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Showing 1–24 of 109 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: mifepristone Clear all
Completed Phase 1 Interventional

Mifepristone and Eribulin in Patients With Metastatic Triple Negative Breast Cancer or Other Specified Solid Tumors

NCT02014337
View directory record Official record
Conditions
Breast Cancer, Ovarian Epithelial Cancer Recurrent, Sarcoma, Non-small Cell Lung Cancer, Carcinoma, Transitional Cell, Prostate Cancer, Prostatic Neoplasms
Interventions
Mifepristone and Eribulin in combination
Drug
Lead sponsor
Corcept Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
11
States / cities
Tucson, Arizona • Tampa, Florida • Atlanta, Georgia + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Phase 1Phase 2 Interventional

Anti-HIV Activity and Safety of 3 Different Doses of Mifepristone in HIV Infected People

NCT00099645
View directory record Official record
Conditions
HIV Infections
Interventions
Mifepristone
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2005
U.S. locations
10
States / cities
Torrance, California • Washington D.C., District of Columbia • Minneapolis, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2021 · Synced Sep 1, 2026, 7:48 PM EDT
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Blocking Mifepristone Action With Progesterone

NCT03774745
View directory record Official record
Conditions
Pregnancy, Unwanted
Interventions
Mifepristone 200 MG, micronized Progesterone, Placebo oral capsule
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Phase 3 Interventional Results available

Mifepristone for Labor Induction

NCT05097326
View directory record Official record
Conditions
Induced Vaginal Delivery
Interventions
Mifepristone, Misoprostol
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Phase 2 Interventional Results available

Evaluation of Cortisol Resistance in Young Sedentary and Endurance-Trained Men

NCT01294319
View directory record Official record
Conditions
Cortisol Resistance, Negative Feedback, ACTH, Mineralcorticoid, Glucocorticoid
Interventions
Mifepristone, Placebo, Spironolactone, Combined, Dexamethasone
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 80 Years · Male only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2024 · Synced Sep 1, 2026, 7:48 PM EDT
Terminated Phase 2 Interventional

Mifepristone as Adjunctive Therapy in Alzheimer's Disease

NCT00105105
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Mifepristone
Drug
Lead sponsor
Corcept Therapeutics
Industry
Eligibility
Not listed
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
21
States / cities
Mesa, Arizona • Peoria, Arizona • Fountain Valley, California + 17 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2009 · Synced Sep 1, 2026, 7:48 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Treatment of Schizoaffective Disorder Using Mifepristone

NCT00725270
View directory record Official record
Conditions
Psychotic Disorders, Depressive Disorder, Major, Depressive Disorder
Interventions
Mifepristone, Placebo Oral Tablet
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2009
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2017 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Feasibility of Simplified Telephone Follow-up After Medical Abortion

NCT00619658
View directory record Official record
Conditions
Induced Abortion
Interventions
telephone follow-up
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 27, 2016 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Phase 3 Interventional Results available

Comparative Effectiveness of Pregnancy Failure Management Regimens

NCT02012491
View directory record Official record
Conditions
Spontaneous Abortion
Interventions
Misoprostol, Mifepristone
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
3
States / cities
Sacramento, California • The Bronx, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Enzalutamide and Mifepristone in Treating Patients With Metastatic Hormone Resistant Prostate Cancer

NCT02012296
View directory record Official record
Conditions
Hormone-resistant Prostate Cancer, Recurrent Prostate Cancer, Stage IV Prostate Cancer
Interventions
enzalutamide, mifepristone, laboratory biomarker analysis, pharmacological study
Drug · Other
Lead sponsor
University of Chicago
Other
Eligibility
Male only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
4
States / cities
Chicago, Illinois • Decatur, Illinois • Evanston, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2022 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Not applicable Interventional Results available

Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks

NCT01615731
View directory record Official record
Conditions
Abortion, Induced
Interventions
Mifepristone, Hygroscopic cervical dilators, Misoprostol, Intra-amniotic digoxin
Drug · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
San Jose, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Antiglucocorticoid Therapy for Cognitive Impairment in Late-life Anxiety Disorders

NCT01333098
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Mifepristone
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 17, 2020 · Synced Sep 1, 2026, 7:48 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Medication Enhanced Rapid Therapy

