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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:58 AM EDT

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Showing 25–48 of 235 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: pacemaker Clear all
Completed Not applicable Interventional Results available

Effect of Chronic Changes in Heart Rate on Congestive Heart Failure

NCT00389649
View directory record Official record
Conditions
Heart Failure, Congestive
Interventions
heart rate setting
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 20, 2021 · Synced Oct 21, 2026, 5:58 AM EDT
Completed Not applicable Interventional

Personalized Pacing: A New Paradigm for Patients With Diastolic Dysfunction or Heart Failure With Preserved Ejection Fraction

NCT04721314
View directory record Official record
Conditions
Pacemaker, Diastolic Dysfunction, Diastolic Heart Failure
Interventions
Adjustment of lower rate limit, Maintenance of lower rate limit
Device
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 9, 2022 · Synced Oct 21, 2026, 5:58 AM EDT
Terminated Not applicable Interventional Results available

Comparison of Cyanoacrylate Tissue Adhesive and Suture for Closure of Cardiac Device Pockets

NCT00674128
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Cyanoacrylate tissue adhesive (Dermabond), Polyglactin 910 suture (Vicryl)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 29, 2010 · Synced Oct 21, 2026, 5:58 AM EDT
Completed No phase listed Observational

Long-Term Results of DDD Pacing in Obstructive Hypertrophic Cardiomyopathy

NCT00001530
View directory record Official record
Conditions
Cardiomyopathy, Hypertrophic
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 21, 2026, 5:58 AM EDT
Completed Not applicable Interventional Results available

Cardiac Resynchronization in the Elderly

NCT03031847
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy Pacemaker, Cardiac Resynchronization Therapy Defibrillator
Device
Lead sponsor
Samir Saba
Other
Eligibility
75 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
6
States / cities
Durham, North Carolina • Columbus, Ohio • Erie, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2023 · Synced Oct 21, 2026, 5:58 AM EDT
Recruiting Not applicable Interventional

VAPORHCS/OHSU J: MRI and Devices

NCT03915015
View directory record Official record
Conditions
MRI
Interventions
MRI
Diagnostic Test
Lead sponsor
Oregon Health and Science University
Other
Eligibility
9 Years to 99 Years
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2030
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Oct 21, 2026, 5:58 AM EDT
Recruiting No phase listed Observational

His Bundle Pacing in Bradycardia and Heart Failure

NCT03008291
View directory record Official record
Conditions
Bradycardia, Heart Failure
Interventions
CRT-D Implantation, CRT-P Implantation, Dual Chamber Pacemaker Implantation
Procedure
Lead sponsor
Yong-Mei Cha
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 21, 2026, 5:58 AM EDT
Terminated Not applicable Interventional Results available

MIRACLE EF Clinical Study

NCT01735916
View directory record Official record
Conditions
Congestive Heart Failure, Left Bundle Branch Block, Systolic Heart Failure
Interventions
CRT-P Implant, CRT-P OFF
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
69
States / cities
Concord, California • La Jolla, California • Los Angeles, California + 62 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Oct 21, 2026, 5:58 AM EDT
Completed Not applicable Interventional

Postcards to Improve Remote Monitoring Adherence Among Veterans

NCT06068699
View directory record Official record
Conditions
ICD, Pacemaker DDD, Adherence, Patient
Interventions
Postcard
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
6,351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced Oct 21, 2026, 5:58 AM EDT
Completed Not applicable Interventional Results available

Randomized Study of the Use of Warfarin During Pacemaker or ICD Implantation in Patients Requiring Long Term Anticoagulation

NCT00721136
View directory record Official record
Conditions
Bradycardia, Tachycardia, Atrial Fibrillation, Valvular Heart Disease
Interventions
continue warfarin through the procedure, Hold warfarin, Warfarin held with heparin transition.
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Baltimore, Maryland • Columbia, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 21, 2026, 5:58 AM EDT
Completed No phase listed Observational

The Atrial High Rate Episodes in Pacemaker Patients

NCT00627328
View directory record Official record
Conditions
Arrhythmia, Atrial Fibrillation, Atrioventricular Block, Bradycardia, Sick Sinus Syndrome
Interventions
Not listed
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
50 Years and older
Enrollment
427 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
37
States / cities
Hot Springs, Arkansas • Little Rock, Arkansas • Fresno, California + 34 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Oct 21, 2026, 5:58 AM EDT
Completed Phase 3 Interventional

SITELINE 2 Polyurethane

NCT00180284
View directory record Official record
Conditions
Bradycardia
Interventions
SITELINE 2 Polyurethane (pacing lead)
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 29, 2011 · Synced Oct 21, 2026, 5:58 AM EDT
Completed No phase listed Observational Results available

