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ClinicalTrials.gov public records Last synced Oct 19, 2026, 2:35 PM EDT

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Showing 1–24 of 169 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: prebiotic Clear all
Completed Phase 1 Interventional Results available

Effect of Prebiotics on the Gut Microbiome Profile and Beta Cell Function

NCT04114357
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Acetylated and Butyrylated High Amylose Maize Starch
Drug
Lead sponsor
Indiana University
Other
Eligibility
11 Years to 17 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional Results available

Probiotic Therapy for Children and Adults With Autism Spectrum Disorder

NCT04655326
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Flore
Dietary Supplement
Lead sponsor
Arizona State University
Other
Eligibility
30 Months to 75 Years
Enrollment
296 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 19, 2026, 2:35 PM EDT
Not yet recruiting Not applicable Interventional

Comparing Prebiotic Fiber Supplements for Gut Health and Digestive Comfort

NCT07525180
View directory record Official record
Conditions
Healthy Participants
Interventions
LOAM, Inulin, Cellulose Placebo
Dietary Supplement
Lead sponsor
Ventoscity LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional

Effect of a Comprehensive Nutrition Support Product on the Nutritional Status of Adults With Inflammatory Bowel Disease

NCT02801240
View directory record Official record
Conditions
Colitis, Ulcerative, Crohn's Disease
Interventions
Nutrition support product
Other
Lead sponsor
National University of Natural Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 14, 2018 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Phage 3Determination of Phage/Probiotic Synergistic Effects on Gastrointestinal Health

NCT05750433
View directory record Official record
Conditions
Gastrointestinal Dysfunction
Interventions
PreforPro+B. subtilis DE111 probiotics, Placebo, B. subtilis DE111
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 27, 2024 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Growth of Infants Fed New Starter Formula

NCT01079208
View directory record Official record
Conditions
Dietary Intervention
Interventions
test starter infant formula, test starter infant formula with synbiotics, control standard formula
Other
Lead sponsor
Société des Produits Nestlé (SPN)
Industry
Eligibility
11 Days to 6 Months
Enrollment
297 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
3
States / cities
San Francisco, California • Orlando, Florida • Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 3, 2014 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional

Efficacy of Evidence-Based PTSD Treatment Via Prebiotic Supplementation

NCT05424146
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Prebiotic Bar +CPT, Non-Prebiotic Bar +CPT
Dietary Supplement · Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Oct 19, 2026, 2:35 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Irritable Bowel Syndrome and Control Volunteers: Diet Challenge

NCT03983434
View directory record Official record
Conditions
IBS - Irritable Bowel Syndrome
Interventions
Inulin
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Effects of Xylooligosarcharide on Composition of the Human Colonic Microflora

NCT01861964
View directory record Official record
Conditions
Bifidobacteria, Healthy Volunteers
Interventions
Placebo (Maltodextrin), Xylooligosarcharide 1.4g, Xylooligosarcharide 2.8g
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
20 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 28, 2016 · Synced Oct 19, 2026, 2:35 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Assessing the Short-Term Effects of Multi-Fiber Supplementation on Gut Health

NCT07787026
View directory record Official record
Conditions
Mixed Fiber Supplementation for Healthy Adults
Interventions
Prebiotic, Placebo
Dietary Supplement
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Phase 4 Interventional Results available

Vitamin D and Prebiotics for Intestinal Health in Cystic Fibrosis

NCT04118010
View directory record Official record
Conditions
Cystic Fibrosis, Dysbiosis
Interventions
Vitamin D3, Placebo vitamin D3, Inulin, Placebo Inulin
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Microbiome and Resilience to Sleep and Circadian Disruption

NCT03747367
View directory record Official record
Conditions
Sleep Deprivation, Circadian Dysregulation, Stress
Interventions
Insufficient Sleep, Prebiotic, Placebo
Behavioral · Dietary Supplement
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 45 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional

The Use of A Prebiotic to Promote a Healthy Gut Microbiome in Pediatric Stem Cell Transplant Recipients

NCT04111471
View directory record Official record
Conditions
Microbial Colonization
Interventions
Prebiotics, Placebos
Dietary Supplement
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
2 Years to 18 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gastrointestinal Tolerance of Infant Formula

