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ClinicalTrials.gov public records Last synced Oct 27, 2026, 6:22 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 865–888 of 1,039 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: negative control Clear all
Completed No phase listed Observational

COVID-19 Pregnancy Related Immunological, Clinical and Epidemiological Factors and Perinatal Outcomes

NCT04659759
View directory record Official record
Conditions
Covid19
Interventions
COVID-19 exposure, COVID-19 vaccine
Other · Biological
Lead sponsor
Thomas Jefferson University
Other
Eligibility
Female only
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 27, 2026, 6:22 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Phase 2 Study of AMG 386 Plus Paclitaxel With or Without Bevacizumab as First Line Therapy in Her2-Negative Breast Cancer Patients

NCT00511459
View directory record Official record
Conditions
Locally Recurrent and Metastatic Breast Cancer
Interventions
AMG 386 Placebo, AMG 386, Bevacizumab, Paclitaxel
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years and older · Female only
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
26
States / cities
Litchfield Park, Arizona • Tucson, Arizona • Hot Springs, Arkansas + 23 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2015 · Synced Oct 27, 2026, 6:22 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

HIV-1 Vaccine Test in Uninfected Adult Volunteers

NCT00045838
View directory record Official record
Conditions
Healthy
Interventions
VCR-HIVDNA006-00-VP
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 2, 2015 · Synced Oct 27, 2026, 6:22 AM EDT
Terminated Phase 3 Interventional Results available

SPD489 Low Dose and High Dose Ranges When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia

NCT01760889
View directory record Official record
Conditions
Schizophrenia
Interventions
SPD489 low dose range (40mg, 80mg, and 100mg), SPD489 high dose range (120mg, 140mg and 160mg), Placebo
Drug
Lead sponsor
Shire
Industry
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
4
States / cities
Miami Springs, Florida • O'Fallon, Missouri • Saint Charles, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2021 · Synced Oct 27, 2026, 6:22 AM EDT
Not yet recruiting Not applicable Interventional

Quadratus Lumborum Versus Placebo in Open Ventral Hernia Repair

NCT06953635
View directory record Official record
Conditions
Hernia, Ventral, Pain Management
Interventions
Quadratus Lumborum (QL) Block, Placebo
Procedure
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 1, 2025 · Synced Oct 27, 2026, 6:22 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

R4Power: An Online Resilience Program for Adolescents

NCT00641368
View directory record Official record
Conditions
Depression, Anxiety
Interventions
R4Power Program, Waitlist Control
Behavioral · Other
Lead sponsor
Swarthmore College
Other
Eligibility
11 Years to 15 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Swarthmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2008 · Synced Oct 27, 2026, 6:22 AM EDT
Completed Not applicable Interventional Results available

The Effect of Questionnaire Content on Measures of Pain Intensity, Magnitude of Disability, and Symptoms of Depression in Patients With Arm Illness

NCT02209259
View directory record Official record
Conditions
Arm Illness
Interventions
PROMIS Upper Extremity Function, Pain intensity, PROMIS depression, Positive affect negative affect scale (PANAS), standard PCS, positively-adjusted version of the PCS
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 14, 2018 · Synced Oct 27, 2026, 6:22 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Thinking and Memory Problems in People With HIV

NCT01875588
View directory record Official record
Conditions
HIV Positive
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 110 Years
Enrollment
1,150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 27, 2026, 6:22 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Enhanced Recovery Strategies in Elective Breast Surgery

NCT03187080
View directory record Official record
Conditions
Pain, Acute, Nausea, Vomiting, Postoperative, Opioid Use, Satisfaction
Interventions
Paravertebral block procedure using either local anesthetic (0.25% bupivacaine) or sterile saline, Enhanced recovery after breast surgery (ERABS) strategies, Sham paravertebral block using saline, Paravertebral block using local anesthetic
Procedure · Other · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 23, 2024 · Synced Oct 27, 2026, 6:22 AM EDT
Completed Phase 2Phase 3 Interventional Results available

A Study of the Experimental Drug BKM120 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer, With or Without PI3K Activation

NCT01572727
View directory record Official record
Conditions
Breast Cancer
Interventions
Paclitaxel, BKM120 matching placebo, BKM120
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older · Female only
Enrollment
416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
21
States / cities
Chandler, Arizona • Phoenix, Arizona • Fayetteville, Arkansas + 17 more
Source: ClinicalTrials.gov public record
Updated Mar 9, 2017 · Synced Oct 27, 2026, 6:22 AM EDT
Not yet recruiting Not applicable Interventional

A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior

NCT06686901
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt
Interventions
Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S), Smartphone-delivered inactive Therapeutic Evaluative Conditioning
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 27, 2026, 6:22 AM EDT
Completed Not applicable Interventional