NCT02099825
View directory record Official record
Conditions
Anxiety Disorders
Interventions
d-cycloserine and mifepristone
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exploring a Patient-centered Approach to Mifepristone Administration in Medical Abortion

NCT01811056
View directory record Official record
Conditions
Termination of Pregnancy
Interventions
Mifepristone
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
18 Years and older · Female only
Enrollment
401 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
3
States / cities
New York, New York • Barre, Burlington, Rutland, Vermont • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 12, 2015 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The Extended Gestational Age Medical Abortion Study

NCT00997347
View directory record Official record
Conditions
Medical Abortion
Interventions
Mifepristone and misoprostol
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
18 Years and older · Female only
Enrollment
1,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
6
States / cities
West Palm Beach, Florida • Chicago, Illinois • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2012 · Synced Sep 1, 2026, 7:48 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Mifepristone Versus Misoprostol for Cervical Preparation Prior to Surgical Abortion Between 11 to 15 Weeks

NCT01636063
View directory record Official record
Conditions
Induced Abortion, Abortion Techniques, Mifepristone, Misoprostol
Interventions
Mifepristone, Misoprostol
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 21, 2017 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Not applicable Interventional Results available

Mifepristone Treatment for Patients With Non-psychotic Major Depressive Disorder Receiving Bilateral ECT

NCT00285818
View directory record Official record
Conditions
Depression
Interventions
Mifepristone, Placebo Oral Capsule
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 15, 2017 · Synced Sep 1, 2026, 7:48 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

MiMi: A Randomized Trial of Mifepristone and Misoprostol for Treatment of Early Pregnancy Failure

NCT00468299
View directory record Official record
Conditions
Early Pregnancy Failure, Miscarriage, Fetal Demise, Anembryonic Pregnancy
Interventions
Misoprostol and placebo, Mifepristone and misoprostol
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2011 · Synced Sep 1, 2026, 7:48 PM EDT
Terminated Not applicable Interventional

The Effect of Mifepristone on the Expression of Cervical Prostaglandin EP3 Receptors

NCT01224509
View directory record Official record
Conditions
Cervical Prostaglandin EP3 Receptors, Pregnancy
Interventions
Mifepristone, Non-treatment
Drug · Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2010 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Phase 3 Interventional Results available

Mifepristone Versus Osmotic Dilator Insertion for Cervical Preparation Prior to Surgical Abortion at 15-18 Weeks

NCT01436279
View directory record Official record
Conditions
Cervical Preparation
Interventions
Mifepristone, osmotic dilators
Drug · Device
Lead sponsor
Boston University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Phase 3 Interventional

A United States Extension Study of Corlux for Recurrent Psychotic Symptoms in Psychotic Major Depression

NCT00208156
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Mifepristone
Drug
Lead sponsor
Corcept Therapeutics
Industry
Eligibility
18 Years to 75 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
13
States / cities
San Diego, California • Atlanta, Georgia • Las Vegas, Nevada + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2012 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Phase 4 Interventional

A Controlled Trial of Mifepristone in Gulf War Veterans With Chronic Multisymptom Illness

NCT00691067
View directory record Official record
Conditions
Chronic Multisymptom Illness in Gulf War Veterans
Interventions
mifepristone, Placebos
Drug
Lead sponsor
Bronx Veterans Medical Research Foundation, Inc
Other
Eligibility
35 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Sep 1, 2026, 7:48 PM EDT
Terminated Early Phase 1 Interventional

Glucocorticoid Antagonist Treatment for Tobacco Use Disorder

NCT03248713
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Mifepristone, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 27, 2019 · Synced Sep 1, 2026, 7:48 PM EDT
Completed Phase 1 Interventional

Carboplatin, Gemcitabine Hydrochloride, and Mifepristone in Treating Patients With Advanced Breast Cancer or Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

NCT02046421
View directory record Official record
Conditions
Male Breast Cancer, Recurrent Breast Cancer, Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer, Recurrent Primary Peritoneal Cavity Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer
Interventions
mifepristone, carboplatin, gemcitabine hydrochloride, laboratory biomarker analysis, pharmacological study
Drug · Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Chicago, Illinois • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Sep 1, 2026, 7:48 PM EDT