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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: mifepristone/misoprostol Clear all
Completed Not applicable Interventional Accepts healthy volunteers

A Randomized Trial of Buccal Compared to Oral Misoprostol Following Mifepristone for Medical Abortion up to 63 Days LMP

NCT00386867
View directory record Official record
Conditions
Abortion, Induced
Interventions
800 mcg misoprostol via oral or buccal administration
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
18 Years and older · Female only
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
8
States / cities
Chicago, Illinois • Boston, Massachusetts • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2007 · Synced Sep 26, 2026, 2:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Medication Abortion Via Pharmacy Dispensing

NCT03320057
View directory record Official record
Conditions
Pregnancy Related, Abortion Early
Interventions
Mifepristone, Training on mifepristone dispensing
Drug · Other
Lead sponsor
Daniel Grossman
Other
Eligibility
15 Years and older · Female only
Enrollment
326 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
6
States / cities
Sacramento, California • San Diego, California • San Francisco, California + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 11, 2021 · Synced Sep 26, 2026, 2:22 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Mifepristone and Two Doses of Misoprostol for Abortion at 11&12 Weeks

NCT05119439
View directory record Official record
Conditions
Medical Abortion
Interventions
Mifepristone + 2 doses of misoprostol 800 mcg
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
11 Years to 55 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
6
States / cities
Hilo, Hawaii • Honolulu, Hawaii • Saint Paul, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Sep 26, 2026, 2:22 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Mifepristone Versus Misoprostol for Cervical Preparation Prior to Surgical Abortion Between 11 to 15 Weeks

NCT01636063
View directory record Official record
Conditions
Induced Abortion, Abortion Techniques, Mifepristone, Misoprostol
Interventions
Mifepristone, Misoprostol
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 21, 2017 · Synced Sep 26, 2026, 2:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Mifepristone at Same Time Multicenter Study

NCT00269568
View directory record Official record
Conditions
Abortion Seekers
Interventions
mifepristone and misoprostol
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
1,128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
4
States / cities
Los Angeles, California • Chicago, Illinois • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Sep 26, 2026, 2:22 AM EDT
Completed Phase 4 Interventional Results available

Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled Trial

NCT05322252
View directory record Official record
Conditions
Abortion, Second Trimester, PPROM, Rupture, Spontaneous, Fetal Demise, Fetal Death, Fetal Demise From Miscarriage, Fetal Death Before 22 Weeks With Retention of Dead Fetus, Pregnancy Loss, Pregnancy Complications
Interventions
Mifepristone, Misoprostol
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 26, 2026, 2:22 AM EDT
Terminated Phase 4 Interventional Results available

Methadone and Medication Abortion

NCT04941443
View directory record Official record
Conditions
Pain, Medical Abortion
Interventions
Methadone Pill, Ibuprofen
Drug
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 22, 2023 · Synced Sep 26, 2026, 2:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The Extended Gestational Age Medical Abortion Study

NCT00997347
View directory record Official record
Conditions
Medical Abortion
Interventions
Mifepristone and misoprostol
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
18 Years and older · Female only
Enrollment
1,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
6
States / cities
West Palm Beach, Florida • Chicago, Illinois • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2012 · Synced Sep 26, 2026, 2:22 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Second Trimester Labor Induction

NCT00592215
View directory record Official record
Conditions
Second Trimester Labor Induction
Interventions
Experimental (mifepristone and misoprostol)
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Sep 26, 2026, 2:22 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Non-surgical Alternatives to Treatment of Failed Medical Abortion

NCT02704481
View directory record Official record
Conditions
Abortion Failure
Interventions
Mifepristone, Misoprostol, Placebo mifepristone, Placebo misoprostol
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
18 Years and older · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
14
States / cities
Concord, California • San Diego, California • Denver, Colorado + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2021 · Synced Sep 26, 2026, 2:22 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

MiMi: A Randomized Trial of Mifepristone and Misoprostol for Treatment of Early Pregnancy Failure

NCT00468299
View directory record Official record
Conditions
Early Pregnancy Failure, Miscarriage, Fetal Demise, Anembryonic Pregnancy
Interventions
Misoprostol and placebo, Mifepristone and misoprostol
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2011 · Synced Sep 26, 2026, 2:22 AM EDT
Completed Not applicable Interventional Results available

Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks

NCT01615731
View directory record Official record
Conditions
Abortion, Induced
Interventions
Mifepristone, Hygroscopic cervical dilators, Misoprostol, Intra-amniotic digoxin
Drug · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
San Jose, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Sep 26, 2026, 2:22 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Period Pills for Menstrual Regulation: A New Reproductive Health Option

NCT07671989
View directory record Official record
Conditions
Menstrual Regulation, Menstrual Health Intervention
Interventions
Mifepristone + Misoprostol
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Oakland, California • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 26, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Feasibility of Simplified Telephone Follow-up After Medical Abortion

NCT00619658
View directory record Official record
Conditions
Induced Abortion
Interventions
telephone follow-up
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 27, 2016 · Synced Sep 26, 2026, 2:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Outpatient Medical Abortion With Mifepristone and Misoprostol Through 77 Days of Gestation

NCT02314754
View directory record Official record
Conditions
Medical Abortion
Interventions
Mifepristone followed by misoprostol 24-48 hours later
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
11 Years to 55 Years · Female only
Enrollment
719 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
4
States / cities
Hartford, Connecticut • Atlanta, Georgia • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Sep 26, 2026, 2:22 AM EDT
Not yet recruiting Phase 4 Interventional

The Misoprostol-Only Regimen Evidence Study

NCT07174856
View directory record Official record
Conditions
Abortion, Medical
Interventions
Misoprostol-only medication abortion regimen, Combined regimen
Drug
Lead sponsor
Ibis Reproductive Health
Other
Eligibility
14 Years and older · Female only
Enrollment
1,900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Sep 26, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Self-Assessment of Medical Abortion Outcome Using Serial Multi-level Pregnancy Tests

NCT02570204
View directory record Official record
Conditions
Medical Abortion
Interventions
Self-assessment
Behavioral
Lead sponsor
Gynuity Health Projects
Other
Eligibility
11 Years to 56 Years · Female only
Enrollment
343 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
3
States / cities
West Palm Beach, Florida • Chevy Chase, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2017 · Synced Sep 26, 2026, 2:22 AM EDT
Completed Phase 3 Interventional Results available

Mifepristone Versus Osmotic Dilator Insertion for Cervical Preparation Prior to Surgical Abortion at 15-18 Weeks

NCT01436279
View directory record Official record
Conditions
Cervical Preparation
Interventions
Mifepristone, osmotic dilators
Drug · Device
Lead sponsor
Boston University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Sep 26, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cervical Preparation Before Dilation and Evacuation

NCT01751087
View directory record Official record
Conditions
Abortion, Induced
Interventions
Mifepristone, misoprostol, Osmotic dilators, placebo
Other · Drug · Device
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
7
States / cities
San Francisco, California • Chicago, Illinois • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Sep 26, 2026, 2:22 AM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Mifepristone and Misoprostol for Undesired Pregnancy of Unknown Location

NCT05839899
View directory record Official record
Conditions
Abortion
Interventions
Mifepristone plus one dose Misoprostol, Mifepristone plus two doses Misoprostol
Drug
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 4, 2023 · Synced Sep 26, 2026, 2:22 AM EDT
Completed Not applicable Interventional Results available

Pre-Operative Effects of Mifepristone on Dilation and Evacuation Services

NCT01862991
View directory record Official record
Conditions
Legally Induced Abortion Without Mention of Complication
Interventions
Hygroscopic cervical dilators, Misoprostol, Intra-amniotic digoxin, Mifepristone
Other · Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
San Jose, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Sep 26, 2026, 2:22 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Assessing Medical Menstrual Regulation in the United States

NCT03972358
View directory record Official record
Conditions
Menstrual Regulation
Interventions
Mifepristone, Misoprostol
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
284 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Skokie, Illinois • Chevy Chase, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 23, 2021 · Synced Sep 26, 2026, 2:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Mail Order Mifepristone Study

NCT03913104
View directory record Official record
Conditions
Abortion Early, Pregnancy Related
Interventions
Mifepristone
Drug
Lead sponsor
Daniel Grossman, MD
Other
Eligibility
15 Years and older · Female only
Enrollment
536 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
11
States / cities
Oakland, California • Denver, Colorado • Wilmington, Delaware + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2024 · Synced Sep 26, 2026, 2:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Mifepristone and Misoprostol for Fetal Demise

NCT00177372
View directory record Official record
Conditions
Anembryonic Pregnancy, Gestation Abnormality, Intrauterine Fetal Demise Term
Interventions
mifepristone/misoprostol
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Sep 26, 2026, 2:22 AM EDT