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ClinicalTrials.gov public records Last synced Sep 20, 2026, 8:22 PM EDT

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Showing 1–24 of 49 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Study of Neural Responses Induced by Antidepressant Effects

NCT02674529
Conditions
Major Depressive Disorder
Interventions
Escitalopram, Placebo, Real-time Neurofeedback fMRI task pre- and post-RCT
Drug · Behavioral
Lead sponsor
Marta Peciña, MD PhD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Not yet recruiting Phase 1Phase 2 Interventional

DecNef for AVH in Schizophrenia

NCT07779226
Conditions
Schizophrenia Disorder, Schizoaffecitve Disorder
Interventions
Decoded Neurofeedback
Device
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
New York, New York
Conditions
Cerebellar Ataxia, Spinocerebellar Ataxias, Cerebellar Degeneration
Interventions
Real-time fMRI with neurofeedback of motor imagery
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Terminated No phase listed Observational Accepts healthy volunteers

fMRI Neurofeedback for Motor Rehabilitation

NCT02089776
Conditions
Stroke, fMRI
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Major Depressive Disorder
Interventions
FMRI with sham controlled feedback, FMRI with real time feedback
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 55 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Post-Traumatic Stress Disorder in Adolescence
Interventions
Prism
Device
Lead sponsor
GrayMatters Health Ltd.
Industry
Eligibility
12 Years to 21 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Parent-Adolescent Training on Neurofeedback and Synchrony

NCT03929263
Conditions
Testing Protocol With Healthy Individuals for Feasibility
Interventions
Real-time fMRI neurofeedback
Behavioral
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
13 Years and older · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Tulsa, Oklahoma
Completed Not applicable Interventional Accepts healthy volunteers

Real Time fMRI and Quitting Smoking

NCT03302026
Conditions
Nicotine Use Disorder
Interventions
Realtime biofeedback using fMRI
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Stanford Center for Back Pain

NCT02503475
Conditions
Chronic Low Back Pain
Interventions
Real-Time fMRI, CBT or MBSR, Acupuncture
Other · Behavioral · Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Movement Disorder, Tourette Syndrome, Healthy Volunteer
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 60 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Terminated Not applicable Interventional Results available

Machine Learning Neurofeedback for PTSD

NCT03482466
Conditions
Post-traumatic Stress Disorder
Interventions
Neurofeedback
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 64 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Houston, Texas
Conditions
Major Depressive Disorder
Interventions
Amygdala real-time fMRI neurofeedback, Sham feedback
Device
Lead sponsor
Kymberly Young
Other
Eligibility
18 Years to 55 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Major Depressive Disorder
Interventions
real-time fMRI neurofeedback: Amygdala, real-time fMRI neurofeedback: HIPS
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tulsa, Oklahoma
Conditions
ADHD
Interventions
fMRI Neurofeedback attention task
Combination Product
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Brookline, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Real-time fMRI and Neurofeedback of Brain Networks Mediating Trauma Memory Recall in PTSD

NCT02500719
Conditions
Stress Disorders, Post-Traumatic
Interventions
Computational Model - Real-time Support Vector Machine
Device
Lead sponsor
University of Arkansas
Other
Eligibility
21 Years to 50 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Opioid Use Disorder, Substance Use Disorder, Heroin Use Disorder
Interventions
Real-time fMRI Neurofeedback, Sham Real-time fMRI Neurofeedback
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 64 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
New York, New York
Conditions
Healthy Participants
Interventions
Functional magnetic resonance imaging (fMRI)
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
PTSD, Cognitive Function
Interventions
Real-time functional magnetic resonance neurofeedback (rtfMRI-nf)
Other
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Conditions
Borderline Personality Disorder
Interventions
real time fMRI neurofeedback
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Terminated Not applicable Interventional Results available

Effects of Amygdala Neurofeedback on Depressive Symptoms

NCT02709161
Conditions
Major Depressive Disorder
Interventions
real-time fMRI neurofeedback: Amygdala, real-time fMRI neurofeedback: HIPS
Device
Lead sponsor
Kymberly Young
Other
Eligibility
18 Years to 55 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Post-Traumatic Stress Disorder
Interventions
Experimental Feedback, Control Feedback
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
New Haven, Connecticut • West Haven, Connecticut
Conditions
Healthy Volunteers, Alcohol Drinking Related Problems, Alcohol-Related Disorders
Interventions
Real time fMRI neurofeedback
Behavioral
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
21 Years to 65 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Healthy
Interventions
Neurofeedback treatment, At-home therapy
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Depression, Anxiety
Interventions
Active neurofeedback, Sham neurofeedback
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tulsa, Oklahoma