Imaging Study of Lead Implant for His Bundle Pacing

NCT03294317
View directory record Official record
Conditions
Cardiac Pacemaker, Artificial
Interventions
His bundle pacing
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Indianapolis, Indiana • Wilkes-Barre, Pennsylvania • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 1, 2021 · Synced Oct 21, 2026, 5:58 AM EDT
Enrolling by invitation Not applicable Interventional

Magnetic Resonance Imaging (MRI) in Patients With Pacemakers and Implanted Cardioverter Defibrillators

NCT02888353
View directory record Official record
Conditions
Device:MRI
Interventions
Device: MRI
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
9 Years to 100 Years
Enrollment
4,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 21, 2026, 5:58 AM EDT
Not listed Not applicable Interventional

Comparison of Physiologic Response With Rate Adaptive Pacing Driven by Minute Ventilation and Accelerometer

NCT02003378
View directory record Official record
Conditions
Chronotropic Incompetence
Interventions
Pacemaker sensor set to MV, Pacemaker sensor set to XL
Device
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Dec 6, 2013 · Synced Oct 21, 2026, 5:58 AM EDT
Completed No phase listed Observational Results available

REPLACE: Implantable Cardiac Pulse Generator Replacement Registry

NCT00395447
View directory record Official record
Conditions
Device Replacement, Elective Replacement (ERI), Device Advisory, Device Upgrade, Postoperative Complications
Interventions
Straight-forward Device Replacement, Device Replacement with Upgrade
Procedure
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,744 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
71
States / cities
Birmingham, Alabama • Mesa, Arizona • Modesto, California + 58 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Oct 21, 2026, 5:58 AM EDT
Withdrawn Not applicable Interventional

The Effect of Yoga on Cardiac Sympathetic Innervation Evaluated by I-123 mIBG

NCT03227393
View directory record Official record
Conditions
Heart Failure, Systolic
Interventions
Yoga training
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 20, 2018 · Synced Oct 21, 2026, 5:58 AM EDT
Not yet recruiting Not applicable Interventional

Early Feasibility Study of 3830 Lead Implantation Via the Middle Cardiac Vein in Patients With Prior or Planned Tricuspid Valve Intervention

NCT07805525
View directory record Official record
Conditions
Cardiac Conduction Disorders Requiring Permanent Pacing in Patients With Prior or Planned Tricuspid Valve Intervention
Interventions
Pacemaker
Device
Lead sponsor
Minneapolis Heart Institute Foundation
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 21, 2026, 5:58 AM EDT
Completed Not applicable Interventional

Dynamic Laryngeal Opening for Bilateral Vocal Fold Paralysis by an Implanted Stimulator

NCT00845442
View directory record Official record
Conditions
Vocal Cord Paralysis
Interventions
pacemaker
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 22, 2022 · Synced Oct 21, 2026, 5:58 AM EDT
Recruiting No phase listed Observational

Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)

NCT06641362
View directory record Official record
Conditions
Bradycardia, Heart Failure, Ventricular Dysfunction
Interventions
Ultra High Frequency Electrocardiogram (UHF-ECG)
Device
Lead sponsor
VDI Technologies
Industry
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
7
States / cities
Avondale, Arizona • Mesa, Arizona • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 21, 2026, 5:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prospective Observation of Exercise Parameters in Advanced Heart Failure

NCT01210573
View directory record Official record
Conditions
Advanced Heart Failure
Interventions
adjustment of LVAD or pacemaker
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 18, 2014 · Synced Oct 21, 2026, 5:58 AM EDT
Completed Not applicable Interventional Results available

Micra Transcatheter Pacing Study

NCT02004873
View directory record Official record
Conditions
Class I or II Indication for Implantation of a Single Chamber Ventricular Pacemaker According to ACC/AHA/HRS 2001 Guidelines and Any National Guidelines
Interventions
Micra Pacemaker Implant
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
744 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
30
States / cities
La Jolla, California • Los Angeles, California • New Haven, Connecticut + 26 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Oct 21, 2026, 5:58 AM EDT
Not yet recruiting Not applicable Interventional

PACE Cognition Proof-of-Concept Study

NCT07769424
View directory record Official record
Conditions
Symptomatic Bradycardia, Cognitive Function, Pacemaker, Health Status
Interventions
Physiologic Pacemaker Programming, Standard Pacemaker Programming
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 21, 2026, 5:58 AM EDT
Completed Not applicable Interventional Results available

Reducing Episodes by Septal Pacing Efficacy Confirmation Trial (RESPECT)

NCT00289289
View directory record Official record
Conditions
Atrial Fibrillation, Tachycardia, Supraventricular, Arrhythmia, Bradycardia
Interventions
Intervention Pacing Features
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
34
States / cities
Little Rock, Arkansas • Rancho Mirage, California • San Diego, California + 31 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2012 · Synced Oct 21, 2026, 5:58 AM EDT