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ClinicalTrials.gov public records Last synced Oct 3, 2026, 4:18 PM EDT

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Showing 25–48 of 291 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: oxytocin (Pitocin) Clear all
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Oxytocin Treatment of Alcohol Dependence

NCT02251912
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Intranasal Oxytocin, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Oct 3, 2026, 4:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Somatic Psychoeducational Intervention

NCT06580119
View directory record Official record
Conditions
Work Related Stress
Interventions
Somatic Psychoeducational Intervention
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 3, 2025 · Synced Oct 3, 2026, 4:18 PM EDT
Completed Phase 2 Interventional

A Randomized, Control Trial for Preinduction Cervical Ripening

NCT00393731
View directory record Official record
Conditions
Labor, Induced
Interventions
Misoprostol, oxytocin
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Female only
Enrollment
540 participants
Timeline
2004 – 2007
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 16, 2008 · Synced Oct 3, 2026, 4:18 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Oxytocin Receptor Expression in Pregnancy

NCT03907735
View directory record Official record
Conditions
Post-Abortion, Hemorrhage, Obstetric
Interventions
Myometrial tissue sample collection
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 31, 2025 · Synced Oct 3, 2026, 4:18 PM EDT
Completed Not applicable Interventional

Adjuvant Oxytocin for Preinduction Ripening With a Foley catheter--a Clinical Trial

NCT00468520
View directory record Official record
Conditions
Pregnancy, Induced Labor, Cervical Ripening
Interventions
low dose oxytocin
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2011 · Synced Oct 3, 2026, 4:18 PM EDT
Completed Not applicable Interventional Results available

Outpatient Foley For Starting Induction of Labor at TErm

NCT02756689
View directory record Official record
Conditions
Pregnancy
Interventions
Inpatient cervical ripening, Outpatient cervical ripening
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Oct 3, 2026, 4:18 PM EDT
Terminated Phase 3 Interventional Results available

High Dose Oxytocin Nasal Spray for Treatment of Tinnitus

NCT04210310
View directory record Official record
Conditions
Tinnitus
Interventions
Oxytocin, Placebo nasal spray
Drug · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 75 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Oct 3, 2026, 4:18 PM EDT
Recruiting Phase 2Phase 3 Interventional

Anticholinergics for Cervical Edema in Labor

NCT06702670
View directory record Official record
Conditions
Labor Dystocia
Interventions
Treatment with Diphenhydramine, Usual Care
Drug · Combination Product
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 3, 2026, 4:18 PM EDT
Recruiting Phase 2 Interventional

Oxytocin Effects on Bone in Children With Autism Spectrum Disorder

NCT05754073
View directory record Official record
Conditions
Autism Spectrum Disorder, Bone Health
Interventions
1. Intranasal oxytocin spray, 2. Intranasal placebo spray, 3. Intranasal Oxytocin spray
Drug
Lead sponsor
Elizabeth Austen Lawson
Other
Eligibility
6 Years to 18 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 3, 2026, 4:18 PM EDT
Completed Phase 2 Interventional Results available

Intranasal Oxytocin vs. Placebo for the Treatment of Hyperphagia in Prader-Willi Syndrome

NCT03197662
View directory record Official record
Conditions
Prader-Willi Syndrome, Hyperphagia
Interventions
Intranasal Oxytocin (IN-OXT), Matched Placebo
Drug
Lead sponsor
Eric Hollander
Other
Eligibility
5 Years to 17 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 7, 2025 · Synced Oct 3, 2026, 4:18 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Brain Dynamics of Oxytocin

NCT01834261
View directory record Official record
Conditions
Brain Dynamics in Healthy Adults
Interventions
Syntocinon Nasal Spray, 40IU, Syntocinon Placebo Formulation, 40IU
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 45 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
3
States / cities
Cambridge, Massachusetts • Charlestown, Massachusetts • Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2017 · Synced Oct 3, 2026, 4:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized Controlled Trial to Improve Mother-Infant Synchrony Among Women With Childhood Adversity