NCT02322138
View directory record Official record
Conditions
Gastrointestinal Tolerance
Interventions
Experimental 1 Infant Formula, Experimental 2 Infant Formula, Reference Group
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
Up to 8 Days
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
10
States / cities
Tucson, Arizona • Colorado Springs, Colorado • Norwich, Connecticut + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2015 · Synced Oct 19, 2026, 2:35 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Multiomic Signatures of Microbial Metabolites Following Prebiotic Fiber Supplementation

NCT03925597
View directory record Official record
Conditions
Prebiotics
Interventions
Fiber cycles ARM 1, Fiber cycles ARM 2, Fiber cycles ARM 3, Fiber cycles ARM 4, Fiber cycles ARM 5, Fiber cycles ARM 6, Fiber cycles ARM 7, Fiber cycles ARM 8, Fiber cycles ARM 9, Fiber cycles ARM 10, Fiber cycles ARM 11, Fiber cycles ARM 12, Fiber cycles ARM 13, Fiber cycles ARM 14, Fiber cycles ARM 15, Fiber cycles ARM 16, Fiber cycles ARM 17, Fiber cycles ARM 18, Fiber cycles ARM 19, Fiber cycles ARM 20, Fiber cycles ARM 21, Fiber cycles ARM 22, Fiber cycles ARM 23, Fiber cycles ARM 24
Dietary Supplement
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional

Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCT

NCT04629430
View directory record Official record
Conditions
Multiple Myeloma, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Non Hodgkin Lymphoma, Acute Lymphocytic Leukemia, Hodgkin Lymphoma, Hodgkin Disease, Myelofibrosis, Myelodysplastic Syndromes, Myeloproliferative Neoplasm, Sickle Cell Disease, Mantle Cell Lymphoma
Interventions
Pre-biotic foods/drinks
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 4, 2023 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Study to Evaluate Efficacy and Tolerability of a Cosmetic Product for Arm Firming

NCT04065035
View directory record Official record
Conditions
Photodamaged Skin, Skin Care
Interventions
Topical Body Firming Moisturizer, Body Cleanser, Sunscreen, Placebo Moisturizer
Other
Lead sponsor
Revision Skincare
Industry
Eligibility
40 Years to 60 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Aug 22, 2019 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of a Prebiotic Blend in Healthy Humans

NCT07514741
View directory record Official record
Conditions
Healthy Adult Participants
Interventions
Fiber Blend 1 (Low Dose), Fiber Blend 2 (High Dose), Placebo
Dietary Supplement · Other
Lead sponsor
LOAM Science
Other
Eligibility
18 Years to 60 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
West Hollywood, California
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mercury Metabolism by Bacteria in Humans

NCT04060212
View directory record Official record
Conditions
Mercury--Toxicology
Interventions
Tuna fish, prebiotic
Other · Dietary Supplement
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Oct 19, 2026, 2:35 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Synbiotic to Attenuate Resorption of the Skeleton

NCT06389539
View directory record Official record
Conditions
Osteoporosis, Inflammation, Aging
Interventions
SBD111 medical food, Placebo
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
60 Years and older · Female only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Roslindale, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional Results available

Effect of Milk Oligosaccharides and Bifidobacteria on the Intestinal Microflora of Children With Autism

NCT02086110
View directory record Official record
Conditions
Autism
Interventions
Synbiotic, Prebiotic
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
2 Years to 11 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tolerability and Functional Assessment of a Novel Children's Synbiotic

NCT04534036
View directory record Official record
Conditions
Constipation, Signs and Symptoms, Digestive Signs and Symptoms, Infrequent or Difficult Evacuation
Interventions
PDS-08, Placebo
Dietary Supplement · Other
Lead sponsor
Seed Health
Industry
Eligibility
3 Years to 17 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 25, 2022 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional

Prebiotics, Gut Microbiota, and Cardiometabolic Health

NCT02346838
View directory record Official record
Conditions
Prediabetes
Interventions
Inulin, Placebo
Dietary Supplement
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
40 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 19, 2026, 2:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutritive Effects of Prebiotics on Early Postnatal Behavioral Measures of Tolerance

NCT02118935
View directory record Official record
Conditions
Behavioral Measures of Tolerance
Interventions
Previously marketed cow's mlik-based infant formula, Marketed cow's milk-based infant formula with prebiotics
Other
Lead sponsor
Mead Johnson Nutrition
Industry
Eligibility
14 Days to 35 Days
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
7
States / cities
Fayetteville, Arkansas • Norwich, Connecticut • Evansville, Indiana + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2016 · Synced Oct 19, 2026, 2:35 PM EDT