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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: tooth extraction Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Assessment of Bone Augmentation in Post-Extraction Sockets

NCT00641316
View directory record Official record
Conditions
Unrestorable Dentition, Post-Extraction Sockets
Interventions
AtraumaticTeeth Extraction, Atraumatic Teeth Extraction/Grafted Extraction Sockets
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Sep 10, 2026, 3:22 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Comparative Volumetric Assessment of Alveolar Ridge Preservation Utilizing Different Bone Grafting Materials

NCT02532543
View directory record Official record
Conditions
Tooth Fractures, Tooth Injuries, Tooth Diseases
Interventions
Allograft, Membrane, Alloplast, Membrane, Xenograft, Membrane, Membrane
Biological
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 8, 2019 · Synced Sep 10, 2026, 3:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Efficacy and Safety of a Loop Stretchable Dental Floss

NCT06515483
View directory record Official record
Conditions
Gingivitis, Supragingival Plaque
Interventions
Brushing and Flossing of teeth, Brushing Only
Device · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Sep 10, 2026, 3:22 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Cortical Shield for Facial Bone Reconstruction

NCT04827693
View directory record Official record
Conditions
Tooth Loss, Tooth Diseases, Tooth Fracture, Tooth Injuries, Periodontal Bone Loss, Periodontitis, Peri-Implantitis, Tooth Decay
Interventions
Not listed
Lead sponsor
Verdugo, Fernando, DDS
Individual
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 10, 2026, 3:22 PM EDT
Not yet recruiting No phase listed Observational

Post-Extraction Wound Healing in Elderly

NCT07796269
View directory record Official record
Conditions
Wound Healing
Interventions
tooth extraction
Procedure
Lead sponsor
University of Nebraska
Other
Eligibility
65 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 10, 2026, 3:22 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Use of Dental Pulp Tissue as an Autogenous Graft for Ridge Augmentation

NCT03943849
View directory record Official record
Conditions
Tooth Loss
Interventions
Particulate bone graft, Autogenous dental pulp tissue, Resorbable collagen membrane, Suture
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Sep 10, 2026, 3:22 PM EDT
Withdrawn Phase 2 Interventional

Maxi-Analgesic Phase 2 Study to Compare the Analgesic Effects in Different Dosing Groups to Treat Teeth Extraction Pain

NCT01104844
View directory record Official record
Conditions
Dental Pain
Interventions
Full Dose Strength, Quarter dose strength, Half dose strength, Acetaminophen standard dose, Ibuprofen low dose, Ibuprofen high dose, Placebo
Drug
Lead sponsor
AFT Pharmaceuticals, Ltd.
Industry
Eligibility
16 Years to 40 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 11, 2013 · Synced Sep 10, 2026, 3:22 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Diagnostic Device for the Assessment of Pulpal Blood Flow

NCT03578549
View directory record Official record
Conditions
Dental Pulp Test
Interventions
Pulse Oximetry
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 10, 2026, 3:22 PM EDT
Completed No phase listed Observational

Histologic Evaluation of Healing Following Tooth Extraction With Ridge Preservation Using NuOss XC and NuOss Particulate

NCT01391767
View directory record Official record
Conditions
Oral Ridge Preservation
Interventions
NuOss XC
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 64 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 7, 2013 · Synced Sep 10, 2026, 3:22 PM EDT
Completed Phase 2 Interventional

Study of Acetaminophen (ACE) in Post-operative Dental Pain

NCT02320708
View directory record Official record
Conditions
Dental Pain
Interventions
Acetaminophen (ACE) (1000 mg), Commercial ACE (1000 mg), Commercial Ibuprofen (IBU) (400 mg), Placebo
Drug
Lead sponsor
Johnson & Johnson Healthcare Products Division of McNEIL-PPC, Inc.
Industry
Eligibility
17 Years to 50 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 2, 2021 · Synced Sep 10, 2026, 3:22 PM EDT
Enrolling by invitation Not applicable Interventional

Alternatives to Dental Opioid Prescribing After Tooth Extraction

NCT06275191
View directory record Official record
Conditions
Analgesics, Opioid, Acute Pain, Tooth Extraction, Adolescent, Acetaminophen, Ibuprofen
Interventions
Multicomponent intervention, Usual care
Behavioral · Other
Lead sponsor
Douglas Oyler
Other
Eligibility
12 Years to 25 Years
Enrollment
38,159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 10, 2026, 3:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ridge Preservation Following Tooth Extraction Using Two Mineralized Cancellous Bone Allografts

NCT02515058
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
PUROS (Ridge Preservation bone grafting surgery), FDBA (Ridge Preservation bone grafting surgery)
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 89 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 10, 2026, 3:22 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Safety and Efficacy Study of XPF-001 to Treat Pain Following Wisdom Tooth Extraction

NCT00954356
View directory record Official record
Conditions
Dental Pain
Interventions
XPF-001, placebo
Drug
Lead sponsor
Xenon Pharmaceuticals Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 15, 2012 · Synced Sep 10, 2026, 3:22 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Aspirin Use and Postoperative Bleeding From Dental Extractions in a Healthy Population

NCT00405613
View directory record Official record
Conditions
Bleeding Complication
Interventions
Aspirin
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Sep 10, 2026, 3:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Osseodensification and Implant Survival and Success

NCT04741594
View directory record Official record
Conditions
Missing Teeth
Interventions
Densah
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 90 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 10, 2026, 3:22 PM EDT
Completed Phase 3 Interventional Results available

A Study to Assess the Efficacy and Tolerability of Diclofenac Potassium Soft Gelatin Capsules Compared With Ibuprofen Tablets in Patients With Moderate to Severe Postoperative Dental Pain

NCT02476422
View directory record Official record
Conditions
Post Operative Dental Pain
Interventions
Diclofenac potassium, Ibuprofen, Placebo to ibuprofen, Placebo to diclofenac potassium
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
328 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2016 · Synced Sep 10, 2026, 3:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Temporary Anchorage Devices for Ridge Preservation

NCT03205800
View directory record Official record
Conditions
Ridge Preservation
Interventions
Mini-screw
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced Sep 10, 2026, 3:22 PM EDT
Completed Phase 2 Interventional

Evaluation of a TNF-Alpha Modulator for Clinical and Molecular Indicators of Analgesic Effect

NCT00121563
View directory record Official record
Conditions
Pain
Interventions
Thalidomide, Ibuprofen or Diazepam
Drug
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
Male only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 10, 2026, 3:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Instrumentation Effectiveness of Modified, Area-Specific Hand Scalers During Non-Surgical Periodontal Therapy

NCT03729167
View directory record Official record
Conditions
Periodontal Diseases, Dental Diseases
Interventions
Scaling and root planing
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 17, 2019 · Synced Sep 10, 2026, 3:22 PM EDT
Completed Not applicable Interventional Results available

Bone Level Tapered Multi-Center Study

NCT02569671
View directory record Official record
Conditions
Tooth Loss
Interventions
Straumann Bone Level Tapered Implant - Immediate Placement, Straumann Bone Level Tapered Implant - Delayed Placement
Device
Lead sponsor
Institut Straumann AG
Industry
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
3
States / cities
Los Angeles, California • Gainesville, Florida • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 10, 2026, 3:22 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Comparing Inflammatory Markers in Patients With and Without Depression With Chronic Periodontitis

NCT03553095
View directory record Official record
Conditions
Chronic Periodontitis, Depression
Interventions
Periodontal Surgery
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Sep 10, 2026, 3:22 PM EDT
Completed Phase 2 Interventional

Rofecoxib to Prevent Pain After Third Molar (Wisdom Tooth) Extraction

NCT00026819
View directory record Official record
Conditions
Pain
Interventions
Rofecoxib
Drug
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 10, 2026, 3:22 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Zirconia Implants: Practice-based Evidence

NCT06314425
View directory record Official record
Conditions
Dental Implants, Ceramic Implant
Interventions
Immediate dental implants placements on fresh sockets after tooth extraction
Procedure
Lead sponsor
Swiss Dental Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Englewood Cliffs, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 10, 2026, 3:22 PM EDT
Completed Phase 3 Interventional Results available

Effect of Cyclic Loading (Vibration) on Orthodontic Tooth Movement

NCT00830947
View directory record Official record
Conditions
Malocclusion
Interventions
OrthoAccel Device, Sham Device
Device
Lead sponsor
OrthoAccel Technologies Inc.
Industry
Eligibility
12 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 22, 2013 · Synced Sep 10, 2026, 3:22 PM EDT