcranial ultrasound
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Conditions
Major Depressive Disorder, MDD, Depression, Major Depressive Episode
Interventions
transcranial direct current stimulation (tDCS)
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Improving Working Memory in Older Adults

NCT04362696
Conditions
Memory Disorders in Old Age
Interventions
High definition transcranial electrical current stimulation
Device
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 80 Years
Enrollment
964 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Chronic Pain, Post Traumatic Stress Disorder (PTSD), Depression
Interventions
tDCS
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 89 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Major Depressive Disorder
Interventions
Intermittent Theta Burst Stimulation (iTBS), Transcranial Alternating Current Stimulation (tACS), Psychotherapy, Sham (Placebo) Transcranial Alternating Current Stimulation (tACS)
Device · Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Stroke, Rehabilitation, Hand
Interventions
transcranial direct current stimulation and electrical stimulator
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Anxiety, PTSD, ADHD, Depression Disorders, Post-traumatic Stress, Substance Use, Executive Function, Sleep Disturbance
Interventions
AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation, Audiovisual Entrainment, Vibroacoustic Stimulation, Breathwork-Based Auditory Driving Entropy Module (BADEM), Transcranial Electrical Stimulation
Behavioral · Device
Lead sponsor
Tactical Mind Research Coalition, Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Pain, Burn Injury
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Noninvasive Brain Stimulation to Evaluate Neural Plasticity After Stroke

NCT02465034
Conditions
Cerebrovascular Stroke
Interventions
Transcranial Magnetic Stimulation, Traditional Paired Associative Stimulation, Median Nerve Stimulation, Corticocortical Paired Associative Stimulation, Sham Paired Associative Stimulation
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 85 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
2
States / cities
Atlanta, Georgia
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of CES on Parasympathetic Tone

NCT02163967
Conditions
Autonomic Nervous System Imbalance
Interventions
Cranial Electrical Stimulation Fisher-Wallace Stimulator (Model FW100)
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
New York, New York
Conditions
Endometriosis
Interventions
NettleEndo, Sham NettleEndo Device
Device
Lead sponsor
Samphire Group, Inc.
Industry
Eligibility
22 Years to 45 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Enhancement Through Model-based and Individualized Neurostimulation

NCT06235970
Conditions
Transcranial Electrical Stimulation (tES)
Interventions
Transcranial electrical stimulation (tES) including SHAM
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 45 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Chronic Pain, Spinal Cord Injury
Interventions
Transcranial Direct Current Stimulation (tDCS)
Procedure
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Performance Enhancement
Interventions
Transcranial direct current stimulation
Device
Lead sponsor
United States Army Aeromedical Research Laboratory
Federal
Eligibility
18 Years to 40 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Fort Rucker, Alabama
Conditions
Spinal Cord Injury, Chronic Pain, Neuropathic Pain
Interventions
Transcranial direct current stimulation (tDCS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation

NCT06094192
Conditions
Alzheimer Disease
Interventions
High definition transcranial electrical current stimulation
Device
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
50 Years to 100 Years
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts