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ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:54 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 361–384 of 3,322 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: treatment as usual Clear all
Recruiting Phase 4 Interventional

Low-dose Buprenorphine Initiation for Opioid Use Disorder

NCT05450718
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
buprenorphine-naloxone
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 20, 2026, 2:54 AM EDT
Terminated Phase 3 Interventional Results available

Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS

NCT01482286
View directory record Official record
Conditions
Polycystic Ovary Syndrome
Interventions
Metformin, Dietary Restriction, Exercise Training
Drug · Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 15, 2022 · Synced Oct 20, 2026, 2:54 AM EDT
Completed Not applicable Interventional

Locomotor Recovery Following Traumatic Brain Injury

NCT04503473
View directory record Official record
Conditions
Traumatic Brain Injury (TBI)
Interventions
High Intensity Stepping Training, Conventional Therapy
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 75 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Oct 20, 2026, 2:54 AM EDT
Enrolling by invitation Not applicable Interventional

Algorithm-enabled Goals of Care Communication

NCT07690904
View directory record Official record
Conditions
Cancer
Interventions
Usual Care, Usual Care + Algorithm-enabled Goals of Care Communication (A-EPAC)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 20, 2026, 2:54 AM EDT
Completed Not applicable Interventional Results available

Lung Cancer Screening Navigation for Homeless People

NCT04308226
View directory record Official record
Conditions
Lung Cancer, Tobacco Use, Homelessness
Interventions
Patient Navigation
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
55 Years to 77 Years
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Oct 20, 2026, 2:54 AM EDT
Terminated Not applicable Interventional

Necessity of Anti-Arrhythmic Medication After Surgical Ablation for Atrial Fibrillation

NCT01416935
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
No Amiodarone
Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 20, 2022 · Synced Oct 20, 2026, 2:54 AM EDT
Recruiting Not applicable Interventional

Help Texts Grief Intervention for Bereaved College Students

NCT07228260
View directory record Official record
Conditions
Bereavement
Interventions
list of resources for grief, text-based intervention for grief
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 20, 2026, 2:54 AM EDT
Terminated Phase 3 Interventional Results available

Efficacy and Safety of Ramelteon Sublingual as Adjunctive Therapy for Maintenance Treatment of Bipolar I Disorder

NCT01467713
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Ramelteon SL, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 75 Years
Enrollment
642 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
138
States / cities
Birmingham, Alabama • Dothan, Alabama • Muscle Shoals, Alabama + 134 more
Source: ClinicalTrials.gov public record
Updated May 16, 2016 · Synced Oct 20, 2026, 2:54 AM EDT
Completed No phase listed Observational

A Pilot Study of Hypertension Management Using Remote Patient Monitoring

NCT04604925
View directory record Official record
Conditions
Hypertension
Interventions
Remote patient monitoring for hypertension
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
65 Years to 85 Years
Enrollment
7,068 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 15, 2022 · Synced Oct 20, 2026, 2:54 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Implementation Research to Increase Colorectal Cancer Screening Rates Among Low Income and Ethnic Minority Groups

NCT06090643
View directory record Official record
Conditions
Colorectal Carcinoma
Interventions
Best Practice, Consultation, Educational Intervention, Electronic Health Record Review, Fecal Immunochemical Test, Feedback, Health Education, Support Education Activity, Text Message-Based Navigation Intervention
Other · Behavioral
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
50 Years to 75 Years
Enrollment
9,745 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 20, 2026, 2:54 AM EDT
Completed Not applicable Interventional

Acupressure for Knee Pain in Older Adults

NCT02003443
View directory record Official record
Conditions
Osteoarthritis
Interventions
Self-Administered Acupressure
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
65 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 14, 2022 · Synced Oct 20, 2026, 2:54 AM EDT
Completed No phase listed Observational

Evaluating the Efficacy of a Digital Platform to Deliver Comprehensive Treatment for Opioid Use Disorder