NCT04818112
View directory record Official record
Conditions
Parent-Child Relations, Maternal Behavior, Infant Behavior
Interventions
ATVV, Attention control
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older · Female only
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Oct 3, 2026, 4:18 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Relationship Between Oxytocin Level, Trust, and Attachment in Individuals With Borderline Personality Disorder

NCT06045650
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
baseline serum oxytocin levels, Emotional Sensitivity test, Neuro-economical game, Childhood Trauma Questionnaire, Relationships Questionnaire, demographic questionnaire
Other
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated May 24, 2024 · Synced Oct 3, 2026, 4:18 PM EDT
Recruiting Phase 2 Interventional

A Study of the Effects of Oxytocin in Adults With Binge-eating Disorder

NCT05664516
View directory record Official record
Conditions
Binge-eating Disorder
Interventions
TNX-1900 (Tonix Pharmaceuticals), Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 3, 2026, 4:18 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Methadone Oxytocin Option

NCT01728909
View directory record Official record
Conditions
Substance Abuse, Opioid Dependence, Methadone Treatment
Interventions
Oxytocin, Saline Nasal Spray
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 21, 2019 · Synced Oct 3, 2026, 4:18 PM EDT
Completed Not applicable Interventional Results available

Does Acute Oxytocin Administration Enhance Social Cognition in Individuals With Schizophrenia?

NCT01312272
View directory record Official record
Conditions
Schizophrenia
Interventions
Oxytocin, Inactive placebo nasal spray
Drug
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
18 Years to 55 Years · Male only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 2, 2014 · Synced Oct 3, 2026, 4:18 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Prenatal Cocaine, Nasal Oxytocin, and Maternal Psychophysiology

NCT02872467
View directory record Official record
Conditions
Substance Abuse Problem, Pregnancy
Interventions
Syntocinon treatment, Placebo
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 3, 2026, 4:18 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Inpatient Versus Outpatient Cervical Ripening

NCT03769610
View directory record Official record
Conditions
Pregnancy Related, Labor, Induction, Cervical Ripening
Interventions
Inpatient Foley catheter, Outpatient Foley catheter
Other
Lead sponsor
LifeBridge Health
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
2
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Oct 3, 2026, 4:18 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study of Wellness Behaviors as a Function of Oxytocin vs Placebo

NCT01929161
View directory record Official record
Conditions
Sustained Positive Emotions, Sustained Positive Behavior Change
Interventions
Oxytocin, Placebo (for oxytocin), Lovingkindness Meditation, Mindfulness Meditation
Drug · Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
35 Years to 64 Years
Enrollment
239 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 18, 2016 · Synced Oct 3, 2026, 4:18 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluation of MDMA on Startle Response

NCT03181763
View directory record Official record
Conditions
Startle Response
Interventions
Placebo, Midomafetamine, Acoustic startle
Drug · Behavioral
Lead sponsor
Resilient Pharmaceuticals
Industry
Eligibility
21 Years to 55 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Oct 3, 2026, 4:18 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

The Effect of Oxytocin Administration on Interpersonal Cooperation in Borderline Personality Disorder Patients and Healthy Adults

NCT02225600
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
40 IU Intranasal Oxytocin, Placebo, 24 IU intranasal Oxytocin
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 3, 2026, 4:18 PM EDT
Completed Phase 2 Interventional Results available

Oxytocin, Alcohol Craving, and Intimate Partner Aggression

NCT03046836
View directory record Official record
Conditions
Alcohol Use
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 3, 2026, 4:18 PM EDT
Terminated Phase 2 Interventional Results available

Efficacy of Intrathecal Oxytocin to Speed Recovery After Hip Surgery

NCT03011307
View directory record Official record
Conditions
Postoperative Pain
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 23, 2022 · Synced Oct 3, 2026, 4:18 PM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Validate a Pharmacodynamic Model of Oxytocin for Peripheral Analgesic Effects

NCT04435704
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Oxytocin
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 3, 2026, 4:18 PM EDT