MANAGE AT WORK: Addressing the Challenge of Chronic Physical Health Conditions in the Workplace

NCT01978392
View directory record Official record
Conditions
Chronic Physical Health Conditions
Interventions
Self-management group workshops
Behavioral
Lead sponsor
Liberty Mutual Research Institute for Safety
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
4
States / cities
Worcester, Massachusetts • Hanover, New Hampshire • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 2, 2017 · Synced Oct 27, 2026, 6:22 AM EDT
Completed Phase 2Phase 3 Interventional

Health Interventions for Survivors and Primary Support Persons of Spinal Cord Injury

NCT00148239
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Caregiver Only Intervention, Dual Treatment, Control
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
30 Years and older
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
2
States / cities
Miami, Florida • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Oct 27, 2026, 6:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Clinical Bite Force Study of Two Marketed Adhesives Against no Adhesive

NCT03037307
View directory record Official record
Conditions
Denture Retention
Interventions
Test Product, Positive Contol, Negative Control
Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 85 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 27, 2026, 6:22 AM EDT
Recruiting Not applicable Interventional

Reducing Surgical Site Infection Rates Using an Alternative Sternal Dressing

NCT03346694
View directory record Official record
Conditions
Wound of Skin
Interventions
Standard Island Dressing, Prevena Negative Pressure wound dressing, Mepilex Border Post-Op Ag
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
660 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2035
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2022 · Synced Oct 27, 2026, 6:22 AM EDT
Recruiting Not applicable Interventional

Personalized Addiction Treatment enHancement

NCT07778394
View directory record Official record
Conditions
Opioid Use Disorder, mHealth, Peer Support
Interventions
Vira Platform, Treatment-As-Usual
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
22 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 27, 2026, 6:22 AM EDT
Completed Not applicable Interventional

Impact of Pre-Sedation Virtual Reality Game on Post-Discharge Negative Behaviors in the Pediatric Emergency Department

NCT03980067
View directory record Official record
Conditions
Behavior, Child, Anxiety
Interventions
Virtual Reality Game
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
6 Years to 17 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 27, 2026, 6:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Local Anesthetics

NCT01402869
View directory record Official record
Conditions
Methemoglobinemia
Interventions
4% prilocaine plain, 2% Lidocaine with 1:100,000 epinephrine
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
3 Years to 5 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Apr 25, 2014 · Synced Oct 27, 2026, 6:22 AM EDT
Completed No phase listed Observational

Long-Term Sequelae of SARS-COV-2 Infection: Diabetes Mellitus

NCT05867017
View directory record Official record
Conditions
COVID-19, Diabete Mellitus
Interventions
Measure of physiologic parameters
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 75 Years
Enrollment
23 participants
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 27, 2026, 6:22 AM EDT
Completed Not applicable Interventional

Developing a Low-Intensity Primary Care Intervention for Anxiety Disorders

NCT02266446
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Attention & Interpretation Modification
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Pawtucket, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 23, 2018 · Synced Oct 27, 2026, 6:22 AM EDT
Completed Not applicable Interventional

Process and Outcomes in CBT for Anxious and Depressed Youth

NCT03100279
View directory record Official record
Conditions
Anxiety Disorders, Depression
Interventions
Coping Cat/CAT Project, Primary and Secondary Coping Enhancement Therapy
Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
7 Years to 17 Years
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2020
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 27, 2026, 6:22 AM EDT
Completed Not applicable Interventional

Modafinil Augmentation Therapy for Excessive Daytime Sleepiness and Negative Symptoms in Patients With Schizophrenia

NCT00546403
View directory record Official record
Conditions
Schizophrenia
Interventions
Modafinil, Placebo
Drug
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2009 · Synced Oct 27, 2026, 6:22 AM EDT
Recruiting Phase 2 Interventional

Enhanced Pain Coping in Cancer (EPIC): A Study of Managing Treatment-Related Joint Pain in Breast Cancer Survivors

NCT06728579
View directory record Official record
Conditions
Breast Cancer Survivor
Interventions
Mindfulness Oriented Recovery Enhancement (MORE), Questionnaires, Supportive Psychotherapy (SG)
Behavioral · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
9
States / cities
San Diego, California • Tallahassee, Florida • Basking Ridge, New Jersey + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 27, 2026, 6:22 AM EDT
Completed Phase 2 Interventional Results available

A Study to Learn About the Study Medicine PF-07220060 Together With Letrozole Compared to Letrozole Alone in Women Post Menopause

NCT06465368
View directory record Official record
Conditions
Breast Cancer
Interventions
PF-07220060, letrozole
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older · Female only
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
10
States / cities
Barrington, Illinois • Crystal Lake, Illinois • Park Ridge, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 27, 2026, 6:22 AM EDT