NCT05529225
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Not listed
Lead sponsor
Boulder Care
Industry
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 20, 2026, 2:54 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sleep as a Mechanism of Change in Alcohol Use

NCT06286774
View directory record Official record
Conditions
Insomnia, Alcohol; Harmful Use
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 49 Years
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 20, 2026, 2:54 AM EDT
Completed Phase 1 Interventional

Task-Based Grounding Program

NCT04648553
View directory record Official record
Conditions
Aggressive, Defiant Disorder, Oppositional, Attention Deficit Hyperactivity Disorder
Interventions
Task-Based Grounding, Connected Care (Enhanced Treatment as usual)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
9 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Oct 20, 2026, 2:54 AM EDT
Completed Not applicable Interventional

Intensive Outpatient Treatment for Suicidal Veterans

NCT01334372
View directory record Official record
Conditions
Suicidality
Interventions
CAMS
Behavioral
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 89 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 13, 2011 · Synced Oct 20, 2026, 2:54 AM EDT
Completed Not applicable Interventional

Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 1

NCT06287801
View directory record Official record
Conditions
Healthy Aging, Health Care Utilization, Health-Related Behavior
Interventions
Annual Wellness Visit, Geriatric Resources and Assessment for the Care of Elders
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
65 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 20, 2026, 2:54 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Stepped Care for Depression and Musculoskeletal Pain

NCT00118430
View directory record Official record
Conditions
Pain, Depression
Interventions
Stepped Care, Antidepressants, Usual Care
Behavioral · Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Oct 20, 2026, 2:54 AM EDT
Recruiting Not applicable Interventional

Readiness Brain Operation Optimization Training (ReBOOT) for Epilepsy Surgery

NCT05992402
View directory record Official record
Conditions
Epilepsy
Interventions
ReBOOT program
Behavioral
Lead sponsor
Kayela Arrotta
Other
Eligibility
18 Years to 60 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 20, 2026, 2:54 AM EDT
Not listed Not applicable Interventional

De-resuscitation Informed by Ultrasound for Patients With Sepsis

NCT04921319
View directory record Official record
Conditions
Sepsis, Septic Shock, Sepsis, Severe, Volume Overload
Interventions
VExUS score
Diagnostic Test
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Oct 20, 2026, 2:54 AM EDT
Completed Phase 3 Interventional Results available

Diuretic Comparison Project

NCT02185417
View directory record Official record
Conditions
Hypertension
Interventions
Hydrochlorothiazide (HCTZ), Chlorthalidone (CTD)
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years and older
Enrollment
20,723 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
69
States / cities
Birmingham, Alabama • Anchorage, Alaska • Fayetteville, Arkansas + 64 more
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Oct 20, 2026, 2:54 AM EDT
Completed Not applicable Interventional

Comprehensive Intervention to Evaluate Outcomes AND Cost in Hospitalized Surgical Patients With Diabetes Mellitus (DM)

NCT02065050
View directory record Official record
Conditions
Diabetes
Interventions
team-based care
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 20, 2026, 2:54 AM EDT
Completed Not applicable Interventional Results available

24-hour Oral Morphine Equivalent Based Opioid Prescribing After Surgery

NCT04043143
View directory record Official record
Conditions
Opioid Use
Interventions
Arm 1 Prescription As Usual, Arm 2 Prescription Tool Intervention
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 27, 2021 · Synced Oct 20, 2026, 2:54 AM EDT
Completed Not applicable Interventional Results available

Behavioral Activation Therapy for Rural Veterans With Diabetes and Depression

NCT01572389
View directory record Official record
Conditions
Diabetes Mellitus, Depression
Interventions
Healthy Outcomes through Patient Empowerment (HOPE), Enhanced Usual Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2017 · Synced Oct 20, 2026, 2:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical and Hospital Stay Effects of Reiki and Manual Therapy After Open Heart Surgery

NCT05853250
View directory record Official record
Conditions
Coronary Artery Diseases, Valvular Heart Diseases
Interventions
Reiki/manual therapy
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
272 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 20, 2026, 2:54 AM EDT