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Showing 1–24 of 121 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: misoprostol Clear all
Completed Phase 2 Interventional Results available

Efficacy and Safety Study of the Misoprostol Vaginal Priming Insert (MVPI) Prior to Hysteroscopy

NCT00925938
View directory record Official record
Conditions
Cervical Priming
Interventions
misoprostol, placebo
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years to 80 Years · Female only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
2
States / cities
Phoenix, Arizona • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 12, 2014 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cervical Foley Plus Vaginal Misoprostol for Labor Induction

NCT01279343
View directory record Official record
Conditions
Induction of Labor
Interventions
Foley bulb
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
16 Years to 45 Years · Female only
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Misoprostol Dose and Timing Before Surgical Abortion at 13 to 16 Weeks' Gestation: a Randomized Trial

NCT02279914
View directory record Official record
Conditions
Abortion, Induced
Interventions
Misoprostol 400 mcg 3 hours prior to procedure, Misoprostol 600 mcg 90 minutes prior to procedure
Drug
Lead sponsor
Planned Parenthood of Greater New York
Other
Eligibility
18 Years and older · Female only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 25, 2021 · Synced Sep 5, 2026, 7:47 AM EDT
Terminated Phase 4 Interventional Results available

Methadone and Medication Abortion

NCT04941443
View directory record Official record
Conditions
Pain, Medical Abortion
Interventions
Methadone Pill, Ibuprofen
Drug
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 22, 2023 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Phase 2 Interventional Results available

Propranolol Versus Placebo for Induction of Labor in Nulliparous Patients

NCT03348683
View directory record Official record
Conditions
Induction of Labor Affected Fetus / Newborn
Interventions
Propranolol, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Sep 5, 2026, 7:47 AM EDT
Withdrawn Phase 4 Interventional

Misoprostol in Office Hysteroscopy and Endometrial Biopsy

NCT03547778
View directory record Official record
Conditions
Office Hysteroscopy and Endometrial Biopsy
Interventions
Misoprostol 50 mcg pesssary, Placebos
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 70 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Sep 5, 2026, 7:47 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Period Pills for Menstrual Regulation: A New Reproductive Health Option

NCT07671989
View directory record Official record
Conditions
Menstrual Regulation, Menstrual Health Intervention
Interventions
Mifepristone + Misoprostol
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Oakland, California • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Mifepristone at Same Time Multicenter Study

NCT00269568
View directory record Official record
Conditions
Abortion Seekers
Interventions
mifepristone and misoprostol
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
1,128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
4
States / cities
Los Angeles, California • Chicago, Illinois • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Phase 3 Interventional Results available

Comparative Effectiveness of Pregnancy Failure Management Regimens

NCT02012491
View directory record Official record
Conditions
Spontaneous Abortion
Interventions
Misoprostol, Mifepristone
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
3
States / cities
Sacramento, California • The Bronx, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Self-Assessment of Medical Abortion Outcome Using Serial Multi-level Pregnancy Tests

NCT02570204
View directory record Official record
Conditions
Medical Abortion
Interventions
Self-assessment
Behavioral
Lead sponsor
Gynuity Health Projects
Other
Eligibility
11 Years to 56 Years · Female only
Enrollment
343 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
3
States / cities
West Palm Beach, Florida • Chevy Chase, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2017 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Not applicable Interventional Results available

Foley Bulb With Oral Misoprostol for Induction of Labor

NCT03407625
View directory record Official record
Conditions
Pregnancy, Labor, Induced
Interventions
Foley bulb plus Oral Misoprostol, Oral Misoprostol
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
10 Years and older · Female only
Enrollment
2,227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Sep 5, 2026, 7:47 AM EDT
Completed No phase listed Observational

Labor Induction With Oral Versus Vaginal Misoprostol

NCT04755218
View directory record Official record
Conditions
Pregnancy, Labor, Induced
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
10 Years and older · Female only
Enrollment
2,546 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Sep 5, 2026, 7:47 AM EDT
Recruiting Early Phase 1 Interventional

Induction of Labor in Morbidly Obese Patients

NCT06199154
View directory record Official record
Conditions
Morbid Obesity, Pregnancy
Interventions
Misoprostol
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older · Female only
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Randomized Trial Comparing Misoprostol and Foley Bulb for Pregnancy Termination in the Second Trimester

NCT00324519
View directory record Official record
Conditions
Pregnancy Trimester, Second, Induced Abortion
Interventions
Foley bulb, misoprostol
Device · Drug
Lead sponsor
University of Florida
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 4, 2012 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness Trial

NCT02639429
View directory record Official record
Conditions
Obesity, Labor Induction, Cesarean Delivery
Interventions
Vaginal Misoprostol, Foley Balloon + Vaginal Misoprostol
Drug · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
236 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2019 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Misoprostol Versus Dilapan-S for Cervical Preparation

NCT00835731
View directory record Official record
Conditions
Cervical Ripening
Interventions
misoprostol, Dilapan-S, vitamin B-12
Drug · Device
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2017 · Synced Sep 5, 2026, 7:47 AM EDT
Recruiting Not applicable Interventional

Ripening Approaches for Prompt Induction and Delivery - Sequential Versus Concurrent Dilapan-S and Misoprostol to Achieve Vaginal Delivery (RAPID-DS)

NCT07717502
View directory record Official record
Conditions
Nulliparous Women Who Scheduled for Labor Induction, Pregnancy
Interventions
Sequential Cervical Ripening, Inpatient Combined Cervical Ripening
Combination Product
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 5, 2026, 7:47 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Labor Protocol Study

NCT04004845
View directory record Official record
Conditions
Vaginal Delivery, Labor, Induced; Birth
Interventions
Cytotec, oxytocin, Cervical Foley Balloon
Drug · Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Sep 5, 2026, 7:47 AM EDT
Completed No phase listed Observational

Misoprostol for Spinal Stenosis

NCT04611464
View directory record Official record
Conditions
Lumbar Spinal Stenosis, Low Back Pain
Interventions
Misoprostol
Drug
Lead sponsor
Dallas VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2020 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Immune Modulation by Misoprostol

NCT02259309
View directory record Official record
Conditions
Gynecological Infection
Interventions
Misoprostol - buccal, Misoprostol - vaginal
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Phase 3 Interventional Results available

Safety/Efficacy Study Comparing the Misoprostol Vaginal Insert to Cervidil for Cervical Ripening and Induction of Labor

NCT00308711
View directory record Official record
Conditions
Cervical Ripening, Labor, Induced
Interventions
Misoprostol vaginal insert 100 mcg, Misoprostol vaginal insert 50 mcg, Dinoprostone vaginal insert (Cervidil)
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
49
States / cities
Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 43 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2012 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management With Medication Abortion Through 70 Days' Gestation

NCT03925129
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
high frequency TENS treatment, Sham TENS treatment
Device
Lead sponsor
Planned Parenthood of Greater New York
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Sep 5, 2026, 7:47 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Assessing Medical Menstrual Regulation in the United States

NCT03972358
View directory record Official record
Conditions
Menstrual Regulation
Interventions
Mifepristone, Misoprostol
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
284 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Skokie, Illinois • Chevy Chase, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 23, 2021 · Synced Sep 5, 2026, 7:47 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The Extended Gestational Age Medical Abortion Study

NCT00997347
View directory record Official record
Conditions
Medical Abortion
Interventions
Mifepristone and misoprostol
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
18 Years and older · Female only
Enrollment
1,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
6
States / cities
West Palm Beach, Florida • Chicago, Illinois • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2012 · Synced Sep 5, 2026, 7:47 AM